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Compile Data Set for Download or QSAR

Found 2 hits of ic50 for monomerid = 50265500   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Secreted frizzled-related protein 1


(Homo sapiens (Human))
BDBM50265500
PNG
((S)-tert-butyl 2-(4-(5-(phenylsulfonyl)-2-(trifluo...)
Show SMILES CC(C)(C)OC(=O)N1CCC[C@H]1C(=O)N1CCC(CC1)NS(=O)(=O)c1cc(ccc1C(F)(F)F)S(=O)(=O)c1ccccc1 |r|
Show InChI InChI=1S/C28H34F3N3O7S2/c1-27(2,3)41-26(36)34-15-7-10-23(34)25(35)33-16-13-19(14-17-33)32-43(39,40)24-18-21(11-12-22(24)28(29,30)31)42(37,38)20-8-5-4-6-9-20/h4-6,8-9,11-12,18-19,23,32H,7,10,13-17H2,1-3H3/t23-/m0/s1
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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 60n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assay


Bioorg Med Chem 18: 190-201 (2010)


Article DOI: 10.1016/j.bmc.2009.11.002
BindingDB Entry DOI: 10.7270/Q2PZ58Z7
More data for this
Ligand-Target Pair
Secreted frizzled-related protein 1


(Homo sapiens (Human))
BDBM50265500
PNG
((S)-tert-butyl 2-(4-(5-(phenylsulfonyl)-2-(trifluo...)
Show SMILES CC(C)(C)OC(=O)N1CCC[C@H]1C(=O)N1CCC(CC1)NS(=O)(=O)c1cc(ccc1C(F)(F)F)S(=O)(=O)c1ccccc1 |r|
Show InChI InChI=1S/C28H34F3N3O7S2/c1-27(2,3)41-26(36)34-15-7-10-23(34)25(35)33-16-13-19(14-17-33)32-43(39,40)24-18-21(11-12-22(24)28(29,30)31)42(37,38)20-8-5-4-6-9-20/h4-6,8-9,11-12,18-19,23,32H,7,10,13-17H2,1-3H3/t23-/m0/s1
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 60n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Binding affinity to human purified SARP2 by fluorescent polarization assay


J Med Chem 52: 105-16 (2009)


Article DOI: 10.1021/jm801144h
BindingDB Entry DOI: 10.7270/Q2NZ87HT
More data for this
Ligand-Target Pair