Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human)) | BDBM50306211 (CHEMBL611317 | {[17-(diphosphonomethyl)-26,28-dihy...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Academy of Sciences of Ukraine Curated by ChEMBL | Assay Description Inhibition of recombinant full length PTP1B (unknown origin) assessed as p-nitrophenyl phosphate conversion to p-nitrophenol after 10 mins by spectro... | Bioorg Med Chem Lett 23: 5619-23 (2013) Article DOI: 10.1016/j.bmcl.2013.08.040 BindingDB Entry DOI: 10.7270/Q29Z96BF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human)) | BDBM50306211 (CHEMBL611317 | {[17-(diphosphonomethyl)-26,28-dihy...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Academy of Sciences of Ukraine Curated by ChEMBL | Assay Description Inhibition of SHP2 (unknown origin) assessed as p-nitrophenyl phosphate conversion to p-nitrophenol after 10 mins by spectrophotometric analysis | Bioorg Med Chem Lett 23: 5619-23 (2013) Article DOI: 10.1016/j.bmcl.2013.08.040 BindingDB Entry DOI: 10.7270/Q29Z96BF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human)) | BDBM50306211 (CHEMBL611317 | {[17-(diphosphonomethyl)-26,28-dihy...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Academy of Sciences of Ukraine Curated by ChEMBL | Assay Description Inhibition of recombinant truncated PTP1B (unknown origin) using pTyr1146 as substrate assessed as inorganic phosphate level after 20 mins by spectro... | Bioorg Med Chem Lett 23: 5619-23 (2013) Article DOI: 10.1016/j.bmcl.2013.08.040 BindingDB Entry DOI: 10.7270/Q29Z96BF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human)) | BDBM50306211 (CHEMBL611317 | {[17-(diphosphonomethyl)-26,28-dihy...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Academy of Sciences of Ukraine Curated by ChEMBL | Assay Description Inhibition of TCPTP (unknown origin) assessed as p-nitrophenyl phosphate conversion to p-nitrophenol after 10 mins by spectrophotometric analysis | Bioorg Med Chem Lett 23: 5619-23 (2013) Article DOI: 10.1016/j.bmcl.2013.08.040 BindingDB Entry DOI: 10.7270/Q29Z96BF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein phosphatase C (Homo sapiens (Human)) | BDBM50306211 (CHEMBL611317 | {[17-(diphosphonomethyl)-26,28-dihy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
National Academy of Sciences of Ukraine Curated by ChEMBL | Assay Description Inhibition of CD45 (unknown origin) assessed as p-nitrophenyl phosphate conversion to p-nitrophenol after 10 mins by spectrophotometric analysis | Bioorg Med Chem Lett 23: 5619-23 (2013) Article DOI: 10.1016/j.bmcl.2013.08.040 BindingDB Entry DOI: 10.7270/Q29Z96BF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein phosphatase beta (Homo sapiens (Human)) | BDBM50306211 (CHEMBL611317 | {[17-(diphosphonomethyl)-26,28-dihy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
National Academy of Sciences of Ukraine Curated by ChEMBL | Assay Description Inhibition of human recombinant PTPbeta | Bioorg Med Chem Lett 20: 483-7 (2010) Article DOI: 10.1016/j.bmcl.2009.11.126 BindingDB Entry DOI: 10.7270/Q2RB74QM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein phosphatase beta (Homo sapiens (Human)) | BDBM50306211 (CHEMBL611317 | {[17-(diphosphonomethyl)-26,28-dihy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
National Academy of Sciences of Ukraine Curated by ChEMBL | Assay Description Inhibition of PTPbeta (unknown origin) assessed as p-nitrophenyl phosphate conversion to p-nitrophenol after 10 mins by spectrophotometric analysis | Bioorg Med Chem Lett 23: 5619-23 (2013) Article DOI: 10.1016/j.bmcl.2013.08.040 BindingDB Entry DOI: 10.7270/Q29Z96BF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein phosphatase F (Homo sapiens (Human)) | BDBM50306211 (CHEMBL611317 | {[17-(diphosphonomethyl)-26,28-dihy...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
National Academy of Sciences of Ukraine Curated by ChEMBL | Assay Description Inhibition of LAR (unknown origin) assessed as p-nitrophenyl phosphate conversion to p-nitrophenol after 10 mins by spectrophotometric analysis | Bioorg Med Chem Lett 23: 5619-23 (2013) Article DOI: 10.1016/j.bmcl.2013.08.040 BindingDB Entry DOI: 10.7270/Q29Z96BF | |||||||||||
More data for this Ligand-Target Pair |