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Compile Data Set for Download or QSAR

Found 8 hits of ic50 for UniProtKB: Q8TDD5   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mucolipin-3


(Homo sapiens (Human))
BDBM50569847
PNG
(CHEMBL4847300)
Show SMILES COc1ccccc1N1CCN(CC1)[C@H]1CCCC[C@@H]1NS(=O)(=O)c1cccs1 |r|
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.59E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human TRPML3-YFP expressed in HEK293 cells preincubated for 10 mins followed by stimulation with ML-SA1 and measured after 10 mins by F...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
Mucolipin-3


(Homo sapiens (Human))
BDBM50569843
PNG
(CHEMBL4856175)
Show SMILES COc1ccccc1N1CCN(CC1)[C@H]1CCCC[C@@H]1NS(=O)(=O)c1ccccc1 |r|
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

MCE
PC cid
PC sid
PDB
UniChem
Article
PubMed
n/an/a 1.70E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human TRPML3-YFP expressed in HEK293 cells stimulated with ML-SA1 for 200 secs followed by incubation for 200 secs with compound and me...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
Mucolipin-3


(Homo sapiens (Human))
BDBM50569856
PNG
(CHEMBL4875551)
Show SMILES COc1ccccc1N1CCN(CC1)c1ccccc1NS(=O)(=O)c1ccccc1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.17E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human TRPML3-YFP expressed in HEK293 cells preincubated for 10 mins followed by stimulation with ML-SA1 and measured after 10 mins by F...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
Mucolipin-3


(Homo sapiens (Human))
BDBM50569843
PNG
(CHEMBL4856175)
Show SMILES COc1ccccc1N1CCN(CC1)[C@H]1CCCC[C@@H]1NS(=O)(=O)c1ccccc1 |r|
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

MCE
PC cid
PC sid
PDB
UniChem
Article
PubMed
n/an/a 2.85E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human TRPML3-YFP expressed in HEK293 cells preincubated for 10 mins followed by stimulation with ML-SA1 and measured after 10 mins by F...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
Mucolipin-3


(Homo sapiens (Human))
BDBM50569843
PNG
(CHEMBL4856175)
Show SMILES COc1ccccc1N1CCN(CC1)[C@H]1CCCC[C@@H]1NS(=O)(=O)c1ccccc1 |r|
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

MCE
PC cid
PC sid
PDB
UniChem
Article
PubMed
n/an/a 2.85E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human TRPML3-YFP expressed in HEK293 cells preincubated for 10 mins followed by stimulation with ML-SA1 and measured after 10 mins by F...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
Mucolipin-3


(Homo sapiens (Human))
BDBM50569853
PNG
(CHEMBL4855589)
Show SMILES COc1ccccc1C1CCN(CC1)[C@H]1CCCC[C@@H]1NS(=O)(=O)c1ccccc1 |r|
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.62E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human TRPML3-YFP expressed in HEK293 cells preincubated for 10 mins followed by stimulation with ML-SA1 and measured after 10 mins by F...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
Mucolipin-3


(Homo sapiens (Human))
BDBM50569852
PNG
(CHEMBL4856325)
Show SMILES CN1CCN(CC1)[C@H]1CCCC[C@@H]1NS(=O)(=O)c1ccccc1 |r|
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human TRPML3-YFP expressed in HEK293 cells preincubated for 10 mins followed by stimulation with ML-SA1 and measured after 10 mins by F...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
Mucolipin-3


(Homo sapiens (Human))
BDBM50569848
PNG
(CHEMBL4858349)
Show SMILES COc1ccccc1N1CCN(CC1)[C@H]1CCCC[C@@H]1NC(=O)c1ccccc1 |r|
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human TRPML3-YFP expressed in HEK293 cells preincubated for 10 mins followed by stimulation with ML-SA1 and measured after 10 mins by F...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair