Found 10 hits of ic50 for monomerid = 50466485 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Solute carrier organic anion transporter family member 1B3
(Homo sapiens (Human)) | BDBM50466485
(CHEMBL4288001)Show SMILES CC#C[C@@H](CC(O)=O)c1ccc(OC[C@H]2COc3ccc(Cl)cc3O2)cc1 |r| Show InChI InChI=1S/C21H19ClO5/c1-2-3-15(10-21(23)24)14-4-7-17(8-5-14)25-12-18-13-26-19-9-6-16(22)11-20(19)27-18/h4-9,11,15,18H,10,12-13H2,1H3,(H,23,24)/t15-,18-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.95E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human OATP1B3 |
Bioorg Med Chem 26: 5780-5791 (2018)
Article DOI: 10.1016/j.bmc.2018.10.019
BindingDB Entry DOI: 10.7270/Q2319ZKH |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50466485
(CHEMBL4288001)Show SMILES CC#C[C@@H](CC(O)=O)c1ccc(OC[C@H]2COc3ccc(Cl)cc3O2)cc1 |r| Show InChI InChI=1S/C21H19ClO5/c1-2-3-15(10-21(23)24)14-4-7-17(8-5-14)25-12-18-13-26-19-9-6-16(22)11-20(19)27-18/h4-9,11,15,18H,10,12-13H2,1H3,(H,23,24)/t15-,18-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human ERG by patch-clamp assay |
Bioorg Med Chem 26: 5780-5791 (2018)
Article DOI: 10.1016/j.bmc.2018.10.019
BindingDB Entry DOI: 10.7270/Q2319ZKH |
More data for this
Ligand-Target Pair | |
Cytochrome P450 2C9
(Homo sapiens (Human)) | BDBM50466485
(CHEMBL4288001)Show SMILES CC#C[C@@H](CC(O)=O)c1ccc(OC[C@H]2COc3ccc(Cl)cc3O2)cc1 |r| Show InChI InChI=1S/C21H19ClO5/c1-2-3-15(10-21(23)24)14-4-7-17(8-5-14)25-12-18-13-26-19-9-6-16(22)11-20(19)27-18/h4-9,11,15,18H,10,12-13H2,1H3,(H,23,24)/t15-,18-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 6.05E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of CYP2C9 (unknown origin) |
Bioorg Med Chem 26: 5780-5791 (2018)
Article DOI: 10.1016/j.bmc.2018.10.019
BindingDB Entry DOI: 10.7270/Q2319ZKH |
More data for this
Ligand-Target Pair | |
Cytochrome P450 2B6
(Homo sapiens (Human)) | BDBM50466485
(CHEMBL4288001)Show SMILES CC#C[C@@H](CC(O)=O)c1ccc(OC[C@H]2COc3ccc(Cl)cc3O2)cc1 |r| Show InChI InChI=1S/C21H19ClO5/c1-2-3-15(10-21(23)24)14-4-7-17(8-5-14)25-12-18-13-26-19-9-6-16(22)11-20(19)27-18/h4-9,11,15,18H,10,12-13H2,1H3,(H,23,24)/t15-,18-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 8.47E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of CYP2B6 (unknown origin) |
Bioorg Med Chem 26: 5780-5791 (2018)
Article DOI: 10.1016/j.bmc.2018.10.019
BindingDB Entry DOI: 10.7270/Q2319ZKH |
More data for this
Ligand-Target Pair | |
Cytochrome P450 3A4
(Homo sapiens (Human)) | BDBM50466485
(CHEMBL4288001)Show SMILES CC#C[C@@H](CC(O)=O)c1ccc(OC[C@H]2COc3ccc(Cl)cc3O2)cc1 |r| Show InChI InChI=1S/C21H19ClO5/c1-2-3-15(10-21(23)24)14-4-7-17(8-5-14)25-12-18-13-26-19-9-6-16(22)11-20(19)27-18/h4-9,11,15,18H,10,12-13H2,1H3,(H,23,24)/t15-,18-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of CYP3A4 (unknown origin) |
Bioorg Med Chem 26: 5780-5791 (2018)
Article DOI: 10.1016/j.bmc.2018.10.019
BindingDB Entry DOI: 10.7270/Q2319ZKH |
More data for this
Ligand-Target Pair | |
Cytochrome P450 2D6
(Homo sapiens (Human)) | BDBM50466485
(CHEMBL4288001)Show SMILES CC#C[C@@H](CC(O)=O)c1ccc(OC[C@H]2COc3ccc(Cl)cc3O2)cc1 |r| Show InChI InChI=1S/C21H19ClO5/c1-2-3-15(10-21(23)24)14-4-7-17(8-5-14)25-12-18-13-26-19-9-6-16(22)11-20(19)27-18/h4-9,11,15,18H,10,12-13H2,1H3,(H,23,24)/t15-,18-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of CYP2D6 (unknown origin) |
Bioorg Med Chem 26: 5780-5791 (2018)
Article DOI: 10.1016/j.bmc.2018.10.019
BindingDB Entry DOI: 10.7270/Q2319ZKH |
More data for this
Ligand-Target Pair | |
Cytochrome P450 1A2
(Homo sapiens (Human)) | BDBM50466485
(CHEMBL4288001)Show SMILES CC#C[C@@H](CC(O)=O)c1ccc(OC[C@H]2COc3ccc(Cl)cc3O2)cc1 |r| Show InChI InChI=1S/C21H19ClO5/c1-2-3-15(10-21(23)24)14-4-7-17(8-5-14)25-12-18-13-26-19-9-6-16(22)11-20(19)27-18/h4-9,11,15,18H,10,12-13H2,1H3,(H,23,24)/t15-,18-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of CYP1A2 (unknown origin) |
Bioorg Med Chem 26: 5780-5791 (2018)
Article DOI: 10.1016/j.bmc.2018.10.019
BindingDB Entry DOI: 10.7270/Q2319ZKH |
More data for this
Ligand-Target Pair | |
ATP-binding cassette sub-family C member 2
(Homo sapiens (Human)) | BDBM50466485
(CHEMBL4288001)Show SMILES CC#C[C@@H](CC(O)=O)c1ccc(OC[C@H]2COc3ccc(Cl)cc3O2)cc1 |r| Show InChI InChI=1S/C21H19ClO5/c1-2-3-15(10-21(23)24)14-4-7-17(8-5-14)25-12-18-13-26-19-9-6-16(22)11-20(19)27-18/h4-9,11,15,18H,10,12-13H2,1H3,(H,23,24)/t15-,18-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human MRP2 |
Bioorg Med Chem 26: 5780-5791 (2018)
Article DOI: 10.1016/j.bmc.2018.10.019
BindingDB Entry DOI: 10.7270/Q2319ZKH |
More data for this
Ligand-Target Pair | |
Solute carrier organic anion transporter family member 1B1
(Homo sapiens (Human)) | BDBM50466485
(CHEMBL4288001)Show SMILES CC#C[C@@H](CC(O)=O)c1ccc(OC[C@H]2COc3ccc(Cl)cc3O2)cc1 |r| Show InChI InChI=1S/C21H19ClO5/c1-2-3-15(10-21(23)24)14-4-7-17(8-5-14)25-12-18-13-26-19-9-6-16(22)11-20(19)27-18/h4-9,11,15,18H,10,12-13H2,1H3,(H,23,24)/t15-,18-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human OATP1BA |
Bioorg Med Chem 26: 5780-5791 (2018)
Article DOI: 10.1016/j.bmc.2018.10.019
BindingDB Entry DOI: 10.7270/Q2319ZKH |
More data for this
Ligand-Target Pair | |
Cytochrome P450 2C19
(Homo sapiens (Human)) | BDBM50466485
(CHEMBL4288001)Show SMILES CC#C[C@@H](CC(O)=O)c1ccc(OC[C@H]2COc3ccc(Cl)cc3O2)cc1 |r| Show InChI InChI=1S/C21H19ClO5/c1-2-3-15(10-21(23)24)14-4-7-17(8-5-14)25-12-18-13-26-19-9-6-16(22)11-20(19)27-18/h4-9,11,15,18H,10,12-13H2,1H3,(H,23,24)/t15-,18-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of CYP2C19 (unknown origin) |
Bioorg Med Chem 26: 5780-5791 (2018)
Article DOI: 10.1016/j.bmc.2018.10.019
BindingDB Entry DOI: 10.7270/Q2319ZKH |
More data for this
Ligand-Target Pair | |
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