Compile Data Set for Download or QSAR

Found 4 hits of ic50 for UniProtKB: P06681   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Complement C2 (Homo sapiens)	BDBM50462097 (CHEMBL4247125) Show SMILES CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C=O |r| Show InChI InChI=1S/C35H66N12O7/c1-19(2)15-26(31(52)42-22(7)29(50)44-24(18-48)11-9-13-40-34(36)37)46-33(54)28(17-21(5)6)47-32(53)27(16-20(3)4)45-30(51)25(43-23(8)49)12-10-14-41-35(38)39/h18-22,24-28H,9-17H2,1-8H3,(H,42,52)(H,43,49)(H,44,50)(H,45,51)(H,46,54)(H,47,53)(H4,36,37,40)(H4,38,39,41)/t22-,24-,25-,26-,27-,28-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Competitive/reversible inhibition of human C2 using Ac-SHLGLAR-pNA as substrate				J Med Chem 61: 3253-3276 (2018) Article DOI: 10.1021/acs.jmedchem.7b00882 BindingDB Entry DOI: 10.7270/Q2MK6GJ9
					More data for this Ligand-Target Pair
Complement C2 (Homo sapiens)	BDBM50462097 (CHEMBL4247125) Show SMILES CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C=O |r| Show InChI InChI=1S/C35H66N12O7/c1-19(2)15-26(31(52)42-22(7)29(50)44-24(18-48)11-9-13-40-34(36)37)46-33(54)28(17-21(5)6)47-32(53)27(16-20(3)4)45-30(51)25(43-23(8)49)12-10-14-41-35(38)39/h18-22,24-28H,9-17H2,1-8H3,(H,42,52)(H,43,49)(H,44,50)(H,45,51)(H,46,54)(H,47,53)(H4,36,37,40)(H4,38,39,41)/t22-,24-,25-,26-,27-,28-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Inhibition of human C2-mediated C3 processing after 24 hrs by SDS-PAGE				J Med Chem 61: 3253-3276 (2018) Article DOI: 10.1021/acs.jmedchem.7b00882 BindingDB Entry DOI: 10.7270/Q2MK6GJ9
					More data for this Ligand-Target Pair
Complement C2 (Homo sapiens)	BDBM50462097 (CHEMBL4247125) Show SMILES CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C=O |r| Show InChI InChI=1S/C35H66N12O7/c1-19(2)15-26(31(52)42-22(7)29(50)44-24(18-48)11-9-13-40-34(36)37)46-33(54)28(17-21(5)6)47-32(53)27(16-20(3)4)45-30(51)25(43-23(8)49)12-10-14-41-35(38)39/h18-22,24-28H,9-17H2,1-8H3,(H,42,52)(H,43,49)(H,44,50)(H,45,51)(H,46,54)(H,47,53)(H4,36,37,40)(H4,38,39,41)/t22-,24-,25-,26-,27-,28-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Inhibition of C2-mediated MAC formation in human serum by ELISA				J Med Chem 61: 3253-3276 (2018) Article DOI: 10.1021/acs.jmedchem.7b00882 BindingDB Entry DOI: 10.7270/Q2MK6GJ9
					More data for this Ligand-Target Pair
Complement C2 (Homo sapiens)	BDBM50462097 (CHEMBL4247125) Show SMILES CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C=O |r| Show InChI InChI=1S/C35H66N12O7/c1-19(2)15-26(31(52)42-22(7)29(50)44-24(18-48)11-9-13-40-34(36)37)46-33(54)28(17-21(5)6)47-32(53)27(16-20(3)4)45-30(51)25(43-23(8)49)12-10-14-41-35(38)39/h18-22,24-28H,9-17H2,1-8H3,(H,42,52)(H,43,49)(H,44,50)(H,45,51)(H,46,54)(H,47,53)(H4,36,37,40)(H4,38,39,41)/t22-,24-,25-,26-,27-,28-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Inhibition of human serum C2-mediated lysis of antibody-sensitized sheep red blood cells after 30 mins by UV-Vis spectrophotometric method				J Med Chem 61: 3253-3276 (2018) Article DOI: 10.1021/acs.jmedchem.7b00882 BindingDB Entry DOI: 10.7270/Q2MK6GJ9
					More data for this Ligand-Target Pair