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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50538463   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase SYK


(Homo sapiens (Human))		BDBM50538463
PNG
(CHEMBL4647318)
Show SMILES C1OCC1N1CCN(CC1)c1ccc(Nc2nc(cn3ccnc23)-c2ccc3nc[nH]c3n2)cc1
Show InChI InChI=1S/C25H25N9O/c1-3-18(32-9-11-33(12-10-32)19-14-35-15-19)4-2-17(1)29-24-25-26-7-8-34(25)13-22(31-24)20-5-6-21-23(30-20)28-16-27-21/h1-8,13,16,19H,9-12,14-15H2,(H,29,31)(H,27,28,30)
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 32n/an/an/an/an/an/a



Gilead Sciences

Curated by ChEMBL


Assay Description
Inhibition of SYK (unknown origin) using XL665-labeled peptide as substrate in presence of ATP measured after 30 mins by TR-FRET assay

ACS Med Chem Lett 11: 506-513 (2020)


Article DOI: 10.1021/acsmedchemlett.9b00621
BindingDB Entry DOI: 10.7270/Q2ZG6WR1
More data for this
Ligand-Target Pair