Compile Data Set for Download or QSAR

Found 3 hits of ic50 for monomerid = 99436   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99436 (US8497281, 147 | US9120769, 147 | US9663470, 147) Show SMILES O=C(N1CCCC2[C@@H]1Cc1ccccc21)c1ccc2[nH]c(=O)cnc2c1 |r| Show InChI InChI=1S/C21H19N3O2/c25-20-12-22-18-10-14(7-8-17(18)23-20)21(26)24-9-3-6-16-15-5-2-1-4-13(15)11-19(16)24/h1-2,4-5,7-8,10,12,16,19H,3,6,9,11H2,(H,23,25)/t16?,19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.74E+3	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99436 (US8497281, 147 | US9120769, 147 | US9663470, 147) Show SMILES O=C(N1CCCC2[C@@H]1Cc1ccccc21)c1ccc2[nH]c(=O)cnc2c1 |r| Show InChI InChI=1S/C21H19N3O2/c25-20-12-22-18-10-14(7-8-17(18)23-20)21(26)24-9-3-6-16-15-5-2-1-4-13(15)11-19(16)24/h1-2,4-5,7-8,10,12,16,19H,3,6,9,11H2,(H,23,25)/t16?,19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.74E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International Gmbh US Patent					Assay Description In vitro inhibition of 11β-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluorescence) technology (cisbio internatio...				US Patent US9663470 (2017) BindingDB Entry DOI: 10.7270/Q2V40X8H
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99436 (US8497281, 147 | US9120769, 147 | US9663470, 147) Show SMILES O=C(N1CCCC2[C@@H]1Cc1ccccc21)c1ccc2[nH]c(=O)cnc2c1 |r| Show InChI InChI=1S/C21H19N3O2/c25-20-12-22-18-10-14(7-8-17(18)23-20)21(26)24-9-3-6-16-15-5-2-1-4-13(15)11-19(16)24/h1-2,4-5,7-8,10,12,16,19H,3,6,9,11H2,(H,23,25)/t16?,19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.74E+3	n/a	n/a	n/a	n/a	6.0	n/a
Boehringer-Ingelheim International GmbH US Patent					Assay Description n vitro inhibition of 11β-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluorescence) technology (cisbio internation...				US Patent US9120769 (2015) BindingDB Entry DOI: 10.7270/Q2XW4HK9
					More data for this Ligand-Target Pair