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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50438886   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
DNA-(apurinic or apyrimidinic site) endonuclease


(Homo sapiens (Human))		BDBM50438886
PNG
(CHEMBL2420489)
Show SMILES COc1ccc(cc1OC)-c1csc(c1)C(=O)N1CCCC(C1)C(=O)P(=O)(OC)OC
Show InChI InChI=1S/C21H26NO7PS/c1-26-17-8-7-14(10-18(17)27-2)16-11-19(31-13-16)20(23)22-9-5-6-15(12-22)21(24)30(25,28-3)29-4/h7-8,10-11,13,15H,5-6,9,12H2,1-4H3
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MMDB

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PC cid
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UniChem
Article
PubMed
n/an/a>2.00E+5n/an/an/an/an/an/a



University of Manchester

Curated by ChEMBL


Assay Description
Inhibition of APE-1 (unknown origin) using double-stranded AP-site containing DNA as substrate after 30 mins by fluorescence assay

J Med Chem 56: 6352-70 (2013)


Article DOI: 10.1021/jm400568p
BindingDB Entry DOI: 10.7270/Q2N017ZB
More data for this
Ligand-Target Pair