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Compile Data Set for Download or QSAR

Found 2 hits of ic50 for monomerid = 50249081   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (Human))
BDBM50249081
PNG
(CHEMBL452136 | N'-(2,4-dihydroxy-6-methylbenzylide...)
Show SMILES Cc1cccc(OCC(=O)NN=Cc2c(C)cc(O)cc2O)c1 |w:11.10|
Show InChI InChI=1S/C17H18N2O4/c1-11-4-3-5-14(6-11)23-10-17(22)19-18-9-15-12(2)7-13(20)8-16(15)21/h3-9,20-21H,10H2,1-2H3,(H,19,22)
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.09E+3n/an/an/an/an/an/a



Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximity assay in...


Eur J Med Chem 44: 1167-71 (2009)


Article DOI: 10.1016/j.ejmech.2008.06.005
BindingDB Entry DOI: 10.7270/Q2251J0Z
More data for this
Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1


(Mus musculus (mouse))
BDBM50249081
PNG
(CHEMBL452136 | N'-(2,4-dihydroxy-6-methylbenzylide...)
Show SMILES Cc1cccc(OCC(=O)NN=Cc2c(C)cc(O)cc2O)c1 |w:11.10|
Show InChI InChI=1S/C17H18N2O4/c1-11-4-3-5-14(6-11)23-10-17(22)19-18-9-15-12(2)7-13(20)8-16(15)21/h3-9,20-21H,10H2,1-2H3,(H,19,22)
PDB
MMDB

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UniProtKB/SwissProt

B.MOAD
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GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of mouse 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximity assay in...


Eur J Med Chem 44: 1167-71 (2009)


Article DOI: 10.1016/j.ejmech.2008.06.005
BindingDB Entry DOI: 10.7270/Q2251J0Z
More data for this
Ligand-Target Pair