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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50399900   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cGMP-specific 3',5'-cyclic phosphodiesterase


(Homo sapiens (Human))		BDBM50399900
PNG
(CHEMBL2180662)
Show SMILES CCCOc1ccc(cc1-c1nc(cc(=O)[nH]1)C(F)(F)F)S(=O)(=O)N1CCN(C)CC1
Show InChI InChI=1S/C19H23F3N4O4S/c1-3-10-30-15-5-4-13(31(28,29)26-8-6-25(2)7-9-26)11-14(15)18-23-16(19(20,21)22)12-17(27)24-18/h4-5,11-12H,3,6-10H2,1-2H3,(H,23,24,27)
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Article
PubMed
n/an/a 312n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDE5A by [3H]cGMP based tritium scintillation proximity assay

J Med Chem 55: 10540-50 (2012)


Article DOI: 10.1021/jm301159y
BindingDB Entry DOI: 10.7270/Q2154J6G
More data for this
Ligand-Target Pair