Found 3 hits of ki for UniProtKB: P31751 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
RAC-alpha/RAC-beta/RAC-gamma serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM50205472
((5Z)-5-(quinolin-6-ylmethylidene)-2-[(thiophen-2-y...)Show SMILES O=C1N=C(NCc2cccs2)SC1=Cc1ccc2ncccc2c1 |w:13.15,t:2| Show InChI InChI=1S/C18H13N3OS2/c22-17-16(24-18(21-17)20-11-14-4-2-8-23-14)10-12-5-6-15-13(9-12)3-1-7-19-15/h1-10H,11H2,(H,20,21,22) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| >2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Roche Research Center
Curated by ChEMBL
| Assay Description Inhibition of AKT |
Bioorg Med Chem Lett 17: 2134-8 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.081 BindingDB Entry DOI: 10.7270/Q2BV7G9T |
More data for this Ligand-Target Pair | |
RAC-alpha/RAC-beta/RAC-gamma serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM50205477
((Z)-2-((1R,2S)-2-phenylcyclopropylamino)-5-(quinol...)Show SMILES O=C1N=C(N[C@@H]2C[C@H]2c2ccccc2)SC1=Cc1ccc2ncccc2c1 |w:16.19,t:2| Show InChI InChI=1S/C22H17N3OS/c26-21-20(12-14-8-9-18-16(11-14)7-4-10-23-18)27-22(25-21)24-19-13-17(19)15-5-2-1-3-6-15/h1-12,17,19H,13H2,(H,24,25,26)/t17-,19+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| >2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Roche Research Center
Curated by ChEMBL
| Assay Description Inhibition of AKT |
Bioorg Med Chem Lett 17: 2134-8 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.081 BindingDB Entry DOI: 10.7270/Q2BV7G9T |
More data for this Ligand-Target Pair | |
RAC-alpha/RAC-beta/RAC-gamma serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM50205468
((Z)-2-amino-5-(quinolin-6-ylmethylene)thiazol-4(5H...)Show SMILES NC1=NC(=O)C(S1)=Cc1ccc2ncccc2c1 |w:7.8,t:1| Show InChI InChI=1S/C13H9N3OS/c14-13-16-12(17)11(18-13)7-8-3-4-10-9(6-8)2-1-5-15-10/h1-7H,(H2,14,16,17) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| >2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Roche Research Center
Curated by ChEMBL
| Assay Description Inhibition of AKT |
Bioorg Med Chem Lett 17: 2134-8 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.081 BindingDB Entry DOI: 10.7270/Q2BV7G9T |
More data for this Ligand-Target Pair | |