Found 3 hits of ic50 for monomerid = 50452485 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50452485
![PNG](/data/jpeg/tenK5045/BindingDB_50452485.png) (CHEMBL2369462)Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@H](CSSC1(C)C)NC(=O)[C@H]1Cc2ccccc2CN1)C(N)=O Show InChI InChI=1S/C48H62N10O9S2/c1-26(59)39(41(50)61)57-47(67)40-48(2,3)69-68-25-38(56-43(63)35-21-28-10-4-5-11-29(28)23-52-35)46(66)54-36(20-27-15-17-31(60)18-16-27)44(64)55-37(22-30-24-51-33-13-7-6-12-32(30)33)45(65)53-34(42(62)58-40)14-8-9-19-49/h4-7,10-13,15-18,24,26,34-40,51-52,59-60H,8-9,14,19-23,25,49H2,1-3H3,(H2,50,61)(H,53,65)(H,54,66)(H,55,64)(H,56,63)(H,57,67)(H,58,62)/t26-,34+,35-,36-,37+,38+,39+,40-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 9.41E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description Binding affinity in competition with [3H]- CTOP in Opioid receptor mu 1 binding to rat brain membrane |
J Med Chem 31: 2170-7 (1988)
BindingDB Entry DOI: 10.7270/Q2J38RJX |
More data for this Ligand-Target Pair | |
Delta-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50452485
![PNG](/data/jpeg/tenK5045/BindingDB_50452485.png) (CHEMBL2369462)Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@H](CSSC1(C)C)NC(=O)[C@H]1Cc2ccccc2CN1)C(N)=O Show InChI InChI=1S/C48H62N10O9S2/c1-26(59)39(41(50)61)57-47(67)40-48(2,3)69-68-25-38(56-43(63)35-21-28-10-4-5-11-29(28)23-52-35)46(66)54-36(20-27-15-17-31(60)18-16-27)44(64)55-37(22-30-24-51-33-13-7-6-12-32(30)33)45(65)53-34(42(62)58-40)14-8-9-19-49/h4-7,10-13,15-18,24,26,34-40,51-52,59-60H,8-9,14,19-23,25,49H2,1-3H3,(H2,50,61)(H,53,65)(H,54,66)(H,55,64)(H,56,63)(H,57,67)(H,58,62)/t26-,34+,35-,36-,37+,38+,39+,40-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description Binding affinity in competition with [3H]- DPDPE in Opioid receptor delta 1 binding to rat brain membrane |
J Med Chem 31: 2170-7 (1988)
BindingDB Entry DOI: 10.7270/Q2J38RJX |
More data for this Ligand-Target Pair | |
Somatostatin receptor type 1/2/3/4/5
(RAT) | BDBM50452485
![PNG](/data/jpeg/tenK5045/BindingDB_50452485.png) (CHEMBL2369462)Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@H](CSSC1(C)C)NC(=O)[C@H]1Cc2ccccc2CN1)C(N)=O Show InChI InChI=1S/C48H62N10O9S2/c1-26(59)39(41(50)61)57-47(67)40-48(2,3)69-68-25-38(56-43(63)35-21-28-10-4-5-11-29(28)23-52-35)46(66)54-36(20-27-15-17-31(60)18-16-27)44(64)55-37(22-30-24-51-33-13-7-6-12-32(30)33)45(65)53-34(42(62)58-40)14-8-9-19-49/h4-7,10-13,15-18,24,26,34-40,51-52,59-60H,8-9,14,19-23,25,49H2,1-3H3,(H2,50,61)(H,53,65)(H,54,66)(H,55,64)(H,56,63)(H,57,67)(H,58,62)/t26-,34+,35-,36-,37+,38+,39+,40-/m1/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 1.36E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description Binding affinity in competition with [125I]- CGP-23996 in somatostatin receptor binding to rat brain membrane |
J Med Chem 31: 2170-7 (1988)
BindingDB Entry DOI: 10.7270/Q2J38RJX |
More data for this Ligand-Target Pair | |