Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium channel subunit beta-1 (Homo sapiens) | BDBM50530536![]() (CHEMBL4580996 | US11174268, Example 336) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Xenon Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Inhibition of recombinant human full length Nav1.2 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b... | J Med Chem 62: 9618-9641 (2019) Article DOI: 10.1021/acs.jmedchem.9b01032 BindingDB Entry DOI: 10.7270/Q2Z32344 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel subunit beta-1 (Homo sapiens) | BDBM50530536![]() (CHEMBL4580996 | US11174268, Example 336) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Xenon Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Inhibition of recombinant human full length Nav1.2 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b... | J Med Chem 62: 9618-9641 (2019) Article DOI: 10.1021/acs.jmedchem.9b01032 BindingDB Entry DOI: 10.7270/Q2Z32344 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel subunit beta-1 (Homo sapiens) | BDBM50530539![]() (CHEMBL4460028 | US11174268, Example 300) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | n/a |
Xenon Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Inhibition of recombinant human full length Nav1.2 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b... | J Med Chem 62: 9618-9641 (2019) Article DOI: 10.1021/acs.jmedchem.9b01032 BindingDB Entry DOI: 10.7270/Q2Z32344 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel subunit beta-1 (Homo sapiens) | BDBM50530539![]() (CHEMBL4460028 | US11174268, Example 300) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | n/a |
Xenon Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Inhibition of recombinant human full length Nav1.2 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b... | J Med Chem 62: 9618-9641 (2019) Article DOI: 10.1021/acs.jmedchem.9b01032 BindingDB Entry DOI: 10.7270/Q2Z32344 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel subunit beta-1 (Homo sapiens) | BDBM50530535![]() (CHEMBL4466858 | US11174268, Example 205) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 47 | n/a | n/a | n/a | n/a | n/a | n/a |
Xenon Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Inhibition of recombinant human full length Nav1.2 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b... | J Med Chem 62: 9618-9641 (2019) Article DOI: 10.1021/acs.jmedchem.9b01032 BindingDB Entry DOI: 10.7270/Q2Z32344 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel subunit beta-1 (Homo sapiens) | BDBM50530535![]() (CHEMBL4466858 | US11174268, Example 205) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 47 | n/a | n/a | n/a | n/a | n/a | n/a |
Xenon Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Inhibition of recombinant human full length Nav1.2 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b... | J Med Chem 62: 9618-9641 (2019) Article DOI: 10.1021/acs.jmedchem.9b01032 BindingDB Entry DOI: 10.7270/Q2Z32344 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel subunit beta-1 (Homo sapiens) | BDBM50530533![]() (CHEMBL4435054 | US11174268, Example 185) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 66 | n/a | n/a | n/a | n/a | n/a | n/a |
Xenon Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Inhibition of recombinant human full length Nav1.2 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b... | J Med Chem 62: 9618-9641 (2019) Article DOI: 10.1021/acs.jmedchem.9b01032 BindingDB Entry DOI: 10.7270/Q2Z32344 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel subunit beta-1 (Homo sapiens) | BDBM50530533![]() (CHEMBL4435054 | US11174268, Example 185) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 66 | n/a | n/a | n/a | n/a | n/a | n/a |
Xenon Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Inhibition of recombinant human full length Nav1.2 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b... | J Med Chem 62: 9618-9641 (2019) Article DOI: 10.1021/acs.jmedchem.9b01032 BindingDB Entry DOI: 10.7270/Q2Z32344 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel subunit beta-1 (Homo sapiens) | BDBM50530537![]() (CHEMBL4471825) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 125 | n/a | n/a | n/a | n/a | n/a | n/a |
Xenon Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Inhibition of recombinant human full length Nav1.2 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b... | J Med Chem 62: 9618-9641 (2019) Article DOI: 10.1021/acs.jmedchem.9b01032 BindingDB Entry DOI: 10.7270/Q2Z32344 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel subunit beta-1 (Homo sapiens) | BDBM50530537![]() (CHEMBL4471825) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 125 | n/a | n/a | n/a | n/a | n/a | n/a |
Xenon Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Inhibition of recombinant human full length Nav1.2 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b... | J Med Chem 62: 9618-9641 (2019) Article DOI: 10.1021/acs.jmedchem.9b01032 BindingDB Entry DOI: 10.7270/Q2Z32344 | |||||||||||
More data for this Ligand-Target Pair |