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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50251033   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM50251033
PNG
(CHEMBL4066604)
Show SMILES CC1CCc2c(C1)sc1nc([nH]c(=O)c21)-c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C18H15F3N2OS/c1-9-2-7-12-13(8-9)25-17-14(12)16(24)22-15(23-17)10-3-5-11(6-4-10)18(19,20)21/h3-6,9H,2,7-8H2,1H3,(H,22,23,24)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of His/thioredoxin-tagged human recombinant BRD4 bromodomain-1 (43 to 166 residues) expressed in Escherichia coli BL21 Star (DE3) pre-incu...

J Med Chem 60: 9990-10012 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00275
BindingDB Entry DOI: 10.7270/Q2M32Z68
More data for this
Ligand-Target Pair