Compile Data Set for Download or QSAR

Found 61 hits of ic50 for UniProtKB: P32322   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Pyrroline-5-carboxylate reductase 1, mitochondrial (Homo sapiens)	BDBM50522088 (CHEMBL4442920) Show SMILES CN(CC#C)Cc1ccc(Br)cc1 Show InChI InChI=1S/C11H12BrN/c1-3-8-13(2)9-10-4-6-11(12)7-5-10/h1,4-7H,8-9H2,2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...				Bioorg Med Chem Lett 29: 2626-2631 (2019) Article DOI: 10.1016/j.bmcl.2019.07.047 BindingDB Entry DOI: 10.7270/Q26D5XD2
					More data for this Ligand-Target Pair
Pyrroline-5-carboxylate reductase 1, mitochondrial (Homo sapiens)	BDBM50522095 (CHEMBL4452615) Show SMILES CN(CC#C)Cc1ccc(Cl)cc1Cl Show InChI InChI=1S/C11H11Cl2N/c1-3-6-14(2)8-9-4-5-10(12)7-11(9)13/h1,4-5,7H,6,8H2,2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...				Bioorg Med Chem Lett 29: 2626-2631 (2019) Article DOI: 10.1016/j.bmcl.2019.07.047 BindingDB Entry DOI: 10.7270/Q26D5XD2
					More data for this Ligand-Target Pair
Pyrroline-5-carboxylate reductase 1, mitochondrial (Homo sapiens)	BDBM50522061 (CHEMBL4462797) Show SMILES CN(CC#C)Cc1ccc(I)cc1 Show InChI InChI=1S/C11H12IN/c1-3-8-13(2)9-10-4-6-11(12)7-5-10/h1,4-7H,8-9H2,2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...				Bioorg Med Chem Lett 29: 2626-2631 (2019) Article DOI: 10.1016/j.bmcl.2019.07.047 BindingDB Entry DOI: 10.7270/Q26D5XD2
					More data for this Ligand-Target Pair
Pyrroline-5-carboxylate reductase 1, mitochondrial (Homo sapiens)	BDBM50522060 (CHEMBL4554584) Show SMILES CN(CC#C)Cc1ccc(Cl)cc1 Show InChI InChI=1S/C11H12ClN/c1-3-8-13(2)9-10-4-6-11(12)7-5-10/h1,4-7H,8-9H2,2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...				Bioorg Med Chem Lett 29: 2626-2631 (2019) Article DOI: 10.1016/j.bmcl.2019.07.047 BindingDB Entry DOI: 10.7270/Q26D5XD2
					More data for this Ligand-Target Pair
Pyrroline-5-carboxylate reductase 1, mitochondrial (Homo sapiens)	BDBM50522110 (CHEMBL4440917) Show SMILES CN(CC#C)Cc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C11H11Cl2N/c1-3-6-14(2)8-9-4-5-10(12)11(13)7-9/h1,4-5,7H,6,8H2,2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.36E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...				Bioorg Med Chem Lett 29: 2626-2631 (2019) Article DOI: 10.1016/j.bmcl.2019.07.047 BindingDB Entry DOI: 10.7270/Q26D5XD2
					More data for this Ligand-Target Pair
Pyrroline-5-carboxylate reductase 1, mitochondrial (Homo sapiens)	BDBM50522058 (CHEMBL4470037) Show SMILES CC#CCN(C)Cc1ccc(Br)cc1 Show InChI InChI=1S/C12H14BrN/c1-3-4-9-14(2)10-11-5-7-12(13)8-6-11/h5-8H,9-10H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...				Bioorg Med Chem Lett 29: 2626-2631 (2019) Article DOI: 10.1016/j.bmcl.2019.07.047 BindingDB Entry DOI: 10.7270/Q26D5XD2
					More data for this Ligand-Target Pair
Pyrroline-5-carboxylate reductase 1, mitochondrial (Homo sapiens)	BDBM50522056 (CHEMBL4442170) Show SMILES CN(CC#C)Cc1ccc2ccccc2c1 Show InChI InChI=1S/C15H15N/c1-3-10-16(2)12-13-8-9-14-6-4-5-7-15(14)11-13/h1,4-9,11H,10,12H2,2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...				Bioorg Med Chem Lett 29: 2626-2631 (2019) Article DOI: 10.1016/j.bmcl.2019.07.047 BindingDB Entry DOI: 10.7270/Q26D5XD2
					More data for this Ligand-Target Pair
Pyrroline-5-carboxylate reductase 1, mitochondrial (Homo sapiens)	BDBM50522097 (CHEMBL4578387) Show SMILES COc1cc(Br)ccc1CN(C)CC#C Show InChI InChI=1S/C12H14BrNO/c1-4-7-14(2)9-10-5-6-11(13)8-12(10)15-3/h1,5-6,8H,7,9H2,2-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...				Bioorg Med Chem Lett 29: 2626-2631 (2019) Article DOI: 10.1016/j.bmcl.2019.07.047 BindingDB Entry DOI: 10.7270/Q26D5XD2
					More data for this Ligand-Target Pair
Pyrroline-5-carboxylate reductase 1, mitochondrial (Homo sapiens)	BDBM50522112 (CHEMBL4538363) Show SMILES CN(CC#C)Cc1ccc(Br)cc1Cl Show InChI InChI=1S/C11H11BrClN/c1-3-6-14(2)8-9-4-5-10(12)7-11(9)13/h1,4-5,7H,6,8H2,2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...				Bioorg Med Chem Lett 29: 2626-2631 (2019) Article DOI: 10.1016/j.bmcl.2019.07.047 BindingDB Entry DOI: 10.7270/Q26D5XD2
					More data for this Ligand-Target Pair
Pyrroline-5-carboxylate reductase 1, mitochondrial (Homo sapiens)	BDBM50522064 (CHEMBL4471360) Show SMILES COc1ccc(CN(C)CC#C)cc1 Show InChI InChI=1S/C12H15NO/c1-4-9-13(2)10-11-5-7-12(14-3)8-6-11/h1,5-8H,9-10H2,2-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...				Bioorg Med Chem Lett 29: 2626-2631 (2019) Article DOI: 10.1016/j.bmcl.2019.07.047 BindingDB Entry DOI: 10.7270/Q26D5XD2
					More data for this Ligand-Target Pair
Pyrroline-5-carboxylate reductase 1, mitochondrial (Homo sapiens)	BDBM50522075 (CHEMBL4449993) Show SMILES CN(CC#C)Cc1ccc(Br)cc1C Show InChI InChI=1S/C12H14BrN/c1-4-7-14(3)9-11-5-6-12(13)8-10(11)2/h1,5-6,8H,7,9H2,2-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...				Bioorg Med Chem Lett 29: 2626-2631 (2019) Article DOI: 10.1016/j.bmcl.2019.07.047 BindingDB Entry DOI: 10.7270/Q26D5XD2
					More data for this Ligand-Target Pair
Pyrroline-5-carboxylate reductase 1, mitochondrial (Homo sapiens)	BDBM50522109 (CHEMBL4441578) Show SMILES CN(CC#C)Cc1ccc(C)cc1 Show InChI InChI=1S/C12H15N/c1-4-9-13(3)10-12-7-5-11(2)6-8-12/h1,5-8H,9-10H2,2-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...				Bioorg Med Chem Lett 29: 2626-2631 (2019) Article DOI: 10.1016/j.bmcl.2019.07.047 BindingDB Entry DOI: 10.7270/Q26D5XD2
					More data for this Ligand-Target Pair
Pyrroline-5-carboxylate reductase 1, mitochondrial (Homo sapiens)	BDBM50522096 (CHEMBL4441742) Show SMILES CN(CC#C)Cc1ccc(Br)cc1F Show InChI InChI=1S/C11H11BrFN/c1-3-6-14(2)8-9-4-5-10(12)7-11(9)13/h1,4-5,7H,6,8H2,2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...				Bioorg Med Chem Lett 29: 2626-2631 (2019) Article DOI: 10.1016/j.bmcl.2019.07.047 BindingDB Entry DOI: 10.7270/Q26D5XD2
					More data for this Ligand-Target Pair
Pyrroline-5-carboxylate reductase 1, mitochondrial (Homo sapiens)	BDBM50522093 (CHEMBL4566601) Show SMILES CN(CC#C)Cc1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C11H12N2O2/c1-3-8-12(2)9-10-4-6-11(7-5-10)13(14)15/h1,4-7H,8-9H2,2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...				Bioorg Med Chem Lett 29: 2626-2631 (2019) Article DOI: 10.1016/j.bmcl.2019.07.047 BindingDB Entry DOI: 10.7270/Q26D5XD2
					More data for this Ligand-Target Pair
Pyrroline-5-carboxylate reductase 1, mitochondrial (Homo sapiens)	BDBM50522070 (CHEMBL4545182) Show SMILES CN(CC#C)Cc1ccc(Cl)c(c1)C(F)(F)F Show InChI InChI=1S/C12H11ClF3N/c1-3-6-17(2)8-9-4-5-11(13)10(7-9)12(14,15)16/h1,4-5,7H,6,8H2,2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...				Bioorg Med Chem Lett 29: 2626-2631 (2019) Article DOI: 10.1016/j.bmcl.2019.07.047 BindingDB Entry DOI: 10.7270/Q26D5XD2
					More data for this Ligand-Target Pair
Pyrroline-5-carboxylate reductase 1, mitochondrial (Homo sapiens)	BDBM50522062 (CHEMBL4518799) Show SMILES CN(CC#C)Cc1cccc(Cl)c1 Show InChI InChI=1S/C11H12ClN/c1-3-7-13(2)9-10-5-4-6-11(12)8-10/h1,4-6,8H,7,9H2,2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...				Bioorg Med Chem Lett 29: 2626-2631 (2019) Article DOI: 10.1016/j.bmcl.2019.07.047 BindingDB Entry DOI: 10.7270/Q26D5XD2
					More data for this Ligand-Target Pair
Pyrroline-5-carboxylate reductase 1, mitochondrial (Homo sapiens)	BDBM50522072 (CHEMBL4521734) Show SMILES CN(CC#C)Cc1ccc(C)cc1C Show InChI InChI=1S/C13H17N/c1-5-8-14(4)10-13-7-6-11(2)9-12(13)3/h1,6-7,9H,8,10H2,2-4H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...				Bioorg Med Chem Lett 29: 2626-2631 (2019) Article DOI: 10.1016/j.bmcl.2019.07.047 BindingDB Entry DOI: 10.7270/Q26D5XD2
					More data for this Ligand-Target Pair
Pyrroline-5-carboxylate reductase 1, mitochondrial (Homo sapiens)	BDBM50522078 (CHEMBL4524807) Show SMILES CCN(CC#C)Cc1ccc(Br)cc1 Show InChI InChI=1S/C12H14BrN/c1-3-9-14(4-2)10-11-5-7-12(13)8-6-11/h1,5-8H,4,9-10H2,2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...				Bioorg Med Chem Lett 29: 2626-2631 (2019) Article DOI: 10.1016/j.bmcl.2019.07.047 BindingDB Entry DOI: 10.7270/Q26D5XD2
					More data for this Ligand-Target Pair
Pyrroline-5-carboxylate reductase 1, mitochondrial (Homo sapiens)	BDBM50522054 (CHEMBL4471016) Show SMILES CN(CC#C)Cc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C12H12F3N/c1-3-8-16(2)9-10-4-6-11(7-5-10)12(13,14)15/h1,4-7H,8-9H2,2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...				Bioorg Med Chem Lett 29: 2626-2631 (2019) Article DOI: 10.1016/j.bmcl.2019.07.047 BindingDB Entry DOI: 10.7270/Q26D5XD2
					More data for this Ligand-Target Pair
Pyrroline-5-carboxylate reductase 1, mitochondrial (Homo sapiens)	BDBM50522101 (CHEMBL4589637) Show SMILES CN(CC#C)Cc1ccc(Cl)cc1Br Show InChI InChI=1S/C11H11BrClN/c1-3-6-14(2)8-9-4-5-10(13)7-11(9)12/h1,4-5,7H,6,8H2,2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...				Bioorg Med Chem Lett 29: 2626-2631 (2019) Article DOI: 10.1016/j.bmcl.2019.07.047 BindingDB Entry DOI: 10.7270/Q26D5XD2
					More data for this Ligand-Target Pair
Pyrroline-5-carboxylate reductase 1, mitochondrial (Homo sapiens)	BDBM50522087 (CHEMBL4531369) Show SMILES CN(CC#Cc1ccccc1)Cc1ccc(Br)cc1 Show InChI InChI=1S/C17H16BrN/c1-19(14-16-9-11-17(18)12-10-16)13-5-8-15-6-3-2-4-7-15/h2-4,6-7,9-12H,13-14H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...				Bioorg Med Chem Lett 29: 2626-2631 (2019) Article DOI: 10.1016/j.bmcl.2019.07.047 BindingDB Entry DOI: 10.7270/Q26D5XD2
					More data for this Ligand-Target Pair
Pyrroline-5-carboxylate reductase 1, mitochondrial (Homo sapiens)	BDBM50522057 (CHEMBL4450640) Show SMILES Brc1ccc(CN(CC#C)Cc2ccc(Br)cc2)cc1 Show InChI InChI=1S/C17H15Br2N/c1-2-11-20(12-14-3-7-16(18)8-4-14)13-15-5-9-17(19)10-6-15/h1,3-10H,11-13H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...				Bioorg Med Chem Lett 29: 2626-2631 (2019) Article DOI: 10.1016/j.bmcl.2019.07.047 BindingDB Entry DOI: 10.7270/Q26D5XD2
					More data for this Ligand-Target Pair
Pyrroline-5-carboxylate reductase 1, mitochondrial (Homo sapiens)	BDBM50522077 (CHEMBL4540573) Show SMILES Brc1ccc(CNCC#C)cc1 Show InChI InChI=1S/C10H10BrN/c1-2-7-12-8-9-3-5-10(11)6-4-9/h1,3-6,12H,7-8H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...				Bioorg Med Chem Lett 29: 2626-2631 (2019) Article DOI: 10.1016/j.bmcl.2019.07.047 BindingDB Entry DOI: 10.7270/Q26D5XD2
					More data for this Ligand-Target Pair
Pyrroline-5-carboxylate reductase 1, mitochondrial (Homo sapiens)	BDBM50522090 (CHEMBL4582299) Show SMILES Cc1cc(CN(CC#C)Cc2ccc(Br)cc2)on1 Show InChI InChI=1S/C15H15BrN2O/c1-3-8-18(11-15-9-12(2)17-19-15)10-13-4-6-14(16)7-5-13/h1,4-7,9H,8,10-11H2,2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...				Bioorg Med Chem Lett 29: 2626-2631 (2019) Article DOI: 10.1016/j.bmcl.2019.07.047 BindingDB Entry DOI: 10.7270/Q26D5XD2
					More data for this Ligand-Target Pair
Pyrroline-5-carboxylate reductase 1, mitochondrial (Homo sapiens)	BDBM50522063 (CHEMBL4572130) Show SMILES CN(CC#C)Cc1ccccc1Cl Show InChI InChI=1S/C11H12ClN/c1-3-8-13(2)9-10-6-4-5-7-11(10)12/h1,4-7H,8-9H2,2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.39E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...				Bioorg Med Chem Lett 29: 2626-2631 (2019) Article DOI: 10.1016/j.bmcl.2019.07.047 BindingDB Entry DOI: 10.7270/Q26D5XD2
					More data for this Ligand-Target Pair
Pyrroline-5-carboxylate reductase 1, mitochondrial (Homo sapiens)	BDBM50522065 (CHEMBL4460666) Show SMILES CC(C)c1ccc(CN(C)CC#C)cc1 Show InChI InChI=1S/C14H19N/c1-5-10-15(4)11-13-6-8-14(9-7-13)12(2)3/h1,6-9,12H,10-11H2,2-4H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.42E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...				Bioorg Med Chem Lett 29: 2626-2631 (2019) Article DOI: 10.1016/j.bmcl.2019.07.047 BindingDB Entry DOI: 10.7270/Q26D5XD2
					More data for this Ligand-Target Pair
Pyrroline-5-carboxylate reductase 1, mitochondrial (Homo sapiens)	BDBM50522091 (CHEMBL4551995) Show SMILES CN(CC=C)Cc1ccc(Br)cc1 Show InChI InChI=1S/C11H14BrN/c1-3-8-13(2)9-10-4-6-11(12)7-5-10/h3-7H,1,8-9H2,2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.61E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...				Bioorg Med Chem Lett 29: 2626-2631 (2019) Article DOI: 10.1016/j.bmcl.2019.07.047 BindingDB Entry DOI: 10.7270/Q26D5XD2
					More data for this Ligand-Target Pair
Pyrroline-5-carboxylate reductase 1, mitochondrial (Homo sapiens)	BDBM50522068 (CHEMBL4441214) Show SMILES CN(CC#C)Cc1ccc(cc1)C(C)=O Show InChI InChI=1S/C13H15NO/c1-4-9-14(3)10-12-5-7-13(8-6-12)11(2)15/h1,5-8H,9-10H2,2-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.84E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...				Bioorg Med Chem Lett 29: 2626-2631 (2019) Article DOI: 10.1016/j.bmcl.2019.07.047 BindingDB Entry DOI: 10.7270/Q26D5XD2
					More data for this Ligand-Target Pair
Pyrroline-5-carboxylate reductase 1, mitochondrial (Homo sapiens)	BDBM50172756 (Benzyl-methyl-prop-2-ynyl-amine | CHEMBL673 | Euto...) Show SMILES CN(CC#C)Cc1ccccc1 Show InChI InChI=1S/C11H13N/c1-3-9-12(2)10-11-7-5-4-6-8-11/h1,4-8H,9-10H2,2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.98E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...				Bioorg Med Chem Lett 29: 2626-2631 (2019) Article DOI: 10.1016/j.bmcl.2019.07.047 BindingDB Entry DOI: 10.7270/Q26D5XD2
					More data for this Ligand-Target Pair
Pyrroline-5-carboxylate reductase 1, mitochondrial (Homo sapiens)	BDBM50522104 (CHEMBL4582778) Show SMILES CN(CC#C)Cc1ccccc1Br Show InChI InChI=1S/C11H12BrN/c1-3-8-13(2)9-10-6-4-5-7-11(10)12/h1,4-7H,8-9H2,2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...				Bioorg Med Chem Lett 29: 2626-2631 (2019) Article DOI: 10.1016/j.bmcl.2019.07.047 BindingDB Entry DOI: 10.7270/Q26D5XD2
					More data for this Ligand-Target Pair
Pyrroline-5-carboxylate reductase 1, mitochondrial (Homo sapiens)	BDBM50522069 (CHEMBL4560325) Show SMILES CN(CC#C)Cc1ccc(cc1)-c1ccc(F)cc1 Show InChI InChI=1S/C17H16FN/c1-3-12-19(2)13-14-4-6-15(7-5-14)16-8-10-17(18)11-9-16/h1,4-11H,12-13H2,2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.11E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...				Bioorg Med Chem Lett 29: 2626-2631 (2019) Article DOI: 10.1016/j.bmcl.2019.07.047 BindingDB Entry DOI: 10.7270/Q26D5XD2
					More data for this Ligand-Target Pair
Pyrroline-5-carboxylate reductase 1, mitochondrial (Homo sapiens)	BDBM50522074 (CHEMBL4451218) Show SMILES CN(CC#C)Cc1ccc(Br)cc1Br Show InChI InChI=1S/C11H11Br2N/c1-3-6-14(2)8-9-4-5-10(12)7-11(9)13/h1,4-5,7H,6,8H2,2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.28E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...				Bioorg Med Chem Lett 29: 2626-2631 (2019) Article DOI: 10.1016/j.bmcl.2019.07.047 BindingDB Entry DOI: 10.7270/Q26D5XD2
					More data for this Ligand-Target Pair
Pyrroline-5-carboxylate reductase 1, mitochondrial (Homo sapiens)	BDBM50522092 (CHEMBL4529176) Show SMILES CN(CC#C)Cc1cccc(Br)c1 Show InChI InChI=1S/C11H12BrN/c1-3-7-13(2)9-10-5-4-6-11(12)8-10/h1,4-6,8H,7,9H2,2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.76E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...				Bioorg Med Chem Lett 29: 2626-2631 (2019) Article DOI: 10.1016/j.bmcl.2019.07.047 BindingDB Entry DOI: 10.7270/Q26D5XD2
					More data for this Ligand-Target Pair
Pyrroline-5-carboxylate reductase 1, mitochondrial (Homo sapiens)	BDBM50522059 (CHEMBL4529927) Show SMILES CN(CC#C)Cc1ccc(F)cc1 Show InChI InChI=1S/C11H12FN/c1-3-8-13(2)9-10-4-6-11(12)7-5-10/h1,4-7H,8-9H2,2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.11E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...				Bioorg Med Chem Lett 29: 2626-2631 (2019) Article DOI: 10.1016/j.bmcl.2019.07.047 BindingDB Entry DOI: 10.7270/Q26D5XD2
					More data for this Ligand-Target Pair
Pyrroline-5-carboxylate reductase 1, mitochondrial (Homo sapiens)	BDBM50522094 (CHEMBL4525457) Show SMILES CN(CC#C)Cc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C17H17N/c1-3-13-18(2)14-15-9-11-17(12-10-15)16-7-5-4-6-8-16/h1,4-12H,13-14H2,2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.15E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...				Bioorg Med Chem Lett 29: 2626-2631 (2019) Article DOI: 10.1016/j.bmcl.2019.07.047 BindingDB Entry DOI: 10.7270/Q26D5XD2
					More data for this Ligand-Target Pair
Pyrroline-5-carboxylate reductase 1, mitochondrial (Homo sapiens)	BDBM50522111 (CHEMBL4562371) Show SMILES CC(N(C)CC#C)c1ccc(Br)cc1 Show InChI InChI=1S/C12H14BrN/c1-4-9-14(3)10(2)11-5-7-12(13)8-6-11/h1,5-8,10H,9H2,2-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.16E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...				Bioorg Med Chem Lett 29: 2626-2631 (2019) Article DOI: 10.1016/j.bmcl.2019.07.047 BindingDB Entry DOI: 10.7270/Q26D5XD2
					More data for this Ligand-Target Pair
Pyrroline-5-carboxylate reductase 1, mitochondrial (Homo sapiens)	BDBM50522085 (CHEMBL4465015) Show SMILES CN(CCC#C)Cc1ccc(Br)cc1 Show InChI InChI=1S/C12H14BrN/c1-3-4-9-14(2)10-11-5-7-12(13)8-6-11/h1,5-8H,4,9-10H2,2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.37E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...				Bioorg Med Chem Lett 29: 2626-2631 (2019) Article DOI: 10.1016/j.bmcl.2019.07.047 BindingDB Entry DOI: 10.7270/Q26D5XD2
					More data for this Ligand-Target Pair
Pyrroline-5-carboxylate reductase 1, mitochondrial (Homo sapiens)	BDBM50522113 (CHEMBL4544449) Show SMILES CC(C#C)N(C)Cc1ccc(Br)cc1 Show InChI InChI=1S/C12H14BrN/c1-4-10(2)14(3)9-11-5-7-12(13)8-6-11/h1,5-8,10H,9H2,2-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.94E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...				Bioorg Med Chem Lett 29: 2626-2631 (2019) Article DOI: 10.1016/j.bmcl.2019.07.047 BindingDB Entry DOI: 10.7270/Q26D5XD2
					More data for this Ligand-Target Pair
Pyrroline-5-carboxylate reductase 1, mitochondrial (Homo sapiens)	BDBM50522066 (CHEMBL4471459) Show SMILES CN(CC#C)Cc1cccc(c1)[N+]([O-])=O Show InChI InChI=1S/C11H12N2O2/c1-3-7-12(2)9-10-5-4-6-11(8-10)13(14)15/h1,4-6,8H,7,9H2,2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.94E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...				Bioorg Med Chem Lett 29: 2626-2631 (2019) Article DOI: 10.1016/j.bmcl.2019.07.047 BindingDB Entry DOI: 10.7270/Q26D5XD2
					More data for this Ligand-Target Pair
Pyrroline-5-carboxylate reductase 1, mitochondrial (Homo sapiens)	BDBM50522080 (CHEMBL4440634) Show SMILES CC(C)N(CC#C)Cc1ccc(Br)cc1 Show InChI InChI=1S/C13H16BrN/c1-4-9-15(11(2)3)10-12-5-7-13(14)8-6-12/h1,5-8,11H,9-10H2,2-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...				Bioorg Med Chem Lett 29: 2626-2631 (2019) Article DOI: 10.1016/j.bmcl.2019.07.047 BindingDB Entry DOI: 10.7270/Q26D5XD2
					More data for this Ligand-Target Pair
Pyrroline-5-carboxylate reductase 1, mitochondrial (Homo sapiens)	BDBM50522079 (CHEMBL4557576) Show SMILES Brc1ccc(CN(CCC=C)CC#C)cc1 Show InChI InChI=1S/C14H16BrN/c1-3-5-11-16(10-4-2)12-13-6-8-14(15)9-7-13/h2-3,6-9H,1,5,10-12H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...				Bioorg Med Chem Lett 29: 2626-2631 (2019) Article DOI: 10.1016/j.bmcl.2019.07.047 BindingDB Entry DOI: 10.7270/Q26D5XD2
					More data for this Ligand-Target Pair
Pyrroline-5-carboxylate reductase 1, mitochondrial (Homo sapiens)	BDBM50522098 (CHEMBL4529870) Show SMILES CCCN(CC#C)Cc1ccc(Br)cc1 Show InChI InChI=1S/C13H16BrN/c1-3-9-15(10-4-2)11-12-5-7-13(14)8-6-12/h1,5-8H,4,9-11H2,2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...				Bioorg Med Chem Lett 29: 2626-2631 (2019) Article DOI: 10.1016/j.bmcl.2019.07.047 BindingDB Entry DOI: 10.7270/Q26D5XD2
					More data for this Ligand-Target Pair
Pyrroline-5-carboxylate reductase 1, mitochondrial (Homo sapiens)	BDBM50522099 (CHEMBL4567902) Show SMILES Brc1ccc2CN(CC#C)Cc2c1 Show InChI InChI=1S/C11H10BrN/c1-2-5-13-7-9-3-4-11(12)6-10(9)8-13/h1,3-4,6H,5,7-8H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...				Bioorg Med Chem Lett 29: 2626-2631 (2019) Article DOI: 10.1016/j.bmcl.2019.07.047 BindingDB Entry DOI: 10.7270/Q26D5XD2
					More data for this Ligand-Target Pair
Pyrroline-5-carboxylate reductase 1, mitochondrial (Homo sapiens)	BDBM50522100 (CHEMBL4475507) Show SMILES CCCN(C)Cc1ccc(Br)cc1 Show InChI InChI=1S/C11H16BrN/c1-3-8-13(2)9-10-4-6-11(12)7-5-10/h4-7H,3,8-9H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...				Bioorg Med Chem Lett 29: 2626-2631 (2019) Article DOI: 10.1016/j.bmcl.2019.07.047 BindingDB Entry DOI: 10.7270/Q26D5XD2
					More data for this Ligand-Target Pair
Pyrroline-5-carboxylate reductase 1, mitochondrial (Homo sapiens)	BDBM50522067 (CHEMBL4545345) Show SMILES CN(CC#C)Cc1ccccc1[N+]([O-])=O Show InChI InChI=1S/C11H12N2O2/c1-3-8-12(2)9-10-6-4-5-7-11(10)13(14)15/h1,4-7H,8-9H2,2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...				Bioorg Med Chem Lett 29: 2626-2631 (2019) Article DOI: 10.1016/j.bmcl.2019.07.047 BindingDB Entry DOI: 10.7270/Q26D5XD2
					More data for this Ligand-Target Pair
Pyrroline-5-carboxylate reductase 1, mitochondrial (Homo sapiens)	BDBM50522102 (CHEMBL4569297) Show SMILES COc1ccc(CN(C)CC#C)c(OC)c1 Show InChI InChI=1S/C13H17NO2/c1-5-8-14(2)10-11-6-7-12(15-3)9-13(11)16-4/h1,6-7,9H,8,10H2,2-4H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...				Bioorg Med Chem Lett 29: 2626-2631 (2019) Article DOI: 10.1016/j.bmcl.2019.07.047 BindingDB Entry DOI: 10.7270/Q26D5XD2
					More data for this Ligand-Target Pair
Pyrroline-5-carboxylate reductase 1, mitochondrial (Homo sapiens)	BDBM50522103 (CHEMBL4529610) Show SMILES CN(Cc1ccccc1)Cc1ccc(Br)cc1 Show InChI InChI=1S/C15H16BrN/c1-17(11-13-5-3-2-4-6-13)12-14-7-9-15(16)10-8-14/h2-10H,11-12H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...				Bioorg Med Chem Lett 29: 2626-2631 (2019) Article DOI: 10.1016/j.bmcl.2019.07.047 BindingDB Entry DOI: 10.7270/Q26D5XD2
					More data for this Ligand-Target Pair
Pyrroline-5-carboxylate reductase 1, mitochondrial (Homo sapiens)	BDBM50522076 (CHEMBL4563322) Show SMILES CN(CCc1ccc(Br)cc1)CC#C Show InChI InChI=1S/C12H14BrN/c1-3-9-14(2)10-8-11-4-6-12(13)7-5-11/h1,4-7H,8-10H2,2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...				Bioorg Med Chem Lett 29: 2626-2631 (2019) Article DOI: 10.1016/j.bmcl.2019.07.047 BindingDB Entry DOI: 10.7270/Q26D5XD2
					More data for this Ligand-Target Pair
Pyrroline-5-carboxylate reductase 1, mitochondrial (Homo sapiens)	BDBM50522105 (CHEMBL4539315) Show SMILES CN(CC#C)Cc1ccc(cc1)C#N Show InChI InChI=1S/C12H12N2/c1-3-8-14(2)10-12-6-4-11(9-13)5-7-12/h1,4-7H,8,10H2,2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...				Bioorg Med Chem Lett 29: 2626-2631 (2019) Article DOI: 10.1016/j.bmcl.2019.07.047 BindingDB Entry DOI: 10.7270/Q26D5XD2
					More data for this Ligand-Target Pair
Pyrroline-5-carboxylate reductase 1, mitochondrial (Homo sapiens)	BDBM50522106 (CHEMBL4560460) Show SMILES CN(CC#C)Cc1cc(C)no1 Show InChI InChI=1S/C9H12N2O/c1-4-5-11(3)7-9-6-8(2)10-12-9/h1,6H,5,7H2,2-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...				Bioorg Med Chem Lett 29: 2626-2631 (2019) Article DOI: 10.1016/j.bmcl.2019.07.047 BindingDB Entry DOI: 10.7270/Q26D5XD2
					More data for this Ligand-Target Pair

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