Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ATP-sensitive inward rectifier potassium channel 1 (Homo sapiens (Human)) | BDBM50505268 (CHEMBL4549009) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.60 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Nebraska Medical Center Curated by ChEMBL | Assay Description Inhibition of human ROMK1 expressed in CHO cells by Tl+ flux assay | J Med Chem 62: 8682-8694 (2019) Article DOI: 10.1021/acs.jmedchem.8b01891 BindingDB Entry DOI: 10.7270/Q2GH9N7J | |||||||||||
More data for this Ligand-Target Pair |