BindingDB PrimarySearch

Found 9 hits of ic50 for UniProtKB: P0C870
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7 (Homo sapiens)	BDBM50571209 (CHEMBL4846929) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of N-terminal His-tagged human JMJD7 (1 to 316 residues) expressed in Escherichia coli BL21 (DE3) using peptide substrate DRG (16 to 30) m...				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128139 BindingDB Entry DOI: 10.7270/Q2CF9TWH
TBA					More data for this Ligand-Target Pair
Bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7 (Homo sapiens)	BDBM50571209 (CHEMBL4846929) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.62E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of N-terminal His-tagged human JMJD7 (1 to 316 residues) expressed in Escherichia coli BL21 (DE3) luciferase based succinate-gloTM JmjC de...				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128139 BindingDB Entry DOI: 10.7270/Q2CF9TWH
TBA					More data for this Ligand-Target Pair
Bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7 (Homo sapiens)	BDBM16111 (2-{[2-fluoro-4-(3-methoxyphenyl)phenyl]carbamoyl}c...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	7.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of N-terminal His-tagged human JMJD7 (1 to 316 residues) expressed in Escherichia coli BL21 (DE3) luciferase based succinate-gloTM JmjC de...				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128139 BindingDB Entry DOI: 10.7270/Q2CF9TWH
TBA					More data for this Ligand-Target Pair
Bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7 (Homo sapiens)	BDBM40249 (5-(1,3-benzothiazol-2-yl)-N-propyl-2-thiophenecarb...) Show SMILES CCCNC(=O)c1ccc(s1)-c1nc2ccccc2s1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of N-terminal His-tagged human JMJD7 (1 to 316 residues) expressed in Escherichia coli BL21 (DE3) luciferase based succinate-gloTM JmjC de...				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128139 BindingDB Entry DOI: 10.7270/Q2CF9TWH
TBA					More data for this Ligand-Target Pair
Bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7 (Homo sapiens)	BDBM50571208 (CHEMBL4862698) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.62E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of N-terminal His-tagged human JMJD7 (1 to 316 residues) expressed in Escherichia coli BL21 (DE3) luciferase based succinate-gloTM JmjC de...				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128139 BindingDB Entry DOI: 10.7270/Q2CF9TWH
TBA					More data for this Ligand-Target Pair
Bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7 (Homo sapiens)	BDBM50339142 (CHEMBL1688558 \| rac-7-(phenyl(pyridin-2-ylamino)me...) Show SMILES Oc1c(ccc2cccnc12)C(Nc1ccccn1)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of N-terminal His-tagged human JMJD7 (1 to 316 residues) expressed in Escherichia coli BL21 (DE3) luciferase based succinate-gloTM JmjC de...				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128139 BindingDB Entry DOI: 10.7270/Q2CF9TWH
TBA					More data for this Ligand-Target Pair
Bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7 (Homo sapiens)	BDBM50571207 (CHEMBL1081780) Show SMILES COc1ccc(CCC(=O)Nc2ccccc2C(O)=O)cc1OC Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.32E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of N-terminal His-tagged human JMJD7 (1 to 316 residues) expressed in Escherichia coli BL21 (DE3) luciferase based succinate-gloTM JmjC de...				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128139 BindingDB Entry DOI: 10.7270/Q2CF9TWH
TBA					More data for this Ligand-Target Pair
Bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7 (Homo sapiens)	BDBM251460 (US9452998, 9) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	5.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of N-terminal His-tagged human JMJD7 (1 to 316 residues) expressed in Escherichia coli BL21 (DE3) luciferase based succinate-gloTM JmjC de...				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128139 BindingDB Entry DOI: 10.7270/Q2CF9TWH
TBA					More data for this Ligand-Target Pair
Bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7 (Homo sapiens)	BDBM50576306 (CHEMBL4849961) Show SMILES Cn1ccc(n1)-c1cc(ccn1)C(=O)OCC(F)(F)F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of JMJD7 (unknown origin) by Succinate-Glo assay				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128109 BindingDB Entry DOI: 10.7270/Q2FT8QVV
TBA					More data for this Ligand-Target Pair