Compile Data Set for Download or QSAR

Found 4 hits of ic50 for monomerid = 50411954   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATP-dependent translocase ABCB1 (Homo sapiens (Human))	BDBM50411954 (CHEMBL259789) Show SMILES COc1cc2CCN(CCc3ccc(NC(=O)c4cccc(Br)c4)cc3)Cc2cc1OC Show InChI InChI=1S/C26H27BrN2O3/c1-31-24-15-19-11-13-29(17-21(19)16-25(24)32-2)12-10-18-6-8-23(9-7-18)28-26(30)20-4-3-5-22(27)14-20/h3-9,14-16H,10-13,17H2,1-2H3,(H,28,30)	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of P-glycoprotein-mediated multidrug resistance in adriamycin-resistant human A2780/ADR cells by calcein AM assay				Bioorg Med Chem 17: 2524-35 (2009) Article DOI: 10.1016/j.bmc.2009.01.072 BindingDB Entry DOI: 10.7270/Q2X63QS6
					More data for this Ligand-Target Pair
ATP-dependent translocase ABCB1 (Homo sapiens (Human))	BDBM50411954 (CHEMBL259789) Show SMILES COc1cc2CCN(CCc3ccc(NC(=O)c4cccc(Br)c4)cc3)Cc2cc1OC Show InChI InChI=1S/C26H27BrN2O3/c1-31-24-15-19-11-13-29(17-21(19)16-25(24)32-2)12-10-18-6-8-23(9-7-18)28-26(30)20-4-3-5-22(27)14-20/h3-9,14-16H,10-13,17H2,1-2H3,(H,28,30)	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.29E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human Pgp in A2780 cells after 30 mins by calcein AM assay				Bioorg Med Chem 16: 2448-62 (2008) Article DOI: 10.1016/j.bmc.2007.11.057 BindingDB Entry DOI: 10.7270/Q2QN67PT
					More data for this Ligand-Target Pair
ATP-dependent translocase ABCB1 (Homo sapiens (Human))	BDBM50411954 (CHEMBL259789) Show SMILES COc1cc2CCN(CCc3ccc(NC(=O)c4cccc(Br)c4)cc3)Cc2cc1OC Show InChI InChI=1S/C26H27BrN2O3/c1-31-24-15-19-11-13-29(17-21(19)16-25(24)32-2)12-10-18-6-8-23(9-7-18)28-26(30)20-4-3-5-22(27)14-20/h3-9,14-16H,10-13,17H2,1-2H3,(H,28,30)	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.24E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human Pgp in A2780 cells after 30 mins by Hoechst 33342 assay				Bioorg Med Chem 16: 2448-62 (2008) Article DOI: 10.1016/j.bmc.2007.11.057 BindingDB Entry DOI: 10.7270/Q2QN67PT
					More data for this Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2 (Homo sapiens (Human))	BDBM50411954 (CHEMBL259789) Show SMILES COc1cc2CCN(CCc3ccc(NC(=O)c4cccc(Br)c4)cc3)Cc2cc1OC Show InChI InChI=1S/C26H27BrN2O3/c1-31-24-15-19-11-13-29(17-21(19)16-25(24)32-2)12-10-18-6-8-23(9-7-18)28-26(30)20-4-3-5-22(27)14-20/h3-9,14-16H,10-13,17H2,1-2H3,(H,28,30)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.29E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of ABCG2 in human mitoxantrone-resistant MCF7 cells by Hoechst 33342 assay				Bioorg Med Chem 16: 8224-36 (2008) Article DOI: 10.1016/j.bmc.2008.07.034 BindingDB Entry DOI: 10.7270/Q2765GK5
					More data for this Ligand-Target Pair