Compile Data Set for Download or QSAR

Found 3 hits of ic50 for UniProtKB: A4D1B5   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gamma-secretase-activating protein (Homo sapiens (Human))	BDBM157135 (US9023767, GSI-34) Show SMILES Fc1ccc(OCC(=O)Nc2ccc3CC4CCC(Cc3c2)C4NS(=O)(=O)c2ccc(Cl)s2)cc1 Show InChI InChI=1S/C25H24ClFN2O4S2/c26-22-9-10-24(34-22)35(31,32)29-25-16-1-2-17(25)12-18-13-20(6-3-15(18)11-16)28-23(30)14-33-21-7-4-19(27)5-8-21/h3-10,13,16-17,25,29H,1-2,11-12,14H2,(H,28,30)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Memorial Sloan-Kettering Cancer Center US Patent					Assay Description Among the advantages of this Abeta 42 HTRF gamma-secretase assay is the construction of the biotinylated, recombinant CT6-I45F substrate, which has p...				US Patent US9023767 (2015) BindingDB Entry DOI: 10.7270/Q2Z60MS4
					More data for this Ligand-Target Pair
Gamma-secretase-activating protein (Homo sapiens (Human))	BDBM157134 (US9023767, Compound E) Show SMILES CC(NC(=O)Cc1cc(F)cc(F)c1)C(=O)NC1N=C(c2ccccc2)c2ccccc2N(C)C1=O |t:19| Show InChI InChI=1S/C27H24F2N4O3/c1-16(30-23(34)14-17-12-19(28)15-20(29)13-17)26(35)32-25-27(36)33(2)22-11-7-6-10-21(22)24(31-25)18-8-4-3-5-9-18/h3-13,15-16,25H,14H2,1-2H3,(H,30,34)(H,32,35)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Memorial Sloan-Kettering Cancer Center US Patent					Assay Description Among the advantages of this Abeta 42 HTRF gamma-secretase assay is the construction of the biotinylated, recombinant CT6-I45F substrate, which has p...				US Patent US9023767 (2015) BindingDB Entry DOI: 10.7270/Q2Z60MS4
					More data for this Ligand-Target Pair
Gamma-secretase-activating protein (Homo sapiens (Human))	BDBM50458159 (Nirogacestat | PF 03084014 | PF 3084014 | PF-03084...) Show SMILES CCC[C@H](N[C@H]1CCc2cc(F)cc(F)c2C1)C(=O)Nc1cn(cn1)C(C)(C)CNCC(C)(C)C |r| Show InChI InChI=1S/C27H41F2N5O/c1-7-8-23(32-20-10-9-18-11-19(28)12-22(29)21(18)13-20)25(35)33-24-14-34(17-31-24)27(5,6)16-30-15-26(2,3)4/h11-12,14,17,20,23,30,32H,7-10,13,15-16H2,1-6H3,(H,33,35)/t20-,23-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem		n/a	n/a	6.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibitory activity against FAAH in Wistar rat brain homogenate				Citation and Details
					More data for this Ligand-Target Pair