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Compile Data Set for Download or QSAR

Found 3 hits of ic50 for monomerid = 50453606   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM50453606
PNG
(CHEMBL168533)
Show SMILES Oc1ccc(O)c(CNc2ccc(O)c(c2)C(=O)OCCCc2ccccc2)c1
Show InChI InChI=1S/C23H23NO5/c25-19-9-11-21(26)17(13-19)15-24-18-8-10-22(27)20(14-18)23(28)29-12-4-7-16-5-2-1-3-6-16/h1-3,5-6,8-11,13-14,24-27H,4,7,12,15H2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
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CHEMBL
PC cid
PC sid
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PubMed
n/an/a 30n/an/an/an/an/an/a



U266 INSERM-URA D1500 CNRS

Curated by ChEMBL


Assay Description
Inhibitory potency against protein tyrosine kinase activity associated with EGFR was evaluated using ER 22 cell membrane


J Med Chem 37: 845-59 (1994)


BindingDB Entry DOI: 10.7270/Q2QV3KJ3
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM50453606
PNG
(CHEMBL168533)
Show SMILES Oc1ccc(O)c(CNc2ccc(O)c(c2)C(=O)OCCCc2ccccc2)c1
Show InChI InChI=1S/C23H23NO5/c25-19-9-11-21(26)17(13-19)15-24-18-8-10-22(27)20(14-18)23(28)29-12-4-7-16-5-2-1-3-6-16/h1-3,5-6,8-11,13-14,24-27H,4,7,12,15H2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 700n/an/an/an/an/an/a



U266 INSERM-URA D1500 CNRS

Curated by ChEMBL


Assay Description
Inhibition of EGFR(epidermal growth factor receptor) autophosphorylation in ER22 cell membranes


J Med Chem 37: 845-59 (1994)


BindingDB Entry DOI: 10.7270/Q2QV3KJ3
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM50453606
PNG
(CHEMBL168533)
Show SMILES Oc1ccc(O)c(CNc2ccc(O)c(c2)C(=O)OCCCc2ccccc2)c1
Show InChI InChI=1S/C23H23NO5/c25-19-9-11-21(26)17(13-19)15-24-18-8-10-22(27)20(14-18)23(28)29-12-4-7-16-5-2-1-3-6-16/h1-3,5-6,8-11,13-14,24-27H,4,7,12,15H2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 1.50E+3n/an/an/an/an/an/a



U266 INSERM-URA D1500 CNRS

Curated by ChEMBL


Assay Description
Inhibition of EGF-stimulated DNA synthesis in ER22 cells, by measuring [3H]Me-dT incorporation into ER 22 cells


J Med Chem 37: 845-59 (1994)


BindingDB Entry DOI: 10.7270/Q2QV3KJ3
More data for this
Ligand-Target Pair