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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50516568   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Menin


(Homo sapiens (Human))		BDBM50516568
PNG
(CHEMBL4516680)
Show SMILES CN1Cc2ccccc2C(C1)(C1CCCC1)C1CCN(CC2CN(C2)c2ccc(cc2)S(=O)(=O)c2ccncc2)CC1
Show InChI InChI=1S/C35H44N4O2S/c1-37-25-28-6-2-5-9-34(28)35(26-37,29-7-3-4-8-29)30-16-20-38(21-17-30)22-27-23-39(24-27)31-10-12-32(13-11-31)42(40,41)33-14-18-36-19-15-33/h2,5-6,9-15,18-19,27,29-30H,3-4,7-8,16-17,20-26H2,1H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 11n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay

J Med Chem 62: 6015-6034 (2019)


Article DOI: 10.1021/acs.jmedchem.9b00021
BindingDB Entry DOI: 10.7270/Q2P84G8G
More data for this
Ligand-Target Pair