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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50544528   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily M member 8


(Rattus norvegicus (Rat))		BDBM50544528
PNG
(CHEMBL4637481)
Show SMILES [H][C@]12Cc3c([nH]c4ccccc34)[C@@H](N1C(=O)N(CCCN)C2=O)c1ccc(F)cc1 |r|
Show InChI InChI=1S/C22H21FN4O2/c23-14-8-6-13(7-9-14)20-19-16(15-4-1-2-5-17(15)25-19)12-18-21(28)26(11-3-10-24)22(29)27(18)20/h1-2,4-9,18,20,25H,3,10-12,24H2/t18-,20+/m1/s1
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.72E+4n/an/an/an/an/an/a



University of Salerno

Curated by ChEMBL


Assay Description
Antagonist activity at rat TRPM8 expressed in HEK293 cells assessed as inhibition of menthol-induced calcium flux preincubated for 60 mins followed b...

J Med Chem 63: 9672-9694 (2020)


Article DOI: 10.1021/acs.jmedchem.0c00816
BindingDB Entry DOI: 10.7270/Q2GF0Z2X
More data for this
Ligand-Target Pair