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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50508002   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 7


(Homo sapiens (Human))		BDBM50508002
PNG
(CHEMBL4563747)
Show SMILES COc1cc2ncnc(C3CCN(CC3)C(=O)c3ccc(F)cc3)c2cc1OC
Show InChI InChI=1S/C22H22FN3O3/c1-28-19-11-17-18(12-20(19)29-2)24-13-25-21(17)14-7-9-26(10-8-14)22(27)15-3-5-16(23)6-4-15/h3-6,11-14H,7-10H2,1-2H3
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.75E+3n/an/an/an/an/an/a



Bayer AG

Curated by ChEMBL


Assay Description
Inhibition of His-tagged MAP2K5 activated N-terminal GST-tagged recombinant human ERK5 (1 to 398 residues) expressed in Escherichia coli using biotin...

J Med Chem 62: 928-940 (2019)


Article DOI: 10.1021/acs.jmedchem.8b01606
BindingDB Entry DOI: 10.7270/Q2FN19H1
More data for this
Ligand-Target Pair