Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Ephrin type-B receptor 4 (Homo sapiens (Human)) | BDBM50428742 (CHEMBL2333595) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 68 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Zurich Curated by ChEMBL | Assay Description Inhibition of human myc-tagged full length EphB4 expressed in MEF cells assessed as inhibition of ephrinB2-Fc-induced autophosphorylation incubated f... | J Med Chem 56: 84-96 (2013) Article DOI: 10.1021/jm301187e BindingDB Entry DOI: 10.7270/Q2WW7K1S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ephrin type-B receptor 4 (Homo sapiens (Human)) | BDBM50428742 (CHEMBL2333595) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 91 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Zurich Curated by ChEMBL | Assay Description Inhibition of EphB4 (unknown origin) transfected in CHO cells using Z'-LYTE TYR-1 peptide as substrate after 2 hrs by FRET assay | J Med Chem 56: 84-96 (2013) Article DOI: 10.1021/jm301187e BindingDB Entry DOI: 10.7270/Q2WW7K1S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM50428742 (CHEMBL2333595) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Zurich Curated by ChEMBL | Assay Description Inhibition of Src (unknown origin) using [gamma-33P]ATP after 30 mins by radiometric assay | J Med Chem 56: 84-96 (2013) Article DOI: 10.1021/jm301187e BindingDB Entry DOI: 10.7270/Q2WW7K1S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ephrin type-B receptor 4 (Homo sapiens (Human)) | BDBM50428742 (CHEMBL2333595) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 139 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Zurich Curated by ChEMBL | Assay Description Inhibition of EphB4 (unknown origin) transfected in CHO cells using [gamma-33P]ATP by radiometric assay | J Med Chem 56: 84-96 (2013) Article DOI: 10.1021/jm301187e BindingDB Entry DOI: 10.7270/Q2WW7K1S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Yes (Homo sapiens (Human)) | BDBM50428742 (CHEMBL2333595) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 496 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Zurich Curated by ChEMBL | Assay Description Inhibition of Yes1 (unknown origin) using [gamma-33P]ATP after 30 mins by radiometric assay | J Med Chem 56: 84-96 (2013) Article DOI: 10.1021/jm301187e BindingDB Entry DOI: 10.7270/Q2WW7K1S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM50428742 (CHEMBL2333595) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 617 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Zurich Curated by ChEMBL | Assay Description Inhibition of Lck (unknown origin) using [gamma-33P]ATP after 30 mins by radiometric assay | J Med Chem 56: 84-96 (2013) Article DOI: 10.1021/jm301187e BindingDB Entry DOI: 10.7270/Q2WW7K1S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 (Homo sapiens (Human)) | BDBM50428742 (CHEMBL2333595) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.28E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Zurich Curated by ChEMBL | Assay Description Inhibition of Abl (unknown origin) using [gamma-33P]ATP after 30 mins by radiometric assay | J Med Chem 56: 84-96 (2013) Article DOI: 10.1021/jm301187e BindingDB Entry DOI: 10.7270/Q2WW7K1S | |||||||||||
More data for this Ligand-Target Pair |