Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Genome polyprotein (Hepatitis C virus genotype 1b (isolate Taiwan)) | BDBM29340 (triphenylmethane derivative, 12) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.01E+4 | n/a | n/a | n/a | n/a | 7.0 | 22 |
National Taiwan University | Assay Description The enzyme was assayed the DNA helicase activity by using DNA substrate (annealed BHQ1-labeled release strand and FITC-labeled template strand) in th... | J Med Chem 52: 2716-23 (2009) Article DOI: 10.1021/jm8011905 BindingDB Entry DOI: 10.7270/Q2RF5SBT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus genotype 1b (isolate Taiwan)) | BDBM29331 (triphenylmethane derivative, 3) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.26E+4 | n/a | n/a | n/a | n/a | 7.0 | 22 |
National Taiwan University | Assay Description The enzyme was assayed the DNA helicase activity by using DNA substrate (annealed BHQ1-labeled release strand and FITC-labeled template strand) in th... | J Med Chem 52: 2716-23 (2009) Article DOI: 10.1021/jm8011905 BindingDB Entry DOI: 10.7270/Q2RF5SBT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus genotype 1b (isolate Taiwan)) | BDBM29334 (triphenylmethane derivative, 6) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.39E+4 | n/a | n/a | n/a | n/a | 7.0 | 22 |
National Taiwan University | Assay Description The enzyme was assayed the DNA helicase activity by using DNA substrate (annealed BHQ1-labeled release strand and FITC-labeled template strand) in th... | J Med Chem 52: 2716-23 (2009) Article DOI: 10.1021/jm8011905 BindingDB Entry DOI: 10.7270/Q2RF5SBT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus genotype 1b (isolate Taiwan)) | BDBM29332 (triphenylmethane derivative, 4) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 2.97E+4 | n/a | n/a | n/a | n/a | 7.0 | 22 |
National Taiwan University | Assay Description The enzyme was assayed the DNA helicase activity by using DNA substrate (annealed BHQ1-labeled release strand and FITC-labeled template strand) in th... | J Med Chem 52: 2716-23 (2009) Article DOI: 10.1021/jm8011905 BindingDB Entry DOI: 10.7270/Q2RF5SBT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus genotype 1b (isolate Taiwan)) | BDBM29329 (BHT, 1) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | 4.00E+4 | n/a | n/a | n/a | n/a | 7.0 | 22 |
National Taiwan University | Assay Description The enzyme was assayed the DNA helicase activity by using DNA substrate (annealed BHQ1-labeled release strand and FITC-labeled template strand) in th... | J Med Chem 52: 2716-23 (2009) Article DOI: 10.1021/jm8011905 BindingDB Entry DOI: 10.7270/Q2RF5SBT | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Genome polyprotein (Hepatitis C virus genotype 1b (isolate Taiwan)) | BDBM29338 (diphenol | diphenol derivative, 10) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 6.07E+4 | n/a | n/a | n/a | n/a | 7.0 | 22 |
National Taiwan University | Assay Description The enzyme was assayed the DNA helicase activity by using DNA substrate (annealed BHQ1-labeled release strand and FITC-labeled template strand) in th... | J Med Chem 52: 2716-23 (2009) Article DOI: 10.1021/jm8011905 BindingDB Entry DOI: 10.7270/Q2RF5SBT | |||||||||||
More data for this Ligand-Target Pair |