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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50420724   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform


(Homo sapiens (Human))		BDBM50420724
PNG
(CHEMBL2087485)
Show SMILES CS(=O)(=O)N1C2CCC1CN(Cc1cn3cc(nc(N4CCOCC4)c3n1)-c1cnc(N)nc1)C2
Show InChI InChI=1S/C22H29N9O3S/c1-35(32,33)31-17-2-3-18(31)13-28(12-17)10-16-11-30-14-19(15-8-24-22(23)25-9-15)27-21(20(30)26-16)29-4-6-34-7-5-29/h8-9,11,14,17-18H,2-7,10,12-13H2,1H3,(H2,23,24,25)
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PC sid
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Similars
Article
PubMed
n/an/a 108n/an/an/an/an/an/a



Spanish National Cancer Research Centre (CNIO)

Curated by ChEMBL


Assay Description
Inhibition of human PI3Kalpha (p110alpha/p85alpha) by ADP accumulation based HTRF assay

Bioorg Med Chem Lett 22: 3460-6 (2012)


Article DOI: 10.1016/j.bmcl.2012.03.090
BindingDB Entry DOI: 10.7270/Q26W9CCB
More data for this
Ligand-Target Pair