Compile Data Set for Download or QSAR

Found 203 hits of ic50 for UniProtKB: P00390   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50176071 (2-(2-Amino-ethylamino)-N-(7-{2-[N'-(5-nitro-furan-...) Show SMILES [O-][N+](=O)c1ccc(o1)C(=O)NNC(=O)Cc1ccc2ccc(NC(=O)C[NH+]3CC[NH2+][Pt]3(Cl)Cl)cc2c1 Show InChI InChI=1S/C21H22N6O6.2ClH.Pt/c22-7-8-23-12-19(29)24-16-4-3-14-2-1-13(9-15(14)11-16)10-18(28)25-26-21(30)17-5-6-20(33-17)27(31)32;;;/h1-6,9,11,23H,7-8,10,12,22H2,(H,24,29)(H,25,28)(H,26,30);2*1H;/q;;;+4/p-2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
UMR 8525 CNRS-Université Lille II-Institut Pasteur de Lille Curated by ChEMBL					Assay Description Inhibitory concentration against human glutathione reductase				J Med Chem 48: 7024-39 (2005) Article DOI: 10.1021/jm050256l BindingDB Entry DOI: 10.7270/Q2CN73F9
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50121447 (5-Nitro-furan-2-carboxylic acid N'-(2-naphthalen-2...) Show SMILES [O-][N+](=O)c1ccc(o1)C(=O)NNC(=O)Cc1ccc2ccccc2c1 Show InChI InChI=1S/C17H13N3O5/c21-15(10-11-5-6-12-3-1-2-4-13(12)9-11)18-19-17(22)14-7-8-16(25-14)20(23)24/h1-9H,10H2,(H,18,21)(H,19,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
UMR 8525 CNRS-Université Lille II-Institut Pasteur de Lille Curated by ChEMBL					Assay Description Inhibitory concentration against human glutathione reductase				J Med Chem 48: 7024-39 (2005) Article DOI: 10.1021/jm050256l BindingDB Entry DOI: 10.7270/Q2CN73F9
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50352164 (CHEMBL1824793) Show SMILES OC(=O)CC[C@H](NC(=O)c1ccc(cc1)[N+]([O-])=O)C(O)=O |r| Show InChI InChI=1S/C12H12N2O7/c15-10(16)6-5-9(12(18)19)13-11(17)7-1-3-8(4-2-7)14(20)21/h1-4,9H,5-6H2,(H,13,17)(H,15,16)(H,18,19)/t9-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	344	n/a	n/a	n/a	n/a	n/a	n/a
Batman University Curated by ChEMBL					Assay Description Inhibition of human erythrocyte Glutathione reductase				Bioorg Med Chem Lett 21: 5398-402 (2011) Article DOI: 10.1016/j.bmcl.2011.07.002 BindingDB Entry DOI: 10.7270/Q2V69KKH
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50096018 (6-(3-METHYL-1,4-DIOXO-1,4-DIHYDRONAPHTHALEN-2-YL)H...) Show SMILES Cc1c(O)c2ccccc2c(O)c1C=CCCCC(O)=O |w:14.16| Show InChI InChI=1S/C17H18O4/c1-11-12(7-3-2-4-10-15(18)19)17(21)14-9-6-5-8-13(14)16(11)20/h3,5-9,20-21H,2,4,10H2,1H3,(H,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
UMR 8525 CNRS-Université Lille II-Institut Pasteur de Lille Curated by ChEMBL					Assay Description In vitro inhibition of Plasmodium falciparum Glutathione Reductase				J Med Chem 44: 4268-76 (2001) BindingDB Entry DOI: 10.7270/Q20V8C2Q
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50096035 (6-(8-Hydroxy-3-methyl-1,4-dioxo-1,4-dihydro-naphth...) Show SMILES Cc1c(O)c2cccc(O)c2c(O)c1C=CCCCC(O)=O |w:15.17| Show InChI InChI=1S/C17H18O5/c1-10-11(6-3-2-4-9-14(19)20)17(22)15-12(16(10)21)7-5-8-13(15)18/h3,5-8,18,21-22H,2,4,9H2,1H3,(H,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	750	n/a	n/a	n/a	n/a	n/a	n/a
UMR 8525 CNRS-Université Lille II-Institut Pasteur de Lille Curated by ChEMBL					Assay Description In vitro inhibition of human Glutathione Reductase				J Med Chem 44: 4268-76 (2001) BindingDB Entry DOI: 10.7270/Q20V8C2Q
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50052014 (3-Methyl-10-(3-trifluoromethyl-phenyl)-10H-benzo[g...) Show SMILES Cn1c(=O)nc2n(-c3cccc(c3)C(F)(F)F)c3ccccc3nc2c1=O Show InChI InChI=1S/C18H11F3N4O2/c1-24-16(26)14-15(23-17(24)27)25(13-8-3-2-7-12(13)22-14)11-6-4-5-10(9-11)18(19,20)21/h2-9H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institut für Biochemie II der Universität Curated by ChEMBL					Assay Description Inhibitory activity against human glutathione reductase in presence of 100 microM GSSG				J Med Chem 39: 1549-54 (1996) Article DOI: 10.1021/jm950511+ BindingDB Entry DOI: 10.7270/Q2F18XTZ
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50052000 (10-(3-Trifluoromethyl-phenyl)-10H-benzo[g]pteridin...) Show SMILES FC(F)(F)c1cccc(c1)-n1c2ccccc2nc2c1nc(=O)[nH]c2=O Show InChI InChI=1S/C17H9F3N4O2/c18-17(19,20)9-4-3-5-10(8-9)24-12-7-2-1-6-11(12)21-13-14(24)22-16(26)23-15(13)25/h1-8H,(H,23,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institut für Biochemie II der Universität Curated by ChEMBL					Assay Description Inhibitory activity against human glutathione reductase in presence of 100 microM GSSG				J Med Chem 39: 1549-54 (1996) Article DOI: 10.1021/jm950511+ BindingDB Entry DOI: 10.7270/Q2F18XTZ
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50096062 (5-(8-Hydroxy-3-methyl-1,4-dioxo-1,4-dihydro-naphth...) Show SMILES Cc1c(O)c2cccc(O)c2c(O)c1C=CCCC(O)=O |w:15.17| Show InChI InChI=1S/C16H16O5/c1-9-10(5-2-3-8-13(18)19)16(21)14-11(15(9)20)6-4-7-12(14)17/h2,4-7,17,20-21H,3,8H2,1H3,(H,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
UMR 8525 CNRS-Université Lille II-Institut Pasteur de Lille Curated by ChEMBL					Assay Description In vitro inhibition of human Glutathione Reductase				J Med Chem 44: 4268-76 (2001) BindingDB Entry DOI: 10.7270/Q20V8C2Q
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50051997 (10-(4-Chloro-phenyl)-8-fluoro-3-methyl-10H-benzo[g...) Show SMILES Cn1c(=O)nc2n(-c3ccc(Cl)cc3)c3cc(F)ccc3nc2c1=O Show InChI InChI=1S/C17H10ClFN4O2/c1-22-16(24)14-15(21-17(22)25)23(11-5-2-9(18)3-6-11)13-8-10(19)4-7-12(13)20-14/h2-8H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institut für Biochemie II der Universität Curated by ChEMBL					Assay Description Inhibitory activity against human glutathione reductase in presence of 100 microM GSSG				J Med Chem 39: 1549-54 (1996) Article DOI: 10.1021/jm950511+ BindingDB Entry DOI: 10.7270/Q2F18XTZ
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50096035 (6-(8-Hydroxy-3-methyl-1,4-dioxo-1,4-dihydro-naphth...) Show SMILES Cc1c(O)c2cccc(O)c2c(O)c1C=CCCCC(O)=O |w:15.17| Show InChI InChI=1S/C17H18O5/c1-10-11(6-3-2-4-9-14(19)20)17(22)15-12(16(10)21)7-5-8-13(15)18/h3,5-8,18,21-22H,2,4,9H2,1H3,(H,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
UMR 8525 CNRS-Université Lille II-Institut Pasteur de Lille Curated by ChEMBL					Assay Description In vitro inhibition of Plasmodium falciparum Glutathione Reductase				J Med Chem 44: 4268-76 (2001) BindingDB Entry DOI: 10.7270/Q20V8C2Q
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50051998 (3-Methyl-10-naphthalen-1-yl-10H-benzo[g]pteridine-...) Show SMILES Cn1c(=O)nc2n(-c3cccc4ccccc34)c3ccccc3nc2c1=O |(6.46,-6.99,;5.11,-6.23,;5.1,-4.68,;6.43,-3.89,;3.76,-3.92,;2.42,-4.69,;1.09,-3.95,;1.07,-2.41,;-.26,-1.65,;-.28,-.11,;1.06,.66,;2.41,-.08,;3.7,.67,;5.05,-.08,;5.05,-1.61,;3.73,-2.38,;2.41,-1.61,;-.25,-4.73,;-1.57,-3.96,;-2.91,-4.73,;-2.91,-6.27,;-1.57,-7.04,;-.25,-6.27,;1.1,-7.04,;2.44,-6.26,;3.79,-7.03,;3.8,-8.57,)| Show InChI InChI=1S/C21H14N4O2/c1-24-20(26)18-19(23-21(24)27)25(17-11-5-4-10-15(17)22-18)16-12-6-8-13-7-2-3-9-14(13)16/h2-12H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institut für Biochemie II der Universität Curated by ChEMBL					Assay Description Inhibitory activity against human glutathione reductase in presence of 100 microM GSSG				J Med Chem 39: 1549-54 (1996) Article DOI: 10.1021/jm950511+ BindingDB Entry DOI: 10.7270/Q2F18XTZ
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50052004 (3-Methyl-10-phenyl-10H-benzo[g]pteridine-2,4-dione...) Show SMILES Cn1c(=O)nc2n(-c3ccccc3)c3ccccc3nc2c1=O Show InChI InChI=1S/C17H12N4O2/c1-20-16(22)14-15(19-17(20)23)21(11-7-3-2-4-8-11)13-10-6-5-9-12(13)18-14/h2-10H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institut für Biochemie II der Universität Curated by ChEMBL					Assay Description Inhibitory activity against human glutathione reductase in presence of 100 microM GSSG				J Med Chem 39: 1549-54 (1996) Article DOI: 10.1021/jm950511+ BindingDB Entry DOI: 10.7270/Q2F18XTZ
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50052001 (8-Azido-10-(4-chloro-phenyl)-3-methyl-10H-benzo[g]...) Show SMILES Cn1c(=O)nc2n(-c3ccc(Cl)cc3)c3cc(ccc3nc2c1=O)N=[N+]=[N-] Show InChI InChI=1S/C17H10ClN7O2/c1-24-16(26)14-15(21-17(24)27)25(11-5-2-9(18)3-6-11)13-8-10(22-23-19)4-7-12(13)20-14/h2-8H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institut für Biochemie II der Universität Curated by ChEMBL					Assay Description Inhibitory activity against human glutathione reductase in presence of 100 microM GSSG				J Med Chem 39: 1549-54 (1996) Article DOI: 10.1021/jm950511+ BindingDB Entry DOI: 10.7270/Q2F18XTZ
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50096062 (5-(8-Hydroxy-3-methyl-1,4-dioxo-1,4-dihydro-naphth...) Show SMILES Cc1c(O)c2cccc(O)c2c(O)c1C=CCCC(O)=O |w:15.17| Show InChI InChI=1S/C16H16O5/c1-9-10(5-2-3-8-13(18)19)16(21)14-11(15(9)20)6-4-7-12(14)17/h2,4-7,17,20-21H,3,8H2,1H3,(H,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
UMR 8525 CNRS-Université Lille II-Institut Pasteur de Lille Curated by ChEMBL					Assay Description In vitro inhibition of Plasmodium falciparum Glutathione Reductase				J Med Chem 44: 4268-76 (2001) BindingDB Entry DOI: 10.7270/Q20V8C2Q
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50096018 (6-(3-METHYL-1,4-DIOXO-1,4-DIHYDRONAPHTHALEN-2-YL)H...) Show SMILES Cc1c(O)c2ccccc2c(O)c1C=CCCCC(O)=O |w:14.16| Show InChI InChI=1S/C17H18O4/c1-11-12(7-3-2-4-10-15(18)19)17(21)14-9-6-5-8-13(14)16(11)20/h3,5-9,20-21H,2,4,10H2,1H3,(H,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
UMR 8525 CNRS-Université Lille II-Institut Pasteur de Lille Curated by ChEMBL					Assay Description In vitro inhibition of human Glutathione Reductase				J Med Chem 44: 4268-76 (2001) BindingDB Entry DOI: 10.7270/Q20V8C2Q
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50096018 (6-(3-METHYL-1,4-DIOXO-1,4-DIHYDRONAPHTHALEN-2-YL)H...) Show SMILES Cc1c(O)c2ccccc2c(O)c1C=CCCCC(O)=O |w:14.16| Show InChI InChI=1S/C17H18O4/c1-11-12(7-3-2-4-10-15(18)19)17(21)14-9-6-5-8-13(14)16(11)20/h3,5-9,20-21H,2,4,10H2,1H3,(H,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université Libre de Bruxelles Curated by ChEMBL					Assay Description Inhibitory concentration against human glutathione reductase in the absence of glucose-6-phosphate dehydrogenase (G6PDH)				J Med Chem 47: 5972-83 (2004) Article DOI: 10.1021/jm0497545 BindingDB Entry DOI: 10.7270/Q20R9NW4
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50096018 (6-(3-METHYL-1,4-DIOXO-1,4-DIHYDRONAPHTHALEN-2-YL)H...) Show SMILES Cc1c(O)c2ccccc2c(O)c1C=CCCCC(O)=O |w:14.16| Show InChI InChI=1S/C17H18O4/c1-11-12(7-3-2-4-10-15(18)19)17(21)14-9-6-5-8-13(14)16(11)20/h3,5-9,20-21H,2,4,10H2,1H3,(H,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université Libre de Bruxelles Curated by ChEMBL					Assay Description Inhibitory concentration against human glutathione reductase in the the presence of 200 uM exogenous NADP				J Med Chem 47: 5972-83 (2004) Article DOI: 10.1021/jm0497545 BindingDB Entry DOI: 10.7270/Q20R9NW4
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50096071 (5-(3-Methyl-1,4-dioxo-1,4-dihydro-naphthalen-2-yl)...) Show SMILES Cc1c(O)c2ccccc2c(O)c1C=CCCC(O)=O |w:14.16| Show InChI InChI=1S/C16H16O4/c1-10-11(6-4-5-9-14(17)18)16(20)13-8-3-2-7-12(13)15(10)19/h2-4,6-8,19-20H,5,9H2,1H3,(H,17,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
UMR 8525 CNRS-Université Lille II-Institut Pasteur de Lille Curated by ChEMBL					Assay Description In vitro inhibition of human Glutathione Reductase				J Med Chem 44: 4268-76 (2001) BindingDB Entry DOI: 10.7270/Q20V8C2Q
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50096018 (6-(3-METHYL-1,4-DIOXO-1,4-DIHYDRONAPHTHALEN-2-YL)H...) Show SMILES Cc1c(O)c2ccccc2c(O)c1C=CCCCC(O)=O |w:14.16| Show InChI InChI=1S/C17H18O4/c1-11-12(7-3-2-4-10-15(18)19)17(21)14-9-6-5-8-13(14)16(11)20/h3,5-9,20-21H,2,4,10H2,1H3,(H,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université Libre de Bruxelles Curated by ChEMBL					Assay Description Inhibitory concentration against human glutathione reductase in the the presence of 200 uM exogenous NADP				J Med Chem 47: 5972-83 (2004) Article DOI: 10.1021/jm0497545 BindingDB Entry DOI: 10.7270/Q20R9NW4
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50051996 (3-Methyl-10-pyridin-4-yl-10H-benzo[g]pteridine-2,4...) Show SMILES Cn1c(=O)nc2n(-c3ccncc3)c3ccccc3nc2c1=O Show InChI InChI=1S/C16H11N5O2/c1-20-15(22)13-14(19-16(20)23)21(10-6-8-17-9-7-10)12-5-3-2-4-11(12)18-13/h2-9H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institut für Biochemie II der Universität Curated by ChEMBL					Assay Description Inhibitory activity against human glutathione reductase in presence of 100 microM GSSG				J Med Chem 39: 1549-54 (1996) Article DOI: 10.1021/jm950511+ BindingDB Entry DOI: 10.7270/Q2F18XTZ
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50096018 (6-(3-METHYL-1,4-DIOXO-1,4-DIHYDRONAPHTHALEN-2-YL)H...) Show SMILES Cc1c(O)c2ccccc2c(O)c1C=CCCCC(O)=O |w:14.16| Show InChI InChI=1S/C17H18O4/c1-11-12(7-3-2-4-10-15(18)19)17(21)14-9-6-5-8-13(14)16(11)20/h3,5-9,20-21H,2,4,10H2,1H3,(H,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université Libre de Bruxelles Curated by ChEMBL					Assay Description Inhibitory concentration against human glutathione reductase				J Med Chem 47: 5972-83 (2004) Article DOI: 10.1021/jm0497545 BindingDB Entry DOI: 10.7270/Q20R9NW4
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50052006 (10-Pentafluorophenyl-10H-benzo[g]pteridine-2,4-dio...) Show SMILES Fc1c(F)c(F)c(c(F)c1F)-n1c2ccccc2nc2c1nc(=O)[nH]c2=O |(1.04,2.2,;1.06,.66,;2.4,-.07,;3.73,.69,;2.4,-1.63,;3.73,-2.4,;1.07,-2.4,;-.26,-1.65,;-1.59,-2.44,;-.28,-.11,;-1.62,.63,;1.09,-3.94,;-.25,-4.72,;-1.57,-3.95,;-2.91,-4.72,;-2.91,-6.26,;-1.57,-7.03,;-.25,-6.26,;1.1,-7.03,;2.44,-6.25,;2.41,-4.69,;3.76,-3.92,;5.1,-4.68,;6.42,-3.89,;5.11,-6.23,;3.78,-7.02,;3.79,-8.56,)| Show InChI InChI=1S/C16H5F5N4O2/c17-7-8(18)10(20)13(11(21)9(7)19)25-6-4-2-1-3-5(6)22-12-14(25)23-16(27)24-15(12)26/h1-4H,(H,24,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institut für Biochemie II der Universität Curated by ChEMBL					Assay Description Inhibitory activity against human glutathione reductase in presence of 100 microM GSSG				J Med Chem 39: 1549-54 (1996) Article DOI: 10.1021/jm950511+ BindingDB Entry DOI: 10.7270/Q2F18XTZ
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50052007 (10-(3,5-Bis-trifluoromethyl-phenyl)-10H-benzo[g]pt...) Show SMILES FC(F)(F)c1cc(cc(c1)C(F)(F)F)-n1c2ccccc2nc2c1nc(=O)[nH]c2=O Show InChI InChI=1S/C18H8F6N4O2/c19-17(20,21)8-5-9(18(22,23)24)7-10(6-8)28-12-4-2-1-3-11(12)25-13-14(28)26-16(30)27-15(13)29/h1-7H,(H,27,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institut für Biochemie II der Universität Curated by ChEMBL					Assay Description Inhibitory activity against human glutathione reductase in presence of 100 microM GSSG				J Med Chem 39: 1549-54 (1996) Article DOI: 10.1021/jm950511+ BindingDB Entry DOI: 10.7270/Q2F18XTZ
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50051994 (10-Anthracen-1-yl-3-methyl-10H-benzo[g]pteridine-2...) Show SMILES Cn1c(=O)nc2n(-c3cccc4cc5ccccc5cc34)c3ccccc3nc2c1=O |(19.16,-12.07,;17.82,-11.33,;17.81,-9.76,;19.13,-8.98,;16.47,-9.02,;15.12,-9.79,;13.8,-9.03,;13.77,-7.52,;15.09,-6.75,;15.09,-5.21,;13.74,-4.46,;12.45,-5.21,;11.1,-4.47,;9.76,-5.26,;8.45,-4.5,;7.12,-5.27,;7.13,-6.81,;8.47,-7.57,;9.79,-6.78,;11.11,-7.54,;12.45,-6.75,;12.46,-9.82,;11.13,-9.05,;9.8,-9.82,;9.8,-11.36,;11.13,-12.13,;12.46,-11.36,;13.81,-12.13,;15.14,-11.34,;16.49,-12.11,;16.5,-13.65,)| Show InChI InChI=1S/C25H16N4O2/c1-28-24(30)22-23(27-25(28)31)29(21-11-5-4-10-19(21)26-22)20-12-6-9-17-13-15-7-2-3-8-16(15)14-18(17)20/h2-14H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institut für Biochemie II der Universität Curated by ChEMBL					Assay Description Inhibitory activity against human glutathione reductase in presence of 100 microM GSSG				J Med Chem 39: 1549-54 (1996) Article DOI: 10.1021/jm950511+ BindingDB Entry DOI: 10.7270/Q2F18XTZ
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50096071 (5-(3-Methyl-1,4-dioxo-1,4-dihydro-naphthalen-2-yl)...) Show SMILES Cc1c(O)c2ccccc2c(O)c1C=CCCC(O)=O |w:14.16| Show InChI InChI=1S/C16H16O4/c1-10-11(6-4-5-9-14(17)18)16(20)13-8-3-2-7-12(13)15(10)19/h2-4,6-8,19-20H,5,9H2,1H3,(H,17,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
UMR 8525 CNRS-Université Lille II-Institut Pasteur de Lille Curated by ChEMBL					Assay Description In vitro inhibition of Plasmodium falciparum Glutathione Reductase				J Med Chem 44: 4268-76 (2001) BindingDB Entry DOI: 10.7270/Q20V8C2Q
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50052010 (10-(3,5-Bis-trifluoromethyl-phenyl)-3-methyl-10H-b...) Show SMILES Cn1c(=O)nc2n(-c3cc(cc(c3)C(F)(F)F)C(F)(F)F)c3ccccc3nc2c1=O Show InChI InChI=1S/C19H10F6N4O2/c1-28-16(30)14-15(27-17(28)31)29(13-5-3-2-4-12(13)26-14)11-7-9(18(20,21)22)6-10(8-11)19(23,24)25/h2-8H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institut für Biochemie II der Universität Curated by ChEMBL					Assay Description Inhibitory activity against human glutathione reductase in presence of 100 microM GSSG				J Med Chem 39: 1549-54 (1996) Article DOI: 10.1021/jm950511+ BindingDB Entry DOI: 10.7270/Q2F18XTZ
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50177103 (1-(2'-chlorophenyl)penta-1,4-dien-3-one | CHEMBL22...) Show SMILES Clc1ccccc1\C=C\C(=O)C=C Show InChI InChI=1S/C11H9ClO/c1-2-10(13)8-7-9-5-3-4-6-11(9)12/h2-8H,1H2/b8-7+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Biochemie-Zentrum der Universität Heidelberg Curated by ChEMBL					Assay Description Inhibition of human glutathione reductase after 5 mins preincubation with NADPH in presence of 500 uM GSSG substrate				J Med Chem 48: 7400-10 (2005) Article DOI: 10.1021/jm0504860 BindingDB Entry DOI: 10.7270/Q23X8662
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50316592 ((2R(S),7R(S))-7-Hydroxybicyclo[2.2.1]heptan-2-yl n...) Show SMILES O[C@@H]1C2CCC1[C@@H](C2)O[N+]([O-])=O |r,THB:0:1:4.3:7.6| Show InChI InChI=1S/C7H11NO4/c9-7-4-1-2-5(7)6(3-4)12-8(10)11/h4-7,9H,1-3H2/t4?,5?,6-,7-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.81E+3	n/a	n/a	n/a	n/a	n/a	n/a
Atat£rk University Curated by ChEMBL					Assay Description Inhibition of human erythrocyte glutathione reductase				Bioorg Med Chem Lett 19: 3661-3 (2009) Article DOI: 10.1016/j.bmcl.2009.04.087 BindingDB Entry DOI: 10.7270/Q2930V34
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50052013 (CHEMBL415870 | [10-(3,5-Dichloro-phenyl)-2,4-dioxo...) Show SMILES CCOC(=O)Cn1c(=O)nc2n(-c3cc(Cl)cc(Cl)c3)c3ccccc3nc2c1=O Show InChI InChI=1S/C20H14Cl2N4O4/c1-2-30-16(27)10-25-19(28)17-18(24-20(25)29)26(13-8-11(21)7-12(22)9-13)15-6-4-3-5-14(15)23-17/h3-9H,2,10H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institut für Biochemie II der Universität Curated by ChEMBL					Assay Description Inhibitory activity against human glutathione reductase in presence of 100 microM GSSG				J Med Chem 39: 1549-54 (1996) Article DOI: 10.1021/jm950511+ BindingDB Entry DOI: 10.7270/Q2F18XTZ
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50293668 ((2S(R),7R(S))-7-Hydroxybicyclo[2.2.1]heptan-2-yl n...) Show SMILES OC1C2CCC1C(C2)O[N+]([O-])=O |TLB:8:6:3.4:1,THB:0:1:3.4:6.7| Show InChI InChI=1S/C7H11NO4/c9-7-4-1-2-5(7)6(3-4)12-8(10)11/h4-7,9H,1-3H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.13E+3	n/a	n/a	n/a	n/a	n/a	n/a
Atat£rk University Curated by ChEMBL					Assay Description Inhibition of human erythrocyte glutathione reductase				Bioorg Med Chem Lett 19: 3661-3 (2009) Article DOI: 10.1016/j.bmcl.2009.04.087 BindingDB Entry DOI: 10.7270/Q2930V34
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50293667 ((1R(S),2R(S),3S(R),4S(R))-2,3-Dihydroxycyclo-hexan...) Show SMILES OC1C(O)C(CCC1O[N+]([O-])=O)O[N+]([O-])=O Show InChI InChI=1S/C6H10N2O8/c9-5-3(15-7(11)12)1-2-4(6(5)10)16-8(13)14/h3-6,9-10H,1-2H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.17E+3	n/a	n/a	n/a	n/a	n/a	n/a
Atat£rk University Curated by ChEMBL					Assay Description Inhibition of human erythrocyte glutathione reductase				Bioorg Med Chem Lett 19: 3661-3 (2009) Article DOI: 10.1016/j.bmcl.2009.04.087 BindingDB Entry DOI: 10.7270/Q2930V34
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50339129 (CHEMBL1688544 | Coruleoellagic acid) Show SMILES Oc1c(O)c2oc(=O)c3c(O)c(O)c(O)c4oc(=O)c(c1O)c2c34 Show InChI InChI=1S/C14H6O10/c15-5-3-1-2-4(14(22)23-11(1)9(19)7(5)17)6(16)8(18)10(20)12(2)24-13(3)21/h15-20H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Justus-Liebig-University Curated by ChEMBL					Assay Description Inhibition of human glutathione reductase by spectrophotometer				Antimicrob Agents Chemother 53: 622-30 (2009) Article DOI: 10.1128/AAC.00544-08 BindingDB Entry DOI: 10.7270/Q2RR1ZJ5
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50052011 (CHEMBL38563 | [2,4-Dioxo-10-(3-trifluoromethyl-phe...) Show SMILES CCOC(=O)Cn1c(=O)nc2n(-c3cccc(c3)C(F)(F)F)c3ccccc3nc2c1=O Show InChI InChI=1S/C21H15F3N4O4/c1-2-32-16(29)11-27-19(30)17-18(26-20(27)31)28(15-9-4-3-8-14(15)25-17)13-7-5-6-12(10-13)21(22,23)24/h3-10H,2,11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institut für Biochemie II der Universität Curated by ChEMBL					Assay Description Inhibitory activity against human glutathione reductase in presence of 100 microM GSSG				J Med Chem 39: 1549-54 (1996) Article DOI: 10.1021/jm950511+ BindingDB Entry DOI: 10.7270/Q2F18XTZ
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50052002 (3-Methyl-10-pyridin-3-yl-10H-benzo[g]pteridine-2,4...) Show SMILES Cn1c(=O)nc2n(-c3cccnc3)c3ccccc3nc2c1=O Show InChI InChI=1S/C16H11N5O2/c1-20-15(22)13-14(19-16(20)23)21(10-5-4-8-17-9-10)12-7-3-2-6-11(12)18-13/h2-9H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institut für Biochemie II der Universität Curated by ChEMBL					Assay Description Inhibitory activity against human glutathione reductase in presence of 100 microM GSSG				J Med Chem 39: 1549-54 (1996) Article DOI: 10.1021/jm950511+ BindingDB Entry DOI: 10.7270/Q2F18XTZ
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50293666 ((1S(R),3S(R),4S(R),6S(R))-4,6-Dihydroxycyclo-hexan...) Show SMILES OC1CC(O)C(CC1O[N+]([O-])=O)O[N+]([O-])=O Show InChI InChI=1S/C6H10N2O8/c9-3-1-4(10)6(16-8(13)14)2-5(3)15-7(11)12/h3-6,9-10H,1-2H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Atat£rk University Curated by ChEMBL					Assay Description Inhibition of human erythrocyte glutathione reductase				Bioorg Med Chem Lett 19: 3661-3 (2009) Article DOI: 10.1016/j.bmcl.2009.04.087 BindingDB Entry DOI: 10.7270/Q2930V34
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50015950 (1,3-bis(2-chloroethyl)-1-nitrosourea | Bicnu (TN) ...) Show SMILES ClCCNC(=O)N(CCCl)N=O Show InChI InChI=1S/C5H9Cl2N3O2/c6-1-3-8-5(11)10(9-12)4-2-7/h1-4H2,(H,8,11)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	8.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Minas Gerais Curated by ChEMBL					Assay Description Inhibition of human recombinant glutathione reductase using glutathione as substrate preincubated for 30 mins by colorimetric assay				Eur J Med Chem 71: 282-9 (2014) Article DOI: 10.1016/j.ejmech.2013.11.011 BindingDB Entry DOI: 10.7270/Q25Q4XKQ
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50293665 ((1R(S),2R(S),4R(S),5R(S))-2,5-Dihydroxycyclo-hexan...) Show SMILES OC1CC(O[N+]([O-])=O)C(O)CC1O[N+]([O-])=O Show InChI InChI=1S/C6H10N2O8/c9-3-1-5(15-7(11)12)4(10)2-6(3)16-8(13)14/h3-6,9-10H,1-2H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.71E+3	n/a	n/a	n/a	n/a	n/a	n/a
Atat£rk University Curated by ChEMBL					Assay Description Inhibition of human erythrocyte glutathione reductase				Bioorg Med Chem Lett 19: 3661-3 (2009) Article DOI: 10.1016/j.bmcl.2009.04.087 BindingDB Entry DOI: 10.7270/Q2930V34
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM522150 (US11161815, Example 6) Show SMILES CCCCCCS(=O)(=O)c1nc(Cl)ccc1[N+]([O-])=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.76E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2G73HWC
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM501861 (US11028067, Example 2) Show SMILES [O-][N+](=O)c1ccc(Cl)nc1S(=O)(=O)c1ccccn1 Show InChI InChI=1S/C10H6ClN3O4S/c11-8-5-4-7(14(15)16)10(13-8)19(17,18)9-3-1-2-6-12-9/h1-6H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.89E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oblique Therapeutics AB US Patent					Assay Description Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...				US Patent US11028067 (2021) BindingDB Entry DOI: 10.7270/Q2Q81H65
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50104661 (CHEMBL92155 | Naphthalene-2-sulfonic acid [2-(6-ch...) Show SMILES COc1ccc2nc3cc(Cl)ccc3c(NCCNS(=O)(=O)c3ccc4ccccc4c3)c2c1 Show InChI InChI=1S/C26H22ClN3O3S/c1-33-20-8-11-24-23(16-20)26(22-10-7-19(27)15-25(22)30-24)28-12-13-29-34(31,32)21-9-6-17-4-2-3-5-18(17)14-21/h2-11,14-16,29H,12-13H2,1H3,(H,28,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Inhibitory concentration of the compound against human Glutathione reductase was determined				Bioorg Med Chem Lett 11: 2655-7 (2001) BindingDB Entry DOI: 10.7270/Q2154G90
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50293664 (9(R(S))-Hydroxy-1,2,3,4-tetrahydro-1,4-methano-nap...) Show SMILES OC1C2CC(O[N+]([O-])=O)C1c1ccccc21 |TLB:11:10:1:4.3,14:15:1:4.3,5:4:1:15.10| Show InChI InChI=1S/C11H11NO4/c13-11-8-5-9(16-12(14)15)10(11)7-4-2-1-3-6(7)8/h1-4,8-11,13H,5H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.03E+4	n/a	n/a	n/a	n/a	n/a	n/a
Atat£rk University Curated by ChEMBL					Assay Description Inhibition of human erythrocyte glutathione reductase				Bioorg Med Chem Lett 19: 3661-3 (2009) Article DOI: 10.1016/j.bmcl.2009.04.087 BindingDB Entry DOI: 10.7270/Q2930V34
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50293663 ((1S(R),2S(R),5R(S),6R(S))-5-Bromo-9-oxabicyclo[4.2...) Show SMILES [O-][N+](=O)OC1CCC(Br)C2CCC1O2 Show InChI InChI=1S/C8H12BrNO4/c9-5-1-2-8(14-10(11)12)7-4-3-6(5)13-7/h5-8H,1-4H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Atat£rk University Curated by ChEMBL					Assay Description Inhibition of human erythrocyte glutathione reductase				Bioorg Med Chem Lett 19: 3661-3 (2009) Article DOI: 10.1016/j.bmcl.2009.04.087 BindingDB Entry DOI: 10.7270/Q2930V34
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM501863 (US11028067, Example 4) Show SMILES COc1ccc(c(n1)S(=O)(=O)c1ccncc1)[N+]([O-])=O Show InChI InChI=1S/C11H9N3O5S/c1-19-10-3-2-9(14(15)16)11(13-10)20(17,18)8-4-6-12-7-5-8/h2-7H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.12E+4	n/a	n/a	n/a	n/a	n/a	n/a
Oblique Therapeutics AB US Patent					Assay Description Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...				US Patent US11028067 (2021) BindingDB Entry DOI: 10.7270/Q2Q81H65
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM94597 ((Z)-2-butenedioate;10-(1-methyl-4-piperidinylidene...) Show SMILES [#6]-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6]-1/c2ccsc2-[#6](=O)-[#6]-c2ccccc-12 Show InChI InChI=1S/C19H19NOS/c1-20-9-6-13(7-10-20)18-15-5-3-2-4-14(15)12-17(21)19-16(18)8-11-22-19/h2-5,8,11H,6-7,9-10,12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid UniChem Similars	Article PubMed	800	-8.31	1.20E+4	n/a	n/a	n/a	n/a	8.0	25
Ataturk University					Assay Description GR activity was determined by the method of Carlberg and Mannervik [Carlberg et al., FL:Academic Press, 72:248-254] with a Shimadzu Spectrophotometer...				J Enzyme Inhib Med Chem 27: 18-23 (2012) Article DOI: 10.3109/14756366.2011.572879 BindingDB Entry DOI: 10.7270/Q20K27GD
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Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50052005 (CHEMBL289205 | [10-(4-Chloro-phenyl)-2,4-dioxo-4,1...) Show SMILES OC(=O)Cn1c(=O)nc2n(-c3ccc(Cl)cc3)c3ccccc3nc2c1=O Show InChI InChI=1S/C18H11ClN4O4/c19-10-5-7-11(8-6-10)23-13-4-2-1-3-12(13)20-15-16(23)21-18(27)22(17(15)26)9-14(24)25/h1-8H,9H2,(H,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institut für Biochemie II der Universität Curated by ChEMBL					Assay Description Inhibitory activity against human glutathione reductase in presence of 100 microM GSSG				J Med Chem 39: 1549-54 (1996) Article DOI: 10.1021/jm950511+ BindingDB Entry DOI: 10.7270/Q2F18XTZ
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50054332 (3-Oxo-3,5-dihydro-2H-indeno[1,2-c]pyridazine-4-car...) Show SMILES OC(=O)c1c2Cc3ccccc3-c2n[nH]c1=O Show InChI InChI=1S/C12H8N2O3/c15-11-9(12(16)17)8-5-6-3-1-2-4-7(6)10(8)13-14-11/h1-4H,5H2,(H,14,15)(H,16,17)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.23E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of glutathione reductase				J Med Chem 39: 4396-405 (1996) Article DOI: 10.1021/jm960124f BindingDB Entry DOI: 10.7270/Q2N58N21
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Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50352163 (CHEMBL1824792) Show SMILES CC[C@H](CO)NCc1ccc(cc1)[N+]([O-])=O |r| Show InChI InChI=1S/C11H16N2O3/c1-2-10(8-14)12-7-9-3-5-11(6-4-9)13(15)16/h3-6,10,12,14H,2,7-8H2,1H3/t10-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.33E+4	n/a	n/a	n/a	n/a	n/a	n/a
Batman University Curated by ChEMBL					Assay Description Inhibition of human erythrocyte Glutathione reductase				Bioorg Med Chem Lett 21: 5398-402 (2011) Article DOI: 10.1016/j.bmcl.2011.07.002 BindingDB Entry DOI: 10.7270/Q2V69KKH
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Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50104665 (CHEMBL89368 | Naphthalene-2-sulfonic acid [4-(6-ch...) Show SMILES COc1ccc2nc3cc(Cl)ccc3c(NCCCCNS(=O)(=O)c3ccc4ccccc4c3)c2c1 Show InChI InChI=1S/C28H26ClN3O3S/c1-35-22-10-13-26-25(18-22)28(24-12-9-21(29)17-27(24)32-26)30-14-4-5-15-31-36(33,34)23-11-8-19-6-2-3-7-20(19)16-23/h2-3,6-13,16-18,31H,4-5,14-15H2,1H3,(H,30,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.39E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Inhibitory concentration of the compound against human Glutathione reductase was determined				Bioorg Med Chem Lett 11: 2655-7 (2001) BindingDB Entry DOI: 10.7270/Q2154G90
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50052008 (CHEMBL414176 | [10-(3,5-Dichloro-phenyl)-2,4-dioxo...) Show SMILES OC(=O)Cn1c(=O)nc2n(-c3cc(Cl)cc(Cl)c3)c3ccccc3nc2c1=O Show InChI InChI=1S/C18H10Cl2N4O4/c19-9-5-10(20)7-11(6-9)24-13-4-2-1-3-12(13)21-15-16(24)22-18(28)23(17(15)27)8-14(25)26/h1-7H,8H2,(H,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institut für Biochemie II der Universität Curated by ChEMBL					Assay Description Inhibitory activity against human glutathione reductase in presence of 100 microM GSSG				J Med Chem 39: 1549-54 (1996) Article DOI: 10.1021/jm950511+ BindingDB Entry DOI: 10.7270/Q2F18XTZ
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50293661 (CHEMBL556256 | trans-(1S(R),2S(R))-2-Hydroxycycloo...) Show SMILES O[C@H]1CCCCCC[C@@H]1O[N+]([O-])=O |r| Show InChI InChI=1S/C8H15NO4/c10-7-5-3-1-2-4-6-8(7)13-9(11)12/h7-8,10H,1-6H2/t7-,8-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.42E+4	n/a	n/a	n/a	n/a	n/a	n/a
Atat£rk University Curated by ChEMBL					Assay Description Inhibition of human erythrocyte glutathione reductase				Bioorg Med Chem Lett 19: 3661-3 (2009) Article DOI: 10.1016/j.bmcl.2009.04.087 BindingDB Entry DOI: 10.7270/Q2930V34
					More data for this Ligand-Target Pair

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