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Compile Data Set for Download or QSAR

Found 3 hits of ic50 for monomerid = 50240808   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fibroblast growth factor receptor 2


(Homo sapiens (Human))
BDBM50240808
PNG
(CHEMBL4078176)
Show SMILES Cc1n[nH]c2ccc(cc12)-c1cc(N[C@@H](CO)c2ccccc2)cnc1-c1ccsc1 |r|
Show InChI InChI=1S/C25H22N4OS/c1-16-21-11-18(7-8-23(21)29-28-16)22-12-20(13-26-25(22)19-9-10-31-15-19)27-24(14-30)17-5-3-2-4-6-17/h2-13,15,24,27,30H,14H2,1H3,(H,28,29)/t24-/m0/s1
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Article
PubMed
n/an/a 57n/an/an/an/an/an/a



University of Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of recombinant human FGFR2 using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISA


J Med Chem 60: 6018-6035 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00076
BindingDB Entry DOI: 10.7270/Q2K939NC
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))
BDBM50240808
PNG
(CHEMBL4078176)
Show SMILES Cc1n[nH]c2ccc(cc12)-c1cc(N[C@@H](CO)c2ccccc2)cnc1-c1ccsc1 |r|
Show InChI InChI=1S/C25H22N4OS/c1-16-21-11-18(7-8-23(21)29-28-16)22-12-20(13-26-25(22)19-9-10-31-15-19)27-24(14-30)17-5-3-2-4-6-17/h2-13,15,24,27,30H,14H2,1H3,(H,28,29)/t24-/m0/s1
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Article
PubMed
n/an/a 327n/an/an/an/an/an/a



University of Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against L-Hexonate Dehydrogenase (L-HDH) from rat kidney (RK)


J Med Chem 60: 6018-6035 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00076
BindingDB Entry DOI: 10.7270/Q2K939NC
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM50240808
PNG
(CHEMBL4078176)
Show SMILES Cc1n[nH]c2ccc(cc12)-c1cc(N[C@@H](CO)c2ccccc2)cnc1-c1ccsc1 |r|
Show InChI InChI=1S/C25H22N4OS/c1-16-21-11-18(7-8-23(21)29-28-16)22-12-20(13-26-25(22)19-9-10-31-15-19)27-24(14-30)17-5-3-2-4-6-17/h2-13,15,24,27,30H,14H2,1H3,(H,28,29)/t24-/m0/s1
PDB
MMDB

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UniProtKB/SwissProt

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antibodypedia
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CHEMBL
PC cid
PC sid
UniChem

Patents


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Article
PubMed
n/an/a 970n/an/an/an/an/an/a



University of Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of recombinant human FGFR3 using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISA


J Med Chem 60: 6018-6035 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00076
BindingDB Entry DOI: 10.7270/Q2K939NC
More data for this
Ligand-Target Pair