Compile Data Set for Download or QSAR

Found 15 hits of ic50 for UniProtKB: P96471   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Streptokinase (Streptococcus pyogenes)	BDBM50449290 (CHEMBL3125358) Show SMILES CC1(C)Cc2ccc(cc2-c2nc(SCCOCC#C)n(CC=C)c(=O)c12)N=[N+]=[N-] Show InChI InChI=1S/C22H23N5O2S/c1-5-9-27-20(28)18-19(24-21(27)30-12-11-29-10-6-2)17-13-16(25-26-23)8-7-15(17)14-22(18,3)4/h2,5,7-8,13H,1,9-12,14H2,3-4H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Inhibition of Streptococcus pyogenes UMAA2616 streptokinase assessed as plasmin activity in human plasma after 24 hrs by colorimetric analysis				Bioorg Med Chem Lett 24: 1538-44 (2014) Article DOI: 10.1016/j.bmcl.2014.01.079 BindingDB Entry DOI: 10.7270/Q2959K2G
					More data for this Ligand-Target Pair
Streptokinase (Streptococcus pyogenes)	BDBM50449289 (CHEMBL3125355) Show SMILES CC1(CCOc2ccc-3c(CC(C)(C)c4c-3nc(SCCOCC#C)n(CC=C)c4=O)c2)N=N1 |c:35| Show InChI InChI=1S/C26H30N4O3S/c1-6-11-30-23(31)21-22(27-24(30)34-15-14-32-12-7-2)20-9-8-19(16-18(20)17-25(21,3)4)33-13-10-26(5)28-29-26/h2,6,8-9,16H,1,10-15,17H2,3-5H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Inhibition of Streptococcus pyogenes UMAA2616 streptokinase assessed as plasmin activity in human plasma after 24 hrs by colorimetric analysis				Bioorg Med Chem Lett 24: 1538-44 (2014) Article DOI: 10.1016/j.bmcl.2014.01.079 BindingDB Entry DOI: 10.7270/Q2959K2G
					More data for this Ligand-Target Pair
Streptokinase (Streptococcus pyogenes)	BDBM50449288 (CHEMBL3125359) Show SMILES CCSc1nc2-c3cc(OC)ccc3CC(C)(C)c2c(=O)n1CC=C Show InChI InChI=1S/C20H24N2O2S/c1-6-10-22-18(23)16-17(21-19(22)25-7-2)15-11-14(24-5)9-8-13(15)12-20(16,3)4/h6,8-9,11H,1,7,10,12H2,2-5H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Inhibition of Streptococcus pyogenes UMAA2616 streptokinase assessed as plasmin activity in human plasma after 24 hrs by colorimetric analysis				Bioorg Med Chem Lett 24: 1538-44 (2014) Article DOI: 10.1016/j.bmcl.2014.01.079 BindingDB Entry DOI: 10.7270/Q2959K2G
					More data for this Ligand-Target Pair
Streptokinase (Streptococcus pyogenes)	BDBM50431669 (CHEMBL2349512) Show SMILES CCNc1nc2-c3cc(OC)ccc3CC(C)(C)c2c(=O)n1CC=C Show InChI InChI=1S/C20H25N3O2/c1-6-10-23-18(24)16-17(22-19(23)21-7-2)15-11-14(25-5)9-8-13(15)12-20(16,3)4/h6,8-9,11H,1,7,10,12H2,2-5H3,(H,21,22)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Inhibition of Streptococcus pyogenes UMAA2616 streptokinase assessed as cleavage of S-2403 to colored product p-nitroaniline after 2 hrs				Bioorg Med Chem 21: 1880-97 (2013) Article DOI: 10.1016/j.bmc.2013.01.046 BindingDB Entry DOI: 10.7270/Q2862HTW
					More data for this Ligand-Target Pair
Streptokinase (Streptococcus pyogenes)	BDBM50431670 (CHEMBL2349510) Show SMILES CCSc1nc2-c3ccccc3CC(C)(C)c2c(=O)n1CC=C Show InChI InChI=1S/C19H22N2OS/c1-5-11-21-17(22)15-16(20-18(21)23-6-2)14-10-8-7-9-13(14)12-19(15,3)4/h5,7-10H,1,6,11-12H2,2-4H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Inhibition of Streptococcus pyogenes UMAA2616 streptokinase assessed as cleavage of S-2403 to colored product p-nitroaniline after 2 hrs				Bioorg Med Chem 21: 1880-97 (2013) Article DOI: 10.1016/j.bmc.2013.01.046 BindingDB Entry DOI: 10.7270/Q2862HTW
					More data for this Ligand-Target Pair
Streptokinase (Streptococcus pyogenes)	BDBM50431668 (CCG-203592) Show SMILES CCNc1nc2-c3ccc(OC)cc3CC(C)(C)c2c(=O)n1CC=C Show InChI InChI=1S/C20H25N3O2/c1-6-10-23-18(24)16-17(22-19(23)21-7-2)15-9-8-14(25-5)11-13(15)12-20(16,3)4/h6,8-9,11H,1,7,10,12H2,2-5H3,(H,21,22)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Inhibition of Streptococcus pyogenes UMAA2616 streptokinase assessed as cleavage of S-2403 to colored product p-nitroaniline after 2 hrs				Bioorg Med Chem 21: 1880-97 (2013) Article DOI: 10.1016/j.bmc.2013.01.046 BindingDB Entry DOI: 10.7270/Q2862HTW
					More data for this Ligand-Target Pair
Streptokinase (Streptococcus pyogenes)	BDBM50431672 (CHEMBL2349411) Show SMILES COCCSc1nc2-c3ccccc3CC(C)(C)c2c(=O)n1CC=C Show InChI InChI=1S/C20H24N2O2S/c1-5-10-22-18(23)16-17(21-19(22)25-12-11-24-4)15-9-7-6-8-14(15)13-20(16,2)3/h5-9H,1,10-13H2,2-4H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Inhibition of Streptococcus pyogenes UMAA2616 streptokinase assessed as cleavage of S-2403 to colored product p-nitroaniline after 2 hrs				Bioorg Med Chem 21: 1880-97 (2013) Article DOI: 10.1016/j.bmc.2013.01.046 BindingDB Entry DOI: 10.7270/Q2862HTW
					More data for this Ligand-Target Pair
Streptokinase (Streptococcus pyogenes)	BDBM50449287 (CHEMBL3125353) Show SMILES CC1(C)Cc2cc(ccc2-c2nc(SCCOCC#C)n(CC=C)c(=O)c12)C(=O)c1ccccc1 Show InChI InChI=1S/C29H28N2O3S/c1-5-14-31-27(33)24-25(30-28(31)35-17-16-34-15-6-2)23-13-12-21(18-22(23)19-29(24,3)4)26(32)20-10-8-7-9-11-20/h2,5,7-13,18H,1,14-17,19H2,3-4H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Inhibition of Streptococcus pyogenes UMAA2616 streptokinase assessed as plasmin activity in human plasma after 24 hrs by colorimetric analysis				Bioorg Med Chem Lett 24: 1538-44 (2014) Article DOI: 10.1016/j.bmcl.2014.01.079 BindingDB Entry DOI: 10.7270/Q2959K2G
					More data for this Ligand-Target Pair
Streptokinase (Streptococcus pyogenes)	BDBM50431666 (CHEMBL2349398) Show SMILES CCNc1nc2-c3ccc(OC(C)C)cc3CC(C)(C)c2c(=O)n1CC=C Show InChI InChI=1S/C22H29N3O2/c1-7-11-25-20(26)18-19(24-21(25)23-8-2)17-10-9-16(27-14(3)4)12-15(17)13-22(18,5)6/h7,9-10,12,14H,1,8,11,13H2,2-6H3,(H,23,24)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Inhibition of Streptococcus pyogenes UMAA2616 streptokinase assessed as cleavage of S-2403 to colored product p-nitroaniline after 2 hrs				Bioorg Med Chem 21: 1880-97 (2013) Article DOI: 10.1016/j.bmc.2013.01.046 BindingDB Entry DOI: 10.7270/Q2862HTW
					More data for this Ligand-Target Pair
Streptokinase (Streptococcus pyogenes)	BDBM50431665 (CHEMBL2349388) Show SMILES COCCNc1nc(OCCc2ccc(OC)cc2)c2c(n1)-c1ccccc1CC2(C)C Show InChI InChI=1S/C26H31N3O3/c1-26(2)17-19-7-5-6-8-21(19)23-22(26)24(29-25(28-23)27-14-16-30-3)32-15-13-18-9-11-20(31-4)12-10-18/h5-12H,13-17H2,1-4H3,(H,27,28,29)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Inhibition of Streptococcus pyogenes UMAA2616 streptokinase assessed as cleavage of S-2403 to colored product p-nitroaniline after 2 hrs				Bioorg Med Chem 21: 1880-97 (2013) Article DOI: 10.1016/j.bmc.2013.01.046 BindingDB Entry DOI: 10.7270/Q2862HTW
					More data for this Ligand-Target Pair
Streptokinase (Streptococcus pyogenes)	BDBM50431667 (CHEMBL2349392) Show SMILES COc1ccc-2c(CC(C)(C)c3c-2nc(NCC=C)n(CC=C)c3=O)c1 Show InChI InChI=1S/C21H25N3O2/c1-6-10-22-20-23-18-16-9-8-15(26-5)12-14(16)13-21(3,4)17(18)19(25)24(20)11-7-2/h6-9,12H,1-2,10-11,13H2,3-5H3,(H,22,23)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Inhibition of Streptococcus pyogenes UMAA2616 streptokinase assessed as cleavage of S-2403 to colored product p-nitroaniline after 2 hrs				Bioorg Med Chem 21: 1880-97 (2013) Article DOI: 10.1016/j.bmc.2013.01.046 BindingDB Entry DOI: 10.7270/Q2862HTW
					More data for this Ligand-Target Pair
Streptokinase (Streptococcus pyogenes)	BDBM50431671 (CHEMBL2349509) Show SMILES CC1(C)Cc2ccccc2-c2nc(SCc3ccccc3)n(CC=C)c(=O)c12 Show InChI InChI=1S/C24H24N2OS/c1-4-14-26-22(27)20-21(19-13-9-8-12-18(19)15-24(20,2)3)25-23(26)28-16-17-10-6-5-7-11-17/h4-13H,1,14-16H2,2-3H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.08E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Inhibition of Streptococcus pyogenes UMAA2616 streptokinase assessed as cleavage of S-2403 to colored product p-nitroaniline after 2 hrs				Bioorg Med Chem 21: 1880-97 (2013) Article DOI: 10.1016/j.bmc.2013.01.046 BindingDB Entry DOI: 10.7270/Q2862HTW
					More data for this Ligand-Target Pair
Streptokinase (Streptococcus pyogenes)	BDBM50431673 (CHEMBL2349522) Show SMILES CSc1nc2-c3ccccc3CC3(CCCCC3)c2c(=O)n1CC=C Show InChI InChI=1S/C21H24N2OS/c1-3-13-23-19(24)17-18(22-20(23)25-2)16-10-6-5-9-15(16)14-21(17)11-7-4-8-12-21/h3,5-6,9-10H,1,4,7-8,11-14H2,2H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Inhibition of Streptococcus pyogenes UMAA2616 streptokinase assessed as cleavage of S-2403 to colored product p-nitroaniline after 2 hrs				Bioorg Med Chem 21: 1880-97 (2013) Article DOI: 10.1016/j.bmc.2013.01.046 BindingDB Entry DOI: 10.7270/Q2862HTW
					More data for this Ligand-Target Pair
Streptokinase (Streptococcus pyogenes)	BDBM50431674 (CCG-102487) Show SMILES C=CCn1c(SCc2ccccc2)nc2-c3ccccc3CC3(CCCCC3)c2c1=O Show InChI InChI=1S/C27H28N2OS/c1-2-17-29-25(30)23-24(28-26(29)31-19-20-11-5-3-6-12-20)22-14-8-7-13-21(22)18-27(23)15-9-4-10-16-27/h2-3,5-8,11-14H,1,4,9-10,15-19H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Inhibition of Streptococcus pyogenes UMAA2616 streptokinase assessed as cleavage of S-2403 to colored product p-nitroaniline after 2 hrs				Bioorg Med Chem 21: 1880-97 (2013) Article DOI: 10.1016/j.bmc.2013.01.046 BindingDB Entry DOI: 10.7270/Q2862HTW
					More data for this Ligand-Target Pair
Streptokinase (Streptococcus pyogenes)	BDBM50431675 (CCG-2979) Show SMILES CCCCSc1nc2-c3ccccc3CC3(CCCCC3)c2c(=O)n1CC=C Show InChI InChI=1S/C24H30N2OS/c1-3-5-16-28-23-25-21-19-12-8-7-11-18(19)17-24(13-9-6-10-14-24)20(21)22(27)26(23)15-4-2/h4,7-8,11-12H,2-3,5-6,9-10,13-17H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Inhibition of Streptococcus pyogenes UMAA2616 streptokinase assessed as cleavage of S-2403 to colored product p-nitroaniline after 2 hrs				Bioorg Med Chem 21: 1880-97 (2013) Article DOI: 10.1016/j.bmc.2013.01.046 BindingDB Entry DOI: 10.7270/Q2862HTW
					More data for this Ligand-Target Pair