Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Non-receptor tyrosine-protein kinase TYK2 [870-1187] (Homo sapiens (Human)) | BDBM185700 (US10875847, Compound Oclacitinib | US9161939, 1a |...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 75.1 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Zoetis Services LLC US Patent | Assay Description Methods: A peptide mobility shift assay was used to quantify the phosphorylation of the JAKtide (JAK-2 and JAK-3) or the IRS-1 peptide (JAK-1 and Tyk... | US Patent US9271981 (2016) BindingDB Entry DOI: 10.7270/Q2VD6X90 | |||||||||||
More data for this Ligand-Target Pair |