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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50436230   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transforming protein RhoA


(Homo sapiens (Human))		BDBM50436230
PNG
(CHEMBL2398684)
Show SMILES Cc1cccc(c1)C(=O)N1CCCC(C1)C(=O)Nc1ccc(Cl)cc1
Show InChI InChI=1S/C20H21ClN2O2/c1-14-4-2-5-15(12-14)20(25)23-11-3-6-16(13-23)19(24)22-18-9-7-17(21)8-10-18/h2,4-5,7-10,12,16H,3,6,11,13H2,1H3,(H,22,24)
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Article
PubMed
n/an/a 3.50E+4n/an/an/an/an/an/a



College of Pharmacy

Curated by ChEMBL


Assay Description
Inhibition of RhoC-mediated pathway in human PC3 cells assessed as inhibition of SRE-regulated gene transcription by luciferase reporter gene assay

Bioorg Med Chem Lett 23: 3826-32 (2013)


Article DOI: 10.1016/j.bmcl.2013.04.080
BindingDB Entry DOI: 10.7270/Q28P61XS
More data for this
Ligand-Target Pair