Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Proteasome subunit beta type-8 (Homo sapiens (Human)) | BDBM50516231 (CHEMBL4536963) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.56E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Weill Cornell Medicine Curated by ChEMBL | Assay Description Inhibition of human beta5 20S immunoproteasome using Ac-ANW-AMC as substrate | J Med Chem 62: 6137-6145 (2019) Article DOI: 10.1021/acs.jmedchem.9b00363 BindingDB Entry DOI: 10.7270/Q2862KTQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteasome subunit beta type-5 (Homo sapiens (Human)) | BDBM50516231 (CHEMBL4536963) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Weill Cornell Medicine Curated by ChEMBL | Assay Description Inhibition of human beta5 20S constitutive proteasome using suc-LLVY-AMC as substrate | J Med Chem 62: 6137-6145 (2019) Article DOI: 10.1021/acs.jmedchem.9b00363 BindingDB Entry DOI: 10.7270/Q2862KTQ | |||||||||||
More data for this Ligand-Target Pair |