Found 256 hits of ic50 for UniProtKB: P48426 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
(Homo sapiens) | BDBM50611048
(BAY-091)Show SMILES CC[C@@H](Nc1c(C#N)c(nc2cnccc12)-c1ccc(cc1)-c1cccc(C)c1F)C(O)=O | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| PC cid
PC sid
PDB
UniChem
| PDB
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
(Homo sapiens) | BDBM50611049
(CHEMBL5280127)Show SMILES CC[C@@H](Nc1c(C#N)c(nc2cnccc12)-c1ccc(cc1)-c1cccc(Cl)c1F)C(O)=O |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this
Ligand-Target Pair | |
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
(Homo sapiens) | BDBM50611049
(CHEMBL5280127)Show SMILES CC[C@@H](Nc1c(C#N)c(nc2cnccc12)-c1ccc(cc1)-c1cccc(Cl)c1F)C(O)=O |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
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More data for this
Ligand-Target Pair | |
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
(Homo sapiens) | BDBM50611048
(BAY-091)Show SMILES CC[C@@H](Nc1c(C#N)c(nc2cnccc12)-c1ccc(cc1)-c1cccc(C)c1F)C(O)=O | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
PDB
UniChem
| PDB
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
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More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
(Homo sapiens) | BDBM50610997
(CHEMBL5276719)Show SMILES CCOc1ccccc1-c1ccc(cc1)-c1nc2cnccc2c(N[C@H](CC)C(O)=O)c1C#N |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
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More data for this
Ligand-Target Pair | |
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
(Homo sapiens) | BDBM50610997
(CHEMBL5276719)Show SMILES CCOc1ccccc1-c1ccc(cc1)-c1nc2cnccc2c(N[C@H](CC)C(O)=O)c1C#N |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 5.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
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More data for this
Ligand-Target Pair | |
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
(Homo sapiens) | BDBM50611050
(CHEMBL5270765)Show SMILES CCOc1ccccc1-c1ccc(cc1)-c1nc2cncc(Cl)c2c(N[C@H](CC)C(N)=O)c1C#N |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
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More data for this
Ligand-Target Pair | |
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
(Homo sapiens) | BDBM50611048
(BAY-091)Show SMILES CC[C@@H](Nc1c(C#N)c(nc2cnccc12)-c1ccc(cc1)-c1cccc(C)c1F)C(O)=O | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
PDB
UniChem
| PDB
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
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More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
(Homo sapiens) | BDBM50611046
(CHEMBL5290005)Show SMILES CC[C@@H](Nc1c(C#N)c(nc2cnccc12)-c1ccc(cc1)-c1cccc(Cl)c1F)C(N)=O |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
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PDB
UniChem
| PDB
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
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Ligand-Target Pair |
3D Structure (crystal) |
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
(Homo sapiens) | BDBM50610996
(CHEMBL5271652)Show SMILES CCOc1ccccc1-c1ccc(cc1)-c1nc2cnccc2c(NC(C)C(O)=O)c1C#N | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
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More data for this
Ligand-Target Pair | |
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
(Homo sapiens) | BDBM50611049
(CHEMBL5280127)Show SMILES CC[C@@H](Nc1c(C#N)c(nc2cnccc12)-c1ccc(cc1)-c1cccc(Cl)c1F)C(O)=O |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
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More data for this
Ligand-Target Pair | |
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
(Homo sapiens) | BDBM50611048
(BAY-091)Show SMILES CC[C@@H](Nc1c(C#N)c(nc2cnccc12)-c1ccc(cc1)-c1cccc(C)c1F)C(O)=O | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
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PDB
UniChem
| PDB
| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
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Ligand-Target Pair |
3D Structure (crystal) |
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
(Homo sapiens) | BDBM50611047
(CHEMBL5277824)Show SMILES CC[C@@H](Nc1c(C#N)c(nc2cnccc12)-c1ccc(cc1)-c1cccc(C)c1F)C(N)=O |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
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UniChem
| | n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
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More data for this
Ligand-Target Pair | |
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
(Homo sapiens) | BDBM50611050
(CHEMBL5270765)Show SMILES CCOc1ccccc1-c1ccc(cc1)-c1nc2cncc(Cl)c2c(N[C@H](CC)C(N)=O)c1C#N |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
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More data for this
Ligand-Target Pair | |
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
(Homo sapiens) | BDBM50610997
(CHEMBL5276719)Show SMILES CCOc1ccccc1-c1ccc(cc1)-c1nc2cnccc2c(N[C@H](CC)C(O)=O)c1C#N |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this
Ligand-Target Pair | |
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
(Homo sapiens) | BDBM50611049
(CHEMBL5280127)Show SMILES CC[C@@H](Nc1c(C#N)c(nc2cnccc12)-c1ccc(cc1)-c1cccc(Cl)c1F)C(O)=O |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
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More data for this
Ligand-Target Pair | |
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
(Homo sapiens) | BDBM50611013
(CHEMBL5288492)Show SMILES CCOc1ccccc1-c1ccc(cc1)-c1nc2cnccc2c(N[C@H](CC)C(=O)NS(=O)(=O)C2CC2)c1C#N |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
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More data for this
Ligand-Target Pair | |
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
(Homo sapiens) | BDBM50611050
(CHEMBL5270765)Show SMILES CCOc1ccccc1-c1ccc(cc1)-c1nc2cncc(Cl)c2c(N[C@H](CC)C(N)=O)c1C#N |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
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UniChem
| | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
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More data for this
Ligand-Target Pair | |
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
(Homo sapiens) | BDBM50611020
(CHEMBL5282226)Show SMILES CC[C@@H](Nc1c(C#N)c(nc2cnccc12)-c1ccc(cc1)-c1ccccc1F)C(N)=O |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
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UniChem
| | n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
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More data for this
Ligand-Target Pair | |
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
(Homo sapiens) | BDBM50611012
(CHEMBL5284796)Show SMILES CCOc1ccccc1-c1ccc(cc1)-c1nc2cnccc2c(N[C@H](CC)C(=O)NS(C)(=O)=O)c1C#N |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
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More data for this
Ligand-Target Pair | |
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
(Homo sapiens) | BDBM50615191
(CHEMBL5271804)Show SMILES CN1C(=O)[C@@H](CC2CCCC2)N(C2CCCC2)c2nc(Nc3cc(Cl)c(O)c(Cl)c3)ncc12 |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
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UniChem
| | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
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More data for this
Ligand-Target Pair | |
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
(Homo sapiens) | BDBM50611023
(CHEMBL5273876)Show SMILES CC[C@@H](Nc1c(C#N)c(nc2cnccc12)-c1ccc(cc1)-c1ccccc1OC)C(N)=O |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
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More data for this
Ligand-Target Pair | |
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
(Homo sapiens) | BDBM50611043
(CHEMBL5272762)Show SMILES CC[C@@H](Nc1c(C#N)c(nc2cnccc12)-c1ccc(cc1)-c1ccc(F)cc1OC)C(N)=O |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 47 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this
Ligand-Target Pair | |
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
(Homo sapiens) | BDBM50610996
(CHEMBL5271652)Show SMILES CCOc1ccccc1-c1ccc(cc1)-c1nc2cnccc2c(NC(C)C(O)=O)c1C#N | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 51 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this
Ligand-Target Pair | |
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
(Homo sapiens) | BDBM50610997
(CHEMBL5276719)Show SMILES CCOc1ccccc1-c1ccc(cc1)-c1nc2cnccc2c(N[C@H](CC)C(O)=O)c1C#N |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 59 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this
Ligand-Target Pair | |
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
(Homo sapiens) | BDBM50611033
(CHEMBL5265849)Show SMILES CC[C@@H](Nc1c(C#N)c(nc2cnccc12)-c1ccc(cc1)-c1cccc(C)c1)C(N)=O |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 61 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this
Ligand-Target Pair | |
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
(Homo sapiens) | BDBM50610998
(CHEMBL5274835)Show SMILES CC[C@@H](Nc1c(C#N)c(nc2cnccc12)-c1ccc(Br)cc1)C(O)=O |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 66 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this
Ligand-Target Pair | |
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
(Homo sapiens) | BDBM50611046
(CHEMBL5290005)Show SMILES CC[C@@H](Nc1c(C#N)c(nc2cnccc12)-c1ccc(cc1)-c1cccc(Cl)c1F)C(N)=O |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
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PDB
UniChem
| PDB
| n/a | n/a | 69 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
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More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
(Homo sapiens) | BDBM50611047
(CHEMBL5277824)Show SMILES CC[C@@H](Nc1c(C#N)c(nc2cnccc12)-c1ccc(cc1)-c1cccc(C)c1F)C(N)=O |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 71 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this
Ligand-Target Pair | |
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
(Homo sapiens) | BDBM50611032
(CHEMBL5275703)Show SMILES CC[C@@H](Nc1c(C#N)c(nc2cnccc12)-c1ccc(cc1)-c1cccc(Cl)c1)C(N)=O |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 74 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
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More data for this
Ligand-Target Pair | |
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
(Homo sapiens) | BDBM50611036
(CHEMBL5288989)Show SMILES CC[C@@H](Nc1c(C#N)c(nc2cnccc12)-c1ccc(cc1)-c1ccc(F)cc1)C(N)=O |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 88 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this
Ligand-Target Pair | |
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
(Homo sapiens) | BDBM50611005
(CHEMBL5273777)Show SMILES CCOc1ccccc1-c1ccc(cc1)-c1nc2cnccc2c(N[C@H](CC)C(N)=O)c1C#N |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 89 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this
Ligand-Target Pair | |
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
(Homo sapiens) | BDBM50611022
(CHEMBL5286700)Show SMILES CC[C@@H](Nc1c(C#N)c(nc2cnccc12)-c1ccc(cc1)-c1ccccc1C)C(N)=O |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this
Ligand-Target Pair | |
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
(Homo sapiens) | BDBM50611046
(CHEMBL5290005)Show SMILES CC[C@@H](Nc1c(C#N)c(nc2cnccc12)-c1ccc(cc1)-c1cccc(Cl)c1F)C(N)=O |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
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PDB
UniChem
| PDB
| n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
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More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
(Homo sapiens) | BDBM50527943
(CHEMBL4447308)Show SMILES CS(=O)(=O)Nc1ccc(cc1)-c1cncc(\C=C2/SC(=O)NC2=O)c1 Show InChI InChI=1S/C16H13N3O4S2/c1-25(22,23)19-13-4-2-11(3-5-13)12-6-10(8-17-9-12)7-14-15(20)18-16(21)24-14/h2-9,19H,1H3,(H,18,20,21)/b14-7- | PDB
UniProtKB/SwissProt
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UniChem
| Article
PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Dana-Farber Cancer Institute
Curated by ChEMBL
| Assay Description
Inhibition of GST-tagged recombinant PI5P4Kalpha (unknown origin) incubated for 1 hr in presence of DPPS and PI5P by ADP-Glo assay |
J Med Chem 63: 4880-4895 (2020)
Article DOI: 10.1021/acs.jmedchem.0c00227
BindingDB Entry DOI: 10.7270/Q2SB4964 |
More data for this
Ligand-Target Pair | |
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
(Homo sapiens) | BDBM50611013
(CHEMBL5288492)Show SMILES CCOc1ccccc1-c1ccc(cc1)-c1nc2cnccc2c(N[C@H](CC)C(=O)NS(=O)(=O)C2CC2)c1C#N |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this
Ligand-Target Pair | |
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
(Homo sapiens) | BDBM50611012
(CHEMBL5284796)Show SMILES CCOc1ccccc1-c1ccc(cc1)-c1nc2cnccc2c(N[C@H](CC)C(=O)NS(C)(=O)=O)c1C#N |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this
Ligand-Target Pair | |
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
(Homo sapiens) | BDBM50611021
(CHEMBL5277327)Show SMILES CC[C@@H](Nc1c(C#N)c(nc2cnccc12)-c1ccc(cc1)-c1ccccc1Cl)C(N)=O |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this
Ligand-Target Pair | |
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
(Homo sapiens) | BDBM50611047
(CHEMBL5277824)Show SMILES CC[C@@H](Nc1c(C#N)c(nc2cnccc12)-c1ccc(cc1)-c1cccc(C)c1F)C(N)=O |r| | PDB
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Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
(Homo sapiens) | BDBM50611031
(CHEMBL5266303)Show SMILES CC[C@@H](Nc1c(C#N)c(nc2cnccc12)-c1ccc(cc1)-c1cccc(F)c1)C(N)=O |r| | PDB
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Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
(Homo sapiens) | BDBM50610997
(CHEMBL5276719)Show SMILES CCOc1ccccc1-c1ccc(cc1)-c1nc2cnccc2c(N[C@H](CC)C(O)=O)c1C#N |r| | PDB
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Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
(Homo sapiens) | BDBM50611016
(CHEMBL5288398)Show SMILES CCOc1ccccc1-c1ccc(cc1)-c1nc2cnccc2c(C[C@H](C)C(O)=O)c1C#N |r| | PDB
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Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
(Homo sapiens) | BDBM50611034
(CHEMBL5282526)Show SMILES CC[C@@H](Nc1c(C#N)c(nc2cnccc12)-c1ccc(cc1)-c1cccc(OC)c1)C(N)=O |r| | PDB
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Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
(Homo sapiens) | BDBM50611038
(CHEMBL5289817)Show SMILES CC[C@@H](Nc1c(C#N)c(nc2cnccc12)-c1ccc(cc1)-c1ccc(OC)cc1)C(N)=O |r| | PDB
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Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
(Homo sapiens) | BDBM6309
(6-Acetyl-8-cyclopentyl-5-methyl-2-(5-piperazin-1-y...)Show SMILES CC(=O)c1c(C)c2cnc(Nc3ccc(cn3)N3CCNCC3)nc2n(C2CCCC2)c1=O Show InChI InChI=1S/C24H29N7O2/c1-15-19-14-27-24(28-20-8-7-18(13-26-20)30-11-9-25-10-12-30)29-22(19)31(17-5-3-4-6-17)23(33)21(15)16(2)32/h7-8,13-14,17,25H,3-6,9-12H2,1-2H3,(H,26,27,28,29) | PDB
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3D Structure (crystal) |
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
(Homo sapiens) | BDBM50611050
(CHEMBL5270765)Show SMILES CCOc1ccccc1-c1ccc(cc1)-c1nc2cncc(Cl)c2c(N[C@H](CC)C(N)=O)c1C#N |r| | PDB
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Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
(Homo sapiens) | BDBM50611020
(CHEMBL5282226)Show SMILES CC[C@@H](Nc1c(C#N)c(nc2cnccc12)-c1ccc(cc1)-c1ccccc1F)C(N)=O |r| | PDB
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Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
(Homo sapiens) | BDBM50611043
(CHEMBL5272762)Show SMILES CC[C@@H](Nc1c(C#N)c(nc2cnccc12)-c1ccc(cc1)-c1ccc(F)cc1OC)C(N)=O |r| | PDB
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Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
(Homo sapiens) | BDBM50611032
(CHEMBL5275703)Show SMILES CC[C@@H](Nc1c(C#N)c(nc2cnccc12)-c1ccc(cc1)-c1cccc(Cl)c1)C(N)=O |r| | PDB
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Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
(Homo sapiens) | BDBM50611026
(CHEMBL5270656)Show SMILES CC[C@@H](Nc1c(C#N)c(nc2cnccc12)-c1ccc(cc1)-c1ccccc1NC)C(N)=O |r| | PDB
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