Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM50247033 (2-amino-3-(5-(benzyloxy)-1H-indol-3-yl)propanoic a...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.73E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Peking University Curated by ChEMBL | Assay Description Inhibition of aminopeptidase activity of human leukotriene A4 hydrolase assessed as para-nitroanilide release by spectrophotometry | J Med Chem 51: 7882-8 (2008) Article DOI: 10.1021/jm8010096 BindingDB Entry DOI: 10.7270/Q2VH5NQQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM50247033 (2-amino-3-(5-(benzyloxy)-1H-indol-3-yl)propanoic a...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.73E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Peking University Curated by ChEMBL | Assay Description Inhibition of human LTA4H aminopeptidase activity using Ala-p-nitroanilide as substrate incubated for 2 mins prior to substrate addition measured for... | Eur J Med Chem 59: 160-7 (2013) Article DOI: 10.1016/j.ejmech.2012.10.057 BindingDB Entry DOI: 10.7270/Q27P90QH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phospholipase A2, membrane associated (Homo sapiens (Human)) | BDBM50247033 (2-amino-3-(5-(benzyloxy)-1H-indol-3-yl)propanoic a...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.21E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Peking University Curated by ChEMBL | Assay Description Inhibition of human nonpancreatic secretory phospholipase A2 using 1,2-dimyristoyl-sn-glycero-3-phosphocholine as substrate after 10 mins by spectrop... | Eur J Med Chem 59: 160-7 (2013) Article DOI: 10.1016/j.ejmech.2012.10.057 BindingDB Entry DOI: 10.7270/Q27P90QH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phospholipase A2, membrane associated (Homo sapiens (Human)) | BDBM50247033 (2-amino-3-(5-(benzyloxy)-1H-indol-3-yl)propanoic a...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.21E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Peking University Curated by ChEMBL | Assay Description Inhibition of human nonpancreatic secretory phospholipase A2 | J Med Chem 51: 7882-8 (2008) Article DOI: 10.1021/jm8010096 BindingDB Entry DOI: 10.7270/Q2VH5NQQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM50247033 (2-amino-3-(5-(benzyloxy)-1H-indol-3-yl)propanoic a...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.31E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Peking University Curated by ChEMBL | Assay Description Inhibition of epoxide hydrolase activity of human leukotriene A4 hydrolase assessed as LTB4 level by ELISA | J Med Chem 51: 7882-8 (2008) Article DOI: 10.1021/jm8010096 BindingDB Entry DOI: 10.7270/Q2VH5NQQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM50247033 (2-amino-3-(5-(benzyloxy)-1H-indol-3-yl)propanoic a...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.31E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Peking University Curated by ChEMBL | Assay Description Inhibition of human LTA4H epoxide hydrolase activity using LTA4 as substrate incubated for 15 mins prior to substrate addition measured after 10 mins... | Eur J Med Chem 59: 160-7 (2013) Article DOI: 10.1016/j.ejmech.2012.10.057 BindingDB Entry DOI: 10.7270/Q27P90QH | |||||||||||
More data for this Ligand-Target Pair |