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Compile Data Set for Download or QSAR

Found 2 hits of ic50 for monomerid = 50500368   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50500368
PNG
(CHEMBL3746595)
Show SMILES OCc1cc(Oc2ccc3n(ccc3c2)C(=O)Nc2cccc(c2)C(F)(F)F)ncn1
Show InChI InChI=1S/C21H15F3N4O3/c22-21(23,24)14-2-1-3-15(9-14)27-20(30)28-7-6-13-8-17(4-5-18(13)28)31-19-10-16(11-29)25-12-26-19/h1-10,12,29H,11H2,(H,27,30)
PDB
MMDB

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KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4n/an/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Inhibition of Tel-fused KDR (unknown origin) expressed in mouse BaF3 cells using poly(Glu,Tyr) as substrate after 10 mins by scintillation counting a...


J Med Chem 58: 9273-86 (2015)


Article DOI: 10.1021/acs.jmedchem.5b01227
BindingDB Entry DOI: 10.7270/Q26M39T9
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50500368
PNG
(CHEMBL3746595)
Show SMILES OCc1cc(Oc2ccc3n(ccc3c2)C(=O)Nc2cccc(c2)C(F)(F)F)ncn1
Show InChI InChI=1S/C21H15F3N4O3/c22-21(23,24)14-2-1-3-15(9-14)27-20(30)28-7-6-13-8-17(4-5-18(13)28)31-19-10-16(11-29)25-12-26-19/h1-10,12,29H,11H2,(H,27,30)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 13n/an/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Inhibition of KDR (unknown origin)


J Med Chem 58: 9273-86 (2015)


Article DOI: 10.1021/acs.jmedchem.5b01227
BindingDB Entry DOI: 10.7270/Q26M39T9
More data for this
Ligand-Target Pair