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Target
Sequence
Name
&
Ki
IC50
Kd
EC50
Rate constants
ΔG°
ΔH°
-TΔS°
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Compile Data Set for Download or QSAR
Found
3
hits of ic50 for monomerid = 50537057
Target/Host
(Institution)
Ligand
Target/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
k
off
s
-1
k
on
M
-1
s
-1
pH
Temp
°C
ATP-dependent RNA helicase DDX3X
(Homo sapiens (Human))
BDBM50537057
(CHEMBL4551611)
Show SMILES
Oc1ccccc1NS(=O)(=O)c1cccc(c1)[N+]([O-])=O
Show InChI
InChI=1S/C12H10N2O5S/c15-12-7-2-1-6-11(12)13-20(18,19)10-5-3-4-9(8-10)14(16)17/h1-8,13,15H
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
Purchase
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
360
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Citation and Details
Article DOI:
10.1021/acs.jmedchem.2c00755
BindingDB Entry DOI:
10.7270/Q29S1W5Q
More data for this
Ligand-Target Pair
ATP-dependent RNA helicase DDX3X
(Homo sapiens (Human))
BDBM50537057
(CHEMBL4551611)
Show SMILES
Oc1ccccc1NS(=O)(=O)c1cccc(c1)[N+]([O-])=O
Show InChI
InChI=1S/C12H10N2O5S/c15-12-7-2-1-6-11(12)13-20(18,19)10-5-3-4-9(8-10)14(16)17/h1-8,13,15H
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
Purchase
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
>2.00E+5
n/a
n/a
n/a
n/a
n/a
n/a
Universit£ degli Studi di Siena
Curated by
ChEMBL
Assay Description
Inhibition of human DDX3X ATPase activity using DDX3 as substrate by ADP-Glo kinase assay
J Med Chem
62:
2333
-
2347
(2019)
Article DOI:
10.1021/acs.jmedchem.8b01403
BindingDB Entry DOI:
10.7270/Q2X06BJK
More data for this
Ligand-Target Pair
ATP-dependent RNA helicase DDX1
(Homo sapiens (Human))
BDBM50537057
(CHEMBL4551611)
Show SMILES
Oc1ccccc1NS(=O)(=O)c1cccc(c1)[N+]([O-])=O
Show InChI
InChI=1S/C12H10N2O5S/c15-12-7-2-1-6-11(12)13-20(18,19)10-5-3-4-9(8-10)14(16)17/h1-8,13,15H
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
Purchase
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
>2.00E+5
n/a
n/a
n/a
n/a
n/a
n/a
Universit£ degli Studi di Siena
Curated by
ChEMBL
Assay Description
Inhibition of human DDX1 helicase activity
J Med Chem
62:
2333
-
2347
(2019)
Article DOI:
10.1021/acs.jmedchem.8b01403
BindingDB Entry DOI:
10.7270/Q2X06BJK
More data for this
Ligand-Target Pair