Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Gamma-aminobutyric acid receptor subunit alpha-5 (RAT) | BDBM50049736 (8-Ethynyl-5-methyl-6-oxo-5,6-dihydro-4H-2,5,10b-tr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Wisconsin-Milwaukee Curated by ChEMBL | Assay Description Inhibition of [3H]flunitrazepam binding to high affinity GABA-A receptor of rat hippocampal membranes | J Med Chem 39: 1928-34 (1996) Article DOI: 10.1021/jm950887n BindingDB Entry DOI: 10.7270/Q2K35SR6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid receptor subunit alpha-5 (RAT) | BDBM50049736 (8-Ethynyl-5-methyl-6-oxo-5,6-dihydro-4H-2,5,10b-tr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 67 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Wisconsin-Milwaukee Curated by ChEMBL | Assay Description Inhibition of [3H]-flunitrazepam binding to alpha5 GABA-A receptor of rat hippocampal membranes | J Med Chem 39: 1928-34 (1996) Article DOI: 10.1021/jm950887n BindingDB Entry DOI: 10.7270/Q2K35SR6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid receptor subunit alpha-5 (RAT) | BDBM50049736 (8-Ethynyl-5-methyl-6-oxo-5,6-dihydro-4H-2,5,10b-tr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 67.2 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Wisconsin-Milwaukee Curated by ChEMBL | Assay Description Inhibition of [3H]-flunitrazepam binding to alpha5 GABA-A receptor of rat hippocampal membranes | J Med Chem 39: 1928-34 (1996) Article DOI: 10.1021/jm950887n BindingDB Entry DOI: 10.7270/Q2K35SR6 | |||||||||||
More data for this Ligand-Target Pair |