Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Potassium voltage-gated channel subfamily A member 3 (Mus musculus) | BDBM50115772 (CHEMBL3609094) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 0.0230 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc. Curated by ChEMBL | Assay Description Displacement of [125I]-ChTX from mouse Kv1.3 after 20 mins by scintillation counting analysis | J Med Chem 58: 6784-802 (2015) Article DOI: 10.1021/acs.jmedchem.5b00495 BindingDB Entry DOI: 10.7270/Q22V2HWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily A member 3 (Mus musculus) | BDBM50083523 ((1-Benzyl-1H-quinolin-4-ylidene)-pentyl-amine | CH...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kiel Curated by ChEMBL | Assay Description Blockade of peak steady-state K+ currents of voltage-gated potassium channel subunit Kv1.3 in mouse fibroblasts L929 at 50 uM | J Med Chem 44: 1249-56 (2001) BindingDB Entry DOI: 10.7270/Q2TH8KZV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily A member 3 (Mus musculus) | BDBM50098785 (4-Benzhydryloxymethyl-1-[3-(4-methoxy-phenyl)-prop...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 280 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kiel Curated by ChEMBL | Assay Description Blockade of peak steady-state K+ currents of voltage-gated potassium channel subunit Kv1.3 in mouse fibroblasts L929 at 50 uM | J Med Chem 44: 1249-56 (2001) BindingDB Entry DOI: 10.7270/Q2TH8KZV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily A member 3 (Mus musculus) | BDBM50098782 (2-Isopropyl-8-methoxy-5-methyl-5H-furo[3,2-c]quino...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kiel Curated by ChEMBL | Assay Description Blockade of peak steady-state K+ currents of voltage-gated potassium channel subunit Kv1.3 in mouse fibroblasts L929 at 50 uM | J Med Chem 44: 1249-56 (2001) BindingDB Entry DOI: 10.7270/Q2TH8KZV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily A member 3 (Mus musculus) | BDBM50098781 (9-Methoxy-2,2,6-trimethyl-2,6-dihydro-pyrano[3,2-c...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kiel Curated by ChEMBL | Assay Description Blockade of peak steady-state K+ currents of voltage-gated potassium channel subunit Kv1.3 in mouse fibroblasts L929 at 50 uM | J Med Chem 44: 1249-56 (2001) BindingDB Entry DOI: 10.7270/Q2TH8KZV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily A member 3 (Mus musculus) | BDBM50098784 (9-Methoxy-2,2,6-trimethyl-2,3,4,6-tetrahydro-pyran...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kiel Curated by ChEMBL | Assay Description Inhibition of voltage-gated potassium channel subunit Kv1.3 expressed in L929 cells | J Med Chem 44: 1249-56 (2001) BindingDB Entry DOI: 10.7270/Q2TH8KZV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily A member 3 (Mus musculus) | BDBM50098783 (4,6,7-Trimethoxy-furo[2,3-b]quinoline | CHEMBL2787...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kiel Curated by ChEMBL | Assay Description Blockade of peak steady-state K+ currents of voltage-gated potassium channel subunit Kv1.3 in mouse fibroblasts L929 at 50 uM | J Med Chem 44: 1249-56 (2001) BindingDB Entry DOI: 10.7270/Q2TH8KZV | |||||||||||
More data for this Ligand-Target Pair |