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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50338251   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Inhibitor of nuclear factor kappa-B kinase subunit beta


(Homo sapiens (Human))		BDBM50338251
PNG
(7-(pyridin-4-ylmethyl)-2-ureido-5,7-dihydro-4H-thi...)
Show SMILES NC(=O)Nc1sc-2c(CCc3nn(Cc4ccncc4)cc-23)c1C(N)=O
Show InChI InChI=1S/C17H16N6O2S/c18-15(24)13-10-1-2-12-11(14(10)26-16(13)21-17(19)25)8-23(22-12)7-9-3-5-20-6-4-9/h3-6,8H,1-2,7H2,(H2,18,24)(H3,19,21,25)
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Article
PubMed
n/an/a 2.30E+3n/an/an/an/an/an/a



Kyorin Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human IKK-beta by substrate phosphorylation assay

Bioorg Med Chem Lett 21: 1758-62 (2011)


Article DOI: 10.1016/j.bmcl.2011.01.069
BindingDB Entry DOI: 10.7270/Q2TX3FPV
More data for this
Ligand-Target Pair