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Compile Data Set for Download or QSAR

Found 2 hits of ic50 for monomerid = 50506712   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase 10/8/9


(Homo sapiens (Human))
BDBM50506712
PNG
(CHEMBL4583031)
Show SMILES O\N=C1\c2ccccc2-c2nc3cc(Cl)ccc3nc12
Show InChI InChI=1S/C15H8ClN3O/c16-8-5-6-11-12(7-8)18-13-9-3-1-2-4-10(9)14(19-20)15(13)17-11/h1-7,20H/b19-14-
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.20E+3n/an/an/an/an/an/a



Montana State University

Curated by ChEMBL


Assay Description
Inhibition of JNK in human MONO-MAC-6 cells assessed as reduction in LPS-induced IL6 production preincubated for 30 mins followed by LPS-stimulation ...


Eur J Med Chem 161: 179-191 (2019)


Article DOI: 10.1016/j.ejmech.2018.10.023
BindingDB Entry DOI: 10.7270/Q2TB1B58
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 10/8/9


(Homo sapiens (Human))
BDBM50506712
PNG
(CHEMBL4583031)
Show SMILES O\N=C1\c2ccccc2-c2nc3cc(Cl)ccc3nc12
Show InChI InChI=1S/C15H8ClN3O/c16-8-5-6-11-12(7-8)18-13-9-3-1-2-4-10(9)14(19-20)15(13)17-11/h1-7,20H/b19-14-
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.50E+3n/an/an/an/an/an/a



Montana State University

Curated by ChEMBL


Assay Description
Inhibition of JNK in human THP1-Blue cells assessed as reduction in LPS-induced NFkappaB/AP1 activation preincubated for 30 mins followed by LPS-stim...


Eur J Med Chem 161: 179-191 (2019)


Article DOI: 10.1016/j.ejmech.2018.10.023
BindingDB Entry DOI: 10.7270/Q2TB1B58
More data for this
Ligand-Target Pair