Found 5 hits of ic50 for monomerid = 50281371 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Cytochrome P450 2D6
(Homo sapiens (Human)) | BDBM50281371
![PNG](/data/jpeg/tenK5028/BindingDB_50281371.png) (CHEMBL4171368)Show InChI InChI=1S/C15H22N4O2/c1-3-4-10(7-8-20)17-14-12-6-5-11(21-2)9-13(12)18-15(16)19-14/h5-6,9-10,20H,3-4,7-8H2,1-2H3,(H3,16,17,18,19)/t10-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Infectious Diseases-Diagnostics BVBA
Curated by ChEMBL
| Assay Description Inhibition of CYP2D6 (unknown origin) |
J Med Chem 61: 6236-6246 (2018)
Article DOI: 10.1021/acs.jmedchem.8b00643 BindingDB Entry DOI: 10.7270/Q2057JFF |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50281371
![PNG](/data/jpeg/tenK5028/BindingDB_50281371.png) (CHEMBL4171368)Show InChI InChI=1S/C15H22N4O2/c1-3-4-10(7-8-20)17-14-12-6-5-11(21-2)9-13(12)18-15(16)19-14/h5-6,9-10,20H,3-4,7-8H2,1-2H3,(H3,16,17,18,19)/t10-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.78E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Infectious Diseases-Diagnostics BVBA
Curated by ChEMBL
| Assay Description Inhibition of 5-HT2A receptor (unknown origin) |
J Med Chem 61: 6236-6246 (2018)
Article DOI: 10.1021/acs.jmedchem.8b00643 BindingDB Entry DOI: 10.7270/Q2057JFF |
More data for this Ligand-Target Pair | |
Adenosine receptor A1
(Homo sapiens (Human)) | BDBM50281371
![PNG](/data/jpeg/tenK5028/BindingDB_50281371.png) (CHEMBL4171368)Show InChI InChI=1S/C15H22N4O2/c1-3-4-10(7-8-20)17-14-12-6-5-11(21-2)9-13(12)18-15(16)19-14/h5-6,9-10,20H,3-4,7-8H2,1-2H3,(H3,16,17,18,19)/t10-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.34E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Infectious Diseases-Diagnostics BVBA
Curated by ChEMBL
| Assay Description Inhibition of adenosine A1 receptor (unknown origin) |
J Med Chem 61: 6236-6246 (2018)
Article DOI: 10.1021/acs.jmedchem.8b00643 BindingDB Entry DOI: 10.7270/Q2057JFF |
More data for this Ligand-Target Pair | |
D(1A) dopamine receptor
(Homo sapiens (Human)) | BDBM50281371
![PNG](/data/jpeg/tenK5028/BindingDB_50281371.png) (CHEMBL4171368)Show InChI InChI=1S/C15H22N4O2/c1-3-4-10(7-8-20)17-14-12-6-5-11(21-2)9-13(12)18-15(16)19-14/h5-6,9-10,20H,3-4,7-8H2,1-2H3,(H3,16,17,18,19)/t10-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.75E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Infectious Diseases-Diagnostics BVBA
Curated by ChEMBL
| Assay Description Inhibition of dopamine D1 receptor (unknown origin) |
J Med Chem 61: 6236-6246 (2018)
Article DOI: 10.1021/acs.jmedchem.8b00643 BindingDB Entry DOI: 10.7270/Q2057JFF |
More data for this Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50281371
![PNG](/data/jpeg/tenK5028/BindingDB_50281371.png) (CHEMBL4171368)Show InChI InChI=1S/C15H22N4O2/c1-3-4-10(7-8-20)17-14-12-6-5-11(21-2)9-13(12)18-15(16)19-14/h5-6,9-10,20H,3-4,7-8H2,1-2H3,(H3,16,17,18,19)/t10-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Infectious Diseases-Diagnostics BVBA
Curated by ChEMBL
| Assay Description Inhibition of radioligand binding to human ERG expressed in HEK293 cell membranes by scintillation counting method |
J Med Chem 61: 6236-6246 (2018)
Article DOI: 10.1021/acs.jmedchem.8b00643 BindingDB Entry DOI: 10.7270/Q2057JFF |
More data for this Ligand-Target Pair | |