Compile Data Set for Download or QSAR

Found 3 hits of ic50 for monomerid = 50537721   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50537721 (CHEMBL4646478 | US11230547, Compound 1-17) Show SMILES [H][C@]12CN(c3nc(ncc3C#N)-c3ccnc4[nH]ccc34)[C@]([H])(CN1c1cccc(F)c1)C2 |r| Show InChI InChI=1S/C23H18FN7/c24-15-2-1-3-16(8-15)30-12-18-9-17(30)13-31(18)23-14(10-25)11-28-22(29-23)20-5-7-27-21-19(20)4-6-26-21/h1-8,11,17-18H,9,12-13H2,(H,26,27)/t17-,18-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Inhibition of recombinant human full-length N-terminal GST-tagged p110delta/untagged full-length p85alpha expressed in baculovirus infected Sf21 cell...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126715 BindingDB Entry DOI: 10.7270/Q2HM5CZG
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50537721 (CHEMBL4646478 | US11230547, Compound 1-17) Show SMILES [H][C@]12CN(c3nc(ncc3C#N)-c3ccnc4[nH]ccc34)[C@]([H])(CN1c1cccc(F)c1)C2 |r| Show InChI InChI=1S/C23H18FN7/c24-15-2-1-3-16(8-15)30-12-18-9-17(30)13-31(18)23-14(10-25)11-28-22(29-23)20-5-7-27-21-19(20)4-6-26-21/h1-8,11,17-18H,9,12-13H2,(H,26,27)/t17-,18-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description This assay was developed and further optimized from a kit produced by Upstate (Millipore catalog #33-047) (Millipore Sigma, Billerica Mass., USA) and...				Citation and Details BindingDB Entry DOI: 10.7270/Q2K35XTR
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50537721 (CHEMBL4646478 | US11230547, Compound 1-17) Show SMILES [H][C@]12CN(c3nc(ncc3C#N)-c3ccnc4[nH]ccc34)[C@]([H])(CN1c1cccc(F)c1)C2 |r| Show InChI InChI=1S/C23H18FN7/c24-15-2-1-3-16(8-15)30-12-18-9-17(30)13-31(18)23-14(10-25)11-28-22(29-23)20-5-7-27-21-19(20)4-6-26-21/h1-8,11,17-18H,9,12-13H2,(H,26,27)/t17-,18-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Inhibition of the fibroblast growth factor receptor (FGFR1)				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126715 BindingDB Entry DOI: 10.7270/Q2HM5CZG
					More data for this Ligand-Target Pair