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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50419218   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium- and chloride-dependent glycine transporter 1


(Homo sapiens (Human))		BDBM50419218
PNG
(CHEMBL1834683)
Show SMILES CCC(C)N(CC(=O)Nc1cc(F)cc(F)c1)C(=O)c1ccc(cc1)-c1ccccn1
Show InChI InChI=1S/C24H23F2N3O2/c1-3-16(2)29(15-23(30)28-21-13-19(25)12-20(26)14-21)24(31)18-9-7-17(8-10-18)22-6-4-5-11-27-22/h4-14,16H,3,15H2,1-2H3,(H,28,30)
PDB

KEGG

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 398n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibition of GlyT1 expressed in HEK293 cells assessed as inhibition of [3H]glycine uptake by scintillation proximity binding assay

Bioorg Med Chem Lett 21: 6176-9 (2011)


Article DOI: 10.1016/j.bmcl.2011.07.096
BindingDB Entry DOI: 10.7270/Q2251KF6
More data for this
Ligand-Target Pair