BindingDB PrimarySearch

Found 10 hits of ic50 for monomerid = 50330794
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50330794 (2-Hydroxy-4-isopropyl-cyclohepta-2,4,6-trienone \| ...) Show SMILES CC(C)c1cccc(=O)c(O)c1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Theoretical Medicine, Inc. Curated by ChEMBL					Assay Description Non-competitive inhibition of mushroom tyrosinase				Bioorg Med Chem 22: 6193-200 (2014) Article DOI: 10.1016/j.bmc.2014.08.027 BindingDB Entry DOI: 10.7270/Q2DV1MG2
Institute for Theoretical Medicine, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50330794 (2-Hydroxy-4-isopropyl-cyclohepta-2,4,6-trienone \| ...) Show SMILES CC(C)c1cccc(=O)c(O)c1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Theoretical Medicine, Inc. Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase after 15 mins				Bioorg Med Chem 18: 8112-8 (2010) Article DOI: 10.1016/j.bmc.2010.08.056 BindingDB Entry DOI: 10.7270/Q2JH3MF5
Institute for Theoretical Medicine, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50330794 (2-Hydroxy-4-isopropyl-cyclohepta-2,4,6-trienone \| ...) Show SMILES CC(C)c1cccc(=O)c(O)c1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase				J Med Chem 61: 7395-7418 (2018) Article DOI: 10.1021/acs.jmedchem.7b00967 BindingDB Entry DOI: 10.7270/Q2CN77C2
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50330794 (2-Hydroxy-4-isopropyl-cyclohepta-2,4,6-trienone \| ...) Show SMILES CC(C)c1cccc(=O)c(O)c1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase				J Med Chem 61: 7395-7418 (2018) Article DOI: 10.1021/acs.jmedchem.7b00967 BindingDB Entry DOI: 10.7270/Q2CN77C2
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Carboxypeptidase A1 (Bos taurus (bovine))	BDBM50330794 (2-Hydroxy-4-isopropyl-cyclohepta-2,4,6-trienone \| ...) Show SMILES CC(C)c1cccc(=O)c(O)c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.76E+3	n/a	n/a	n/a	n/a	n/a	n/a
Osaka Organic Chemical Industry, Ltd Curated by ChEMBL					Assay Description Inhibition of Bos taurus (bovine) pancrease carboxypeptidase A after 15 min				Biol Pharm Bull 26: 1487-90 (2003) Article DOI: 10.1248/bpb.26.1487 BindingDB Entry DOI: 10.7270/Q2G163RP
Osaka Organic Chemical Industry, Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosinase (Homo sapiens (Human))	BDBM50330794 (2-Hydroxy-4-isopropyl-cyclohepta-2,4,6-trienone \| ...) Show SMILES CC(C)c1cccc(=O)c(O)c1 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.98E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Theoretical Medicine, Inc. Curated by ChEMBL					Assay Description Competitive inhibition of tyrosinase in human G-361 cells incubated for 10 mins measured for 2 hrs by MBTH-based spectrophotometry				Bioorg Med Chem 22: 6193-200 (2014) Article DOI: 10.1016/j.bmc.2014.08.027 BindingDB Entry DOI: 10.7270/Q2DV1MG2
Institute for Theoretical Medicine, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosinase (Homo sapiens (Human))	BDBM50330794 (2-Hydroxy-4-isopropyl-cyclohepta-2,4,6-trienone \| ...) Show SMILES CC(C)c1cccc(=O)c(O)c1 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.98E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human tyrosinase				J Med Chem 61: 7395-7418 (2018) Article DOI: 10.1021/acs.jmedchem.7b00967 BindingDB Entry DOI: 10.7270/Q2CN77C2
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosinase (Homo sapiens (Human))	BDBM50330794 (2-Hydroxy-4-isopropyl-cyclohepta-2,4,6-trienone \| ...) Show SMILES CC(C)c1cccc(=O)c(O)c1 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.98E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human tyrosinase				J Med Chem 61: 7395-7418 (2018) Article DOI: 10.1021/acs.jmedchem.7b00967 BindingDB Entry DOI: 10.7270/Q2CN77C2
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Collagenase ColG (Clostridium histolyticum)	BDBM50330794 (2-Hydroxy-4-isopropyl-cyclohepta-2,4,6-trienone \| ...) Show SMILES CC(C)c1cccc(=O)c(O)c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Osaka Organic Chemical Industry, Ltd Curated by ChEMBL					Assay Description Inhibition of Clostridium histolyticum collagenase after 15 min				Biol Pharm Bull 26: 1487-90 (2003) Article DOI: 10.1248/bpb.26.1487 BindingDB Entry DOI: 10.7270/Q2G163RP
Osaka Organic Chemical Industry, Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
Thermolysin (Bacillus thermoproteolyticus)	BDBM50330794 (2-Hydroxy-4-isopropyl-cyclohepta-2,4,6-trienone \| ...) Show SMILES CC(C)c1cccc(=O)c(O)c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Osaka Organic Chemical Industry, Ltd Curated by ChEMBL					Assay Description Inhibition of Bacillus thermoproteolyticus thermolysin after 15 min				Biol Pharm Bull 26: 1487-90 (2003) Article DOI: 10.1248/bpb.26.1487 BindingDB Entry DOI: 10.7270/Q2G163RP
Osaka Organic Chemical Industry, Ltd Curated by ChEMBL					More data for this Ligand-Target Pair