Compile Data Set for Download or QSAR

Found 316 hits Enz. Inhib. hit(s) with all data for entry = 10305   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mast/stem cell growth factor receptor Kit [V560G,D816V] (Homo sapiens (Human))	BDBM175424 (US9688680, 24) Show SMILES Cc1c(cnn1C)-c1cc2c(ncnn2c1)N1CC(C1)C(=O)NCc1ccc(C)cc1 Show InChI InChI=1S/C23H25N7O/c1-15-4-6-17(7-5-15)9-24-23(31)19-11-29(12-19)22-21-8-18(13-30(21)27-14-25-22)20-10-26-28(3)16(20)2/h4-8,10,13-14,19H,9,11-12H2,1-3H3,(H,24,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	25
BLUEPRINT MEDICINES CORPORATION US Patent					Assay Description 10,000 HMC1.2 cells were incubated in 22 ul culture media (phenol-red free IMDM, no serum) in each well of a 384-well plate and serum starved overnig...				US Patent US9688680 (2017) BindingDB Entry DOI: 10.7270/Q2NV9GDQ
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit [V560G,D816V] (Homo sapiens (Human))	BDBM175425 (US9688680, 25) Show SMILES Cc1nn(C)cc1-c1cc2c(ncnn2c1)N1CC(C1)C(=O)NCc1ccc(C)cc1 Show InChI InChI=1S/C23H25N7O/c1-15-4-6-17(7-5-15)9-24-23(31)19-10-29(11-19)22-21-8-18(12-30(21)26-14-25-22)20-13-28(3)27-16(20)2/h4-8,12-14,19H,9-11H2,1-3H3,(H,24,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	25
BLUEPRINT MEDICINES CORPORATION US Patent					Assay Description 10,000 HMC1.2 cells were incubated in 22 ul culture media (phenol-red free IMDM, no serum) in each well of a 384-well plate and serum starved overnig...				US Patent US9688680 (2017) BindingDB Entry DOI: 10.7270/Q2NV9GDQ
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit [V560G,D816V] (Homo sapiens (Human))	BDBM175426 (US9688680, 26) Show SMILES Cc1ccc(CNC(=O)C2(C)CN(C2)c2ncnn3cc(cc23)-c2cnn(C)c2)cc1 Show InChI InChI=1S/C23H25N7O/c1-16-4-6-17(7-5-16)9-24-22(31)23(2)13-29(14-23)21-20-8-18(12-30(20)27-15-25-21)19-10-26-28(3)11-19/h4-8,10-12,15H,9,13-14H2,1-3H3,(H,24,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	25
BLUEPRINT MEDICINES CORPORATION US Patent					Assay Description 10,000 HMC1.2 cells were incubated in 22 ul culture media (phenol-red free IMDM, no serum) in each well of a 384-well plate and serum starved overnig...				US Patent US9688680 (2017) BindingDB Entry DOI: 10.7270/Q2NV9GDQ
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit [V560G,D816V] (Homo sapiens (Human))	BDBM175428 (US9688680, 28) Show SMILES CCc1ccc(CNC(=O)C2CN(C2)c2ncnn3cc(cc23)-c2cnn(C)c2)cc1 Show InChI InChI=1S/C23H25N7O/c1-3-16-4-6-17(7-5-16)9-24-23(31)20-12-29(13-20)22-21-8-18(14-30(21)27-15-25-22)19-10-26-28(2)11-19/h4-8,10-11,14-15,20H,3,9,12-13H2,1-2H3,(H,24,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	25
BLUEPRINT MEDICINES CORPORATION US Patent					Assay Description 10,000 HMC1.2 cells were incubated in 22 ul culture media (phenol-red free IMDM, no serum) in each well of a 384-well plate and serum starved overnig...				US Patent US9688680 (2017) BindingDB Entry DOI: 10.7270/Q2NV9GDQ
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit [V560G,D816V] (Homo sapiens (Human))	BDBM175429 (US9688680, 29) Show SMILES Cc1ccc(CNC(=O)C2CN(C2)c2ncnn3cc(cc23)-c2cn(C)nc2N)cc1 Show InChI InChI=1S/C22H24N8O/c1-14-3-5-15(6-4-14)8-24-22(31)17-9-29(10-17)21-19-7-16(11-30(19)26-13-25-21)18-12-28(2)27-20(18)23/h3-7,11-13,17H,8-10H2,1-2H3,(H2,23,27)(H,24,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	25
BLUEPRINT MEDICINES CORPORATION US Patent					Assay Description 10,000 HMC1.2 cells were incubated in 22 ul culture media (phenol-red free IMDM, no serum) in each well of a 384-well plate and serum starved overnig...				US Patent US9688680 (2017) BindingDB Entry DOI: 10.7270/Q2NV9GDQ
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit [V560G,D816V] (Homo sapiens (Human))	BDBM175433 (US9688680, 33) Show SMILES Cc1csc(c1)-c1cc2c(ncnn2c1)N1CC(C1)C(=O)NCc1ccc(C)cc1 Show InChI InChI=1S/C23H23N5OS/c1-15-3-5-17(6-4-15)9-24-23(29)19-10-27(11-19)22-20-8-18(12-28(20)26-14-25-22)21-7-16(2)13-30-21/h3-8,12-14,19H,9-11H2,1-2H3,(H,24,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	25
BLUEPRINT MEDICINES CORPORATION US Patent					Assay Description 10,000 HMC1.2 cells were incubated in 22 ul culture media (phenol-red free IMDM, no serum) in each well of a 384-well plate and serum starved overnig...				US Patent US9688680 (2017) BindingDB Entry DOI: 10.7270/Q2NV9GDQ
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit [V560G,D816V] (Homo sapiens (Human))	BDBM175434 (US9688680, 34) Show SMILES Cc1ccc(s1)-c1cc2c(ncnn2c1)N1CC(C1)C(=O)NCc1ccc(C)cc1 Show InChI InChI=1S/C23H23N5OS/c1-15-3-6-17(7-4-15)10-24-23(29)19-11-27(12-19)22-20-9-18(13-28(20)26-14-25-22)21-8-5-16(2)30-21/h3-9,13-14,19H,10-12H2,1-2H3,(H,24,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	25
BLUEPRINT MEDICINES CORPORATION US Patent					Assay Description 10,000 HMC1.2 cells were incubated in 22 ul culture media (phenol-red free IMDM, no serum) in each well of a 384-well plate and serum starved overnig...				US Patent US9688680 (2017) BindingDB Entry DOI: 10.7270/Q2NV9GDQ
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit [V560G,D816V] (Homo sapiens (Human))	BDBM175435 (US9688680, 35) Show SMILES C[C@H](NC(=O)C1CN(C1)c1ncnn2cc(cc12)-c1cnn(C)c1)c1ccc(F)cc1 |r| Show InChI InChI=1S/C22H22FN7O/c1-14(15-3-5-19(23)6-4-15)27-22(31)18-10-29(11-18)21-20-7-16(12-30(20)26-13-24-21)17-8-25-28(2)9-17/h3-9,12-14,18H,10-11H2,1-2H3,(H,27,31)/t14-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	25
BLUEPRINT MEDICINES CORPORATION US Patent					Assay Description 10,000 HMC1.2 cells were incubated in 22 ul culture media (phenol-red free IMDM, no serum) in each well of a 384-well plate and serum starved overnig...				US Patent US9688680 (2017) BindingDB Entry DOI: 10.7270/Q2NV9GDQ
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit [V560G,D816V] (Homo sapiens (Human))	BDBM175436 (US9688680, 36) Show SMILES Cc1ccc(CNC(=O)C2CN(C2)c2ncnn3cc(cc23)-c2cnn(C)c2)c(F)c1 Show InChI InChI=1S/C22H22FN7O/c1-14-3-4-15(19(23)5-14)7-24-22(31)18-10-29(11-18)21-20-6-16(12-30(20)27-13-25-21)17-8-26-28(2)9-17/h3-6,8-9,12-13,18H,7,10-11H2,1-2H3,(H,24,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	25
BLUEPRINT MEDICINES CORPORATION US Patent					Assay Description 10,000 HMC1.2 cells were incubated in 22 ul culture media (phenol-red free IMDM, no serum) in each well of a 384-well plate and serum starved overnig...				US Patent US9688680 (2017) BindingDB Entry DOI: 10.7270/Q2NV9GDQ
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit [V560G,D816V] (Homo sapiens (Human))	BDBM175438 (US9688680, 38) Show SMILES Cn1cc(cn1)-c1cc2c(ncnn2c1)N1CC(C1)C(=O)NCc1ccc(Cl)cc1 Show InChI InChI=1S/C21H20ClN7O/c1-27-9-16(8-25-27)15-6-19-20(24-13-26-29(19)12-15)28-10-17(11-28)21(30)23-7-14-2-4-18(22)5-3-14/h2-6,8-9,12-13,17H,7,10-11H2,1H3,(H,23,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	25
BLUEPRINT MEDICINES CORPORATION US Patent					Assay Description 10,000 HMC1.2 cells were incubated in 22 ul culture media (phenol-red free IMDM, no serum) in each well of a 384-well plate and serum starved overnig...				US Patent US9688680 (2017) BindingDB Entry DOI: 10.7270/Q2NV9GDQ
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit [V560G,D816V] (Homo sapiens (Human))	BDBM175439 (US9688680, 39) Show SMILES Cn1cc(cn1)-c1cc2c(ncnn2c1)N1CC(C1)NC(=O)Cc1ccc(Cl)cc1 Show InChI InChI=1S/C21H20ClN7O/c1-27-9-16(8-24-27)15-7-19-21(23-13-25-29(19)10-15)28-11-18(12-28)26-20(30)6-14-2-4-17(22)5-3-14/h2-5,7-10,13,18H,6,11-12H2,1H3,(H,26,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	25
BLUEPRINT MEDICINES CORPORATION US Patent					Assay Description 10,000 HMC1.2 cells were incubated in 22 ul culture media (phenol-red free IMDM, no serum) in each well of a 384-well plate and serum starved overnig...				US Patent US9688680 (2017) BindingDB Entry DOI: 10.7270/Q2NV9GDQ
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit [V560G,D816V] (Homo sapiens (Human))	BDBM175443 (US9688680, 43) Show SMILES CC(C)n1cc(cn1)-c1cc2c(ncnn2c1)N1CC(C1)C(=O)Nc1ccc(cc1)C#N Show InChI InChI=1S/C23H22N8O/c1-15(2)30-13-18(9-26-30)17-7-21-22(25-14-27-31(21)12-17)29-10-19(11-29)23(32)28-20-5-3-16(8-24)4-6-20/h3-7,9,12-15,19H,10-11H2,1-2H3,(H,28,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	25
BLUEPRINT MEDICINES CORPORATION US Patent					Assay Description 10,000 HMC1.2 cells were incubated in 22 ul culture media (phenol-red free IMDM, no serum) in each well of a 384-well plate and serum starved overnig...				US Patent US9688680 (2017) BindingDB Entry DOI: 10.7270/Q2NV9GDQ
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit [V560G,D816V] (Homo sapiens (Human))	BDBM175445 (US9688680, 45) Show SMILES COc1ccc(cc1)-c1cc2c(ncnn2c1)N1CC(C1)C(=O)NCc1ccc(C)cc1 Show InChI InChI=1S/C25H25N5O2/c1-17-3-5-18(6-4-17)12-26-25(31)21-13-29(14-21)24-23-11-20(15-30(23)28-16-27-24)19-7-9-22(32-2)10-8-19/h3-11,15-16,21H,12-14H2,1-2H3,(H,26,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	25
BLUEPRINT MEDICINES CORPORATION US Patent					Assay Description 10,000 HMC1.2 cells were incubated in 22 ul culture media (phenol-red free IMDM, no serum) in each well of a 384-well plate and serum starved overnig...				US Patent US9688680 (2017) BindingDB Entry DOI: 10.7270/Q2NV9GDQ
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit [V560G,D816V] (Homo sapiens (Human))	BDBM175446 (US9688680, 46) Show SMILES COc1cccc(c1)-c1cc2c(ncnn2c1)N1CC(C1)C(=O)NCc1ccc(C)cc1 Show InChI InChI=1S/C25H25N5O2/c1-17-6-8-18(9-7-17)12-26-25(31)21-13-29(14-21)24-23-11-20(15-30(23)28-16-27-24)19-4-3-5-22(10-19)32-2/h3-11,15-16,21H,12-14H2,1-2H3,(H,26,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	25
BLUEPRINT MEDICINES CORPORATION US Patent					Assay Description 10,000 HMC1.2 cells were incubated in 22 ul culture media (phenol-red free IMDM, no serum) in each well of a 384-well plate and serum starved overnig...				US Patent US9688680 (2017) BindingDB Entry DOI: 10.7270/Q2NV9GDQ
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit [V560G,D816V] (Homo sapiens (Human))	BDBM175448 (US9688680, 48) Show SMILES Cn1cc(cn1)-c1cc2c(ncnn2c1)N1CC(C1)C(=O)NCc1ccc(cc1)C1CC1 Show InChI InChI=1S/C24H25N7O/c1-29-11-20(10-27-29)19-8-22-23(26-15-28-31(22)14-19)30-12-21(13-30)24(32)25-9-16-2-4-17(5-3-16)18-6-7-18/h2-5,8,10-11,14-15,18,21H,6-7,9,12-13H2,1H3,(H,25,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	25
BLUEPRINT MEDICINES CORPORATION US Patent					Assay Description 10,000 HMC1.2 cells were incubated in 22 ul culture media (phenol-red free IMDM, no serum) in each well of a 384-well plate and serum starved overnig...				US Patent US9688680 (2017) BindingDB Entry DOI: 10.7270/Q2NV9GDQ
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit [V560G,D816V] (Homo sapiens (Human))	BDBM175450 (US9688680, 50) Show SMILES COc1ccc(cn1)-c1cc2c(ncnn2c1)N1CC(C1)C(=O)NCc1ccc(C)cc1 Show InChI InChI=1S/C24H24N6O2/c1-16-3-5-17(6-4-16)10-26-24(31)20-12-29(13-20)23-21-9-19(14-30(21)28-15-27-23)18-7-8-22(32-2)25-11-18/h3-9,11,14-15,20H,10,12-13H2,1-2H3,(H,26,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	25
BLUEPRINT MEDICINES CORPORATION US Patent					Assay Description 10,000 HMC1.2 cells were incubated in 22 ul culture media (phenol-red free IMDM, no serum) in each well of a 384-well plate and serum starved overnig...				US Patent US9688680 (2017) BindingDB Entry DOI: 10.7270/Q2NV9GDQ
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit [V560G,D816V] (Homo sapiens (Human))	BDBM175456 (US9688680, 56) Show SMILES CC[C@H](NC(=O)C1CN(C1)c1ncnn2cc(cc12)-c1cnn(C)c1)c1ccc(C)cc1 |r| Show InChI InChI=1S/C24H27N7O/c1-4-21(17-7-5-16(2)6-8-17)28-24(32)20-12-30(13-20)23-22-9-18(14-31(22)27-15-25-23)19-10-26-29(3)11-19/h5-11,14-15,20-21H,4,12-13H2,1-3H3,(H,28,32)/t21-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	25
BLUEPRINT MEDICINES CORPORATION US Patent					Assay Description 10,000 HMC1.2 cells were incubated in 22 ul culture media (phenol-red free IMDM, no serum) in each well of a 384-well plate and serum starved overnig...				US Patent US9688680 (2017) BindingDB Entry DOI: 10.7270/Q2NV9GDQ
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit [V560G,D816V] (Homo sapiens (Human))	BDBM175457 (US9688680, 57) Show SMILES Cc1ccc(CNC(=O)C2(CN)CN(C2)c2ncnn3cc(cc23)-c2cnn(C)c2)cc1 Show InChI InChI=1S/C23H26N8O/c1-16-3-5-17(6-4-16)8-25-22(32)23(12-24)13-30(14-23)21-20-7-18(11-31(20)28-15-26-21)19-9-27-29(2)10-19/h3-7,9-11,15H,8,12-14,24H2,1-2H3,(H,25,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	25
BLUEPRINT MEDICINES CORPORATION US Patent					Assay Description 10,000 HMC1.2 cells were incubated in 22 ul culture media (phenol-red free IMDM, no serum) in each well of a 384-well plate and serum starved overnig...				US Patent US9688680 (2017) BindingDB Entry DOI: 10.7270/Q2NV9GDQ
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit [V560G,D816V] (Homo sapiens (Human))	BDBM175460 (US9688680, 60) Show SMILES COC1(CN(C1)c1ncnn2cc(cc12)-c1cnn(C)c1)C(=O)NCc1ccc(C)cc1 Show InChI InChI=1S/C23H25N7O2/c1-16-4-6-17(7-5-16)9-24-22(31)23(32-3)13-29(14-23)21-20-8-18(12-30(20)27-15-25-21)19-10-26-28(2)11-19/h4-8,10-12,15H,9,13-14H2,1-3H3,(H,24,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	25
BLUEPRINT MEDICINES CORPORATION US Patent					Assay Description 10,000 HMC1.2 cells were incubated in 22 ul culture media (phenol-red free IMDM, no serum) in each well of a 384-well plate and serum starved overnig...				US Patent US9688680 (2017) BindingDB Entry DOI: 10.7270/Q2NV9GDQ
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit [V560G,D816V] (Homo sapiens (Human))	BDBM175461 (US9688680, 61) Show SMILES Cc1ccc(CNC(=O)C2CN(C2)c2ncnn3cc(cc23)-c2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C24H22ClN5O/c1-16-2-4-17(5-3-16)11-26-24(31)20-12-29(13-20)23-22-10-19(14-30(22)28-15-27-23)18-6-8-21(25)9-7-18/h2-10,14-15,20H,11-13H2,1H3,(H,26,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	25
BLUEPRINT MEDICINES CORPORATION US Patent					Assay Description 10,000 HMC1.2 cells were incubated in 22 ul culture media (phenol-red free IMDM, no serum) in each well of a 384-well plate and serum starved overnig...				US Patent US9688680 (2017) BindingDB Entry DOI: 10.7270/Q2NV9GDQ
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit [V560G,D816V] (Homo sapiens (Human))	BDBM175463 (US9688680, 63) Show SMILES Cc1nc(C)c(s1)-c1cc2c(ncnn2c1)N1CC(C1)C(=O)NCc1ccc(C)cc1 Show InChI InChI=1S/C23H24N6OS/c1-14-4-6-17(7-5-14)9-24-23(30)19-10-28(11-19)22-20-8-18(12-29(20)26-13-25-22)21-15(2)27-16(3)31-21/h4-8,12-13,19H,9-11H2,1-3H3,(H,24,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	25
BLUEPRINT MEDICINES CORPORATION US Patent					Assay Description 10,000 HMC1.2 cells were incubated in 22 ul culture media (phenol-red free IMDM, no serum) in each well of a 384-well plate and serum starved overnig...				US Patent US9688680 (2017) BindingDB Entry DOI: 10.7270/Q2NV9GDQ
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit [V560G,D816V] (Homo sapiens (Human))	BDBM175467 (US9688680, 67) Show SMILES COC1(CN(C1)c1ncnn2cc(cc12)C1=CCOCC1)C(=O)NCc1ccc(C)cc1 |t:18| Show InChI InChI=1S/C24H27N5O3/c1-17-3-5-18(6-4-17)12-25-23(30)24(31-2)14-28(15-24)22-21-11-20(13-29(21)27-16-26-22)19-7-9-32-10-8-19/h3-7,11,13,16H,8-10,12,14-15H2,1-2H3,(H,25,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	25
BLUEPRINT MEDICINES CORPORATION US Patent					Assay Description 10,000 HMC1.2 cells were incubated in 22 ul culture media (phenol-red free IMDM, no serum) in each well of a 384-well plate and serum starved overnig...				US Patent US9688680 (2017) BindingDB Entry DOI: 10.7270/Q2NV9GDQ
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit [V560G,D816V] (Homo sapiens (Human))	BDBM175469 (US9688680, 69) Show SMILES C[C@H](NC(=O)C1CN(C1)c1ncnn2cc(cc12)-c1cnn(C)c1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C22H22ClN7O/c1-14(15-3-5-19(23)6-4-15)27-22(31)18-10-29(11-18)21-20-7-16(12-30(20)26-13-24-21)17-8-25-28(2)9-17/h3-9,12-14,18H,10-11H2,1-2H3,(H,27,31)/t14-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	25
BLUEPRINT MEDICINES CORPORATION US Patent					Assay Description 10,000 HMC1.2 cells were incubated in 22 ul culture media (phenol-red free IMDM, no serum) in each well of a 384-well plate and serum starved overnig...				US Patent US9688680 (2017) BindingDB Entry DOI: 10.7270/Q2NV9GDQ
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit [V560G,D816V] (Homo sapiens (Human))	BDBM175473 (US9688680, 73 | US9688680, 99) Show SMILES CC[C@H](NC(=O)C1CN(C1)c1ncnn2cc(cc12)-c1cnn(C)c1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C23H24ClN7O/c1-3-20(15-4-6-19(24)7-5-15)28-23(32)18-11-30(12-18)22-21-8-16(13-31(21)27-14-25-22)17-9-26-29(2)10-17/h4-10,13-14,18,20H,3,11-12H2,1-2H3,(H,28,32)/t20-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	25
BLUEPRINT MEDICINES CORPORATION US Patent					Assay Description 10,000 HMC1.2 cells were incubated in 22 ul culture media (phenol-red free IMDM, no serum) in each well of a 384-well plate and serum starved overnig...				US Patent US9688680 (2017) BindingDB Entry DOI: 10.7270/Q2NV9GDQ
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit [V560G,D816V] (Homo sapiens (Human))	BDBM175474 (US9688680, 74) Show SMILES Cc1ccc(CNC(=O)C2CN(C2)c2ncnn3cc(cc23)-c2ccc(cc2)C2CC2)cc1 Show InChI InChI=1S/C27H27N5O/c1-18-2-4-19(5-3-18)13-28-27(33)24-14-31(15-24)26-25-12-23(16-32(25)30-17-29-26)22-10-8-21(9-11-22)20-6-7-20/h2-5,8-12,16-17,20,24H,6-7,13-15H2,1H3,(H,28,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	25
BLUEPRINT MEDICINES CORPORATION US Patent					Assay Description 10,000 HMC1.2 cells were incubated in 22 ul culture media (phenol-red free IMDM, no serum) in each well of a 384-well plate and serum starved overnig...				US Patent US9688680 (2017) BindingDB Entry DOI: 10.7270/Q2NV9GDQ
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit [V560G,D816V] (Homo sapiens (Human))	BDBM175476 (US9688680, 76) Show SMILES Cn1cc(cn1)-c1cc2c(ncnn2c1)N1CC(C1)C(=O)NCc1ccc(Cl)cc1F Show InChI InChI=1S/C21H19ClFN7O/c1-28-8-15(7-26-28)14-4-19-20(25-12-27-30(19)11-14)29-9-16(10-29)21(31)24-6-13-2-3-17(22)5-18(13)23/h2-5,7-8,11-12,16H,6,9-10H2,1H3,(H,24,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	25
BLUEPRINT MEDICINES CORPORATION US Patent					Assay Description 10,000 HMC1.2 cells were incubated in 22 ul culture media (phenol-red free IMDM, no serum) in each well of a 384-well plate and serum starved overnig...				US Patent US9688680 (2017) BindingDB Entry DOI: 10.7270/Q2NV9GDQ
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit [V560G,D816V] (Homo sapiens (Human))	BDBM175477 (US9688680, 77) Show SMILES Cn1cc(cn1)-c1cc2c(ncnn2c1)N1CC(C1)NC(=O)Cc1ccc(Cl)cc1F Show InChI InChI=1S/C21H19ClFN7O/c1-28-8-15(7-25-28)14-4-19-21(24-12-26-30(19)9-14)29-10-17(11-29)27-20(31)5-13-2-3-16(22)6-18(13)23/h2-4,6-9,12,17H,5,10-11H2,1H3,(H,27,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	25
BLUEPRINT MEDICINES CORPORATION US Patent					Assay Description 10,000 HMC1.2 cells were incubated in 22 ul culture media (phenol-red free IMDM, no serum) in each well of a 384-well plate and serum starved overnig...				US Patent US9688680 (2017) BindingDB Entry DOI: 10.7270/Q2NV9GDQ
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit [V560G,D816V] (Homo sapiens (Human))	BDBM175480 (US9688680, 80) Show SMILES CN(C)c1ccc(cn1)-c1cc2c(ncnn2c1)N1CC(C1)C(=O)NCc1ccc(C)cc1 Show InChI InChI=1S/C25H27N7O/c1-17-4-6-18(7-5-17)11-27-25(33)21-13-31(14-21)24-22-10-20(15-32(22)29-16-28-24)19-8-9-23(26-12-19)30(2)3/h4-10,12,15-16,21H,11,13-14H2,1-3H3,(H,27,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	25
BLUEPRINT MEDICINES CORPORATION US Patent					Assay Description 10,000 HMC1.2 cells were incubated in 22 ul culture media (phenol-red free IMDM, no serum) in each well of a 384-well plate and serum starved overnig...				US Patent US9688680 (2017) BindingDB Entry DOI: 10.7270/Q2NV9GDQ
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit [V560G,D816V] (Homo sapiens (Human))	BDBM175484 (US9688680, 84) Show SMILES Cn1cc(cn1)-c1cc2c(ncnn2c1)N1CC(C1)C(=O)NCc1ccc(cc1)C(C)(C)C Show InChI InChI=1S/C25H29N7O/c1-25(2,3)21-7-5-17(6-8-21)10-26-24(33)20-13-31(14-20)23-22-9-18(15-32(22)29-16-27-23)19-11-28-30(4)12-19/h5-9,11-12,15-16,20H,10,13-14H2,1-4H3,(H,26,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	25
BLUEPRINT MEDICINES CORPORATION US Patent					Assay Description 10,000 HMC1.2 cells were incubated in 22 ul culture media (phenol-red free IMDM, no serum) in each well of a 384-well plate and serum starved overnig...				US Patent US9688680 (2017) BindingDB Entry DOI: 10.7270/Q2NV9GDQ
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit [V560G,D816V] (Homo sapiens (Human))	BDBM175487 (US9688680, 87) Show SMILES CC(=O)N1CCC(=CC1)c1cc2c(ncnn2c1)N1CC(C1)C(=O)NCc1ccc(C)cc1 |c:6| Show InChI InChI=1S/C25H28N6O2/c1-17-3-5-19(6-4-17)12-26-25(33)22-13-30(14-22)24-23-11-21(15-31(23)28-16-27-24)20-7-9-29(10-8-20)18(2)32/h3-7,11,15-16,22H,8-10,12-14H2,1-2H3,(H,26,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	25
BLUEPRINT MEDICINES CORPORATION US Patent					Assay Description 10,000 HMC1.2 cells were incubated in 22 ul culture media (phenol-red free IMDM, no serum) in each well of a 384-well plate and serum starved overnig...				US Patent US9688680 (2017) BindingDB Entry DOI: 10.7270/Q2NV9GDQ
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit [V560G,D816V] (Homo sapiens (Human))	BDBM175488 (US9688680, 88) Show SMILES CNCC1(CN(C1)c1ncnn2cc(cc12)-c1cnn(C)c1)C(=O)NCc1ccc(C)cc1 Show InChI InChI=1S/C24H28N8O/c1-17-4-6-18(7-5-17)9-26-23(33)24(13-25-2)14-31(15-24)22-21-8-19(12-32(21)29-16-27-22)20-10-28-30(3)11-20/h4-8,10-12,16,25H,9,13-15H2,1-3H3,(H,26,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	25
BLUEPRINT MEDICINES CORPORATION US Patent					Assay Description 10,000 HMC1.2 cells were incubated in 22 ul culture media (phenol-red free IMDM, no serum) in each well of a 384-well plate and serum starved overnig...				US Patent US9688680 (2017) BindingDB Entry DOI: 10.7270/Q2NV9GDQ
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit [V560G,D816V] (Homo sapiens (Human))	BDBM175489 (US9688680, 89) Show SMILES CC(C)n1cc(c(N)n1)-c1cc2c(ncnn2c1)N1CC(C1)C(=O)NCc1ccc(C)cc1 Show InChI InChI=1S/C24H28N8O/c1-15(2)31-13-20(22(25)29-31)18-8-21-23(27-14-28-32(21)12-18)30-10-19(11-30)24(33)26-9-17-6-4-16(3)5-7-17/h4-8,12-15,19H,9-11H2,1-3H3,(H2,25,29)(H,26,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	25
BLUEPRINT MEDICINES CORPORATION US Patent					Assay Description 10,000 HMC1.2 cells were incubated in 22 ul culture media (phenol-red free IMDM, no serum) in each well of a 384-well plate and serum starved overnig...				US Patent US9688680 (2017) BindingDB Entry DOI: 10.7270/Q2NV9GDQ
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit [V560G,D816V] (Homo sapiens (Human))	BDBM175490 (US9688680, 90) Show SMILES Cc1ccc(cc1)[C@H](CCN)NC(=O)C1CN(C1)c1ncnn2cc(cc12)-c1cnn(C)c1 |r| Show InChI InChI=1S/C24H28N8O/c1-16-3-5-17(6-4-16)21(7-8-25)29-24(33)20-12-31(13-20)23-22-9-18(14-32(22)28-15-26-23)19-10-27-30(2)11-19/h3-6,9-11,14-15,20-21H,7-8,12-13,25H2,1-2H3,(H,29,33)/t21-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	25
BLUEPRINT MEDICINES CORPORATION US Patent					Assay Description 10,000 HMC1.2 cells were incubated in 22 ul culture media (phenol-red free IMDM, no serum) in each well of a 384-well plate and serum starved overnig...				US Patent US9688680 (2017) BindingDB Entry DOI: 10.7270/Q2NV9GDQ
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit [V560G,D816V] (Homo sapiens (Human))	BDBM175492 (US9688680, 92) Show SMILES COc1ccc(cc1F)-c1cc2c(ncnn2c1)N1CC(C1)C(=O)NCc1ccc(C)cc1 Show InChI InChI=1S/C25H24FN5O2/c1-16-3-5-17(6-4-16)11-27-25(32)20-12-30(13-20)24-22-10-19(14-31(22)29-15-28-24)18-7-8-23(33-2)21(26)9-18/h3-10,14-15,20H,11-13H2,1-2H3,(H,27,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	25
BLUEPRINT MEDICINES CORPORATION US Patent					Assay Description 10,000 HMC1.2 cells were incubated in 22 ul culture media (phenol-red free IMDM, no serum) in each well of a 384-well plate and serum starved overnig...				US Patent US9688680 (2017) BindingDB Entry DOI: 10.7270/Q2NV9GDQ
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit [V560G,D816V] (Homo sapiens (Human))	BDBM175494 (US9688680, 94) Show SMILES Cc1ccc(cc1)[C@H](CCO)NC(=O)C1CN(C1)c1ncnn2cc(cc12)-c1cnn(C)c1 |r| Show InChI InChI=1S/C24H27N7O2/c1-16-3-5-17(6-4-16)21(7-8-32)28-24(33)20-12-30(13-20)23-22-9-18(14-31(22)27-15-25-23)19-10-26-29(2)11-19/h3-6,9-11,14-15,20-21,32H,7-8,12-13H2,1-2H3,(H,28,33)/t21-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	25
BLUEPRINT MEDICINES CORPORATION US Patent					Assay Description 10,000 HMC1.2 cells were incubated in 22 ul culture media (phenol-red free IMDM, no serum) in each well of a 384-well plate and serum starved overnig...				US Patent US9688680 (2017) BindingDB Entry DOI: 10.7270/Q2NV9GDQ
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit [V560G,D816V] (Homo sapiens (Human))	BDBM175495 (US9688680, 95) Show SMILES CC(C)n1cc(cn1)-c1cc2c(ncnn2c1)N1CC(C1)C(=O)N[C@@H](C)c1ccc(F)cc1 |r| Show InChI InChI=1S/C24H26FN7O/c1-15(2)31-13-19(9-27-31)18-8-22-23(26-14-28-32(22)12-18)30-10-20(11-30)24(33)29-16(3)17-4-6-21(25)7-5-17/h4-9,12-16,20H,10-11H2,1-3H3,(H,29,33)/t16-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	25
BLUEPRINT MEDICINES CORPORATION US Patent					Assay Description 10,000 HMC1.2 cells were incubated in 22 ul culture media (phenol-red free IMDM, no serum) in each well of a 384-well plate and serum starved overnig...				US Patent US9688680 (2017) BindingDB Entry DOI: 10.7270/Q2NV9GDQ
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit [V560G,D816V] (Homo sapiens (Human))	BDBM175473 (US9688680, 73 | US9688680, 99) Show SMILES CC[C@H](NC(=O)C1CN(C1)c1ncnn2cc(cc12)-c1cnn(C)c1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C23H24ClN7O/c1-3-20(15-4-6-19(24)7-5-15)28-23(32)18-11-30(12-18)22-21-8-16(13-31(21)27-14-25-22)17-9-26-29(2)10-17/h4-10,13-14,18,20H,3,11-12H2,1-2H3,(H,28,32)/t20-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	25
BLUEPRINT MEDICINES CORPORATION US Patent					Assay Description 10,000 HMC1.2 cells were incubated in 22 ul culture media (phenol-red free IMDM, no serum) in each well of a 384-well plate and serum starved overnig...				US Patent US9688680 (2017) BindingDB Entry DOI: 10.7270/Q2NV9GDQ
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit [V560G,D816V] (Homo sapiens (Human))	BDBM175529 (US9688680, 105) Show SMILES Cc1ccc(CNC(=O)C2CN(C2)c2ncnn3cc(cc23)-c2ccc3C(=O)NCc3c2)cc1 Show InChI InChI=1S/C26H24N6O2/c1-16-2-4-17(5-3-16)10-27-25(33)21-12-31(13-21)24-23-9-20(14-32(23)30-15-29-24)18-6-7-22-19(8-18)11-28-26(22)34/h2-9,14-15,21H,10-13H2,1H3,(H,27,33)(H,28,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	25
BLUEPRINT MEDICINES CORPORATION US Patent					Assay Description 10,000 HMC1.2 cells were incubated in 22 ul culture media (phenol-red free IMDM, no serum) in each well of a 384-well plate and serum starved overnig...				US Patent US9688680 (2017) BindingDB Entry DOI: 10.7270/Q2NV9GDQ
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit [V560G,D816V] (Homo sapiens (Human))	BDBM175530 (US9688680, 106) Show SMILES CC(C)Oc1ccc(cc1)-c1cc2c(ncnn2c1)N1CC(C1)C(=O)Nc1ccc(cc1)C#N Show InChI InChI=1S/C26H24N6O2/c1-17(2)34-23-9-5-19(6-10-23)20-11-24-25(28-16-29-32(24)15-20)31-13-21(14-31)26(33)30-22-7-3-18(12-27)4-8-22/h3-11,15-17,21H,13-14H2,1-2H3,(H,30,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	25
BLUEPRINT MEDICINES CORPORATION US Patent					Assay Description 10,000 HMC1.2 cells were incubated in 22 ul culture media (phenol-red free IMDM, no serum) in each well of a 384-well plate and serum starved overnig...				US Patent US9688680 (2017) BindingDB Entry DOI: 10.7270/Q2NV9GDQ
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit [V560G,D816V] (Homo sapiens (Human))	BDBM175555 (US9688680, 109) Show SMILES Cc1ccc(CNC(=O)C2CN(C2)c2ncnn3cc(cc23)-c2ccc(OC3CC3)cc2)cc1 Show InChI InChI=1S/C27H27N5O2/c1-18-2-4-19(5-3-18)13-28-27(33)22-14-31(15-22)26-25-12-21(16-32(25)30-17-29-26)20-6-8-23(9-7-20)34-24-10-11-24/h2-9,12,16-17,22,24H,10-11,13-15H2,1H3,(H,28,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	25
BLUEPRINT MEDICINES CORPORATION US Patent					Assay Description 10,000 HMC1.2 cells were incubated in 22 ul culture media (phenol-red free IMDM, no serum) in each well of a 384-well plate and serum starved overnig...				US Patent US9688680 (2017) BindingDB Entry DOI: 10.7270/Q2NV9GDQ
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit [V560G,D816V] (Homo sapiens (Human))	BDBM175562 (US9688680, 113) Show SMILES Cc1ccc(CNC(=O)C2CN(C2)c2ncnn3cc(cc23)-c2ccc3OCCOc3c2)cc1 Show InChI InChI=1S/C26H25N5O3/c1-17-2-4-18(5-3-17)12-27-26(32)21-13-30(14-21)25-22-10-20(15-31(22)29-16-28-25)19-6-7-23-24(11-19)34-9-8-33-23/h2-7,10-11,15-16,21H,8-9,12-14H2,1H3,(H,27,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	25
BLUEPRINT MEDICINES CORPORATION US Patent					Assay Description 10,000 HMC1.2 cells were incubated in 22 ul culture media (phenol-red free IMDM, no serum) in each well of a 384-well plate and serum starved overnig...				US Patent US9688680 (2017) BindingDB Entry DOI: 10.7270/Q2NV9GDQ
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit [V560G,D816V] (Homo sapiens (Human))	BDBM175564 (US9688680, 115) Show SMILES CC(C)Oc1ccc(cc1)-c1cc2c(ncnn2c1)N1CC(C1)C(=O)NCc1ccc(C)cc1 Show InChI InChI=1S/C27H29N5O2/c1-18(2)34-24-10-8-21(9-11-24)22-12-25-26(29-17-30-32(25)16-22)31-14-23(15-31)27(33)28-13-20-6-4-19(3)5-7-20/h4-12,16-18,23H,13-15H2,1-3H3,(H,28,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	25
BLUEPRINT MEDICINES CORPORATION US Patent					Assay Description 10,000 HMC1.2 cells were incubated in 22 ul culture media (phenol-red free IMDM, no serum) in each well of a 384-well plate and serum starved overnig...				US Patent US9688680 (2017) BindingDB Entry DOI: 10.7270/Q2NV9GDQ
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit [V560G,D816V] (Homo sapiens (Human))	BDBM175565 (US9688680, 116) Show SMILES Cc1ccc(CNC(=O)C2CN(C2)c2ncnn3cc(cc23)-c2cccc(c2)C(C)(C)O)cc1 Show InChI InChI=1S/C27H29N5O2/c1-18-7-9-19(10-8-18)13-28-26(33)22-14-31(15-22)25-24-12-21(16-32(24)30-17-29-25)20-5-4-6-23(11-20)27(2,3)34/h4-12,16-17,22,34H,13-15H2,1-3H3,(H,28,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	25
BLUEPRINT MEDICINES CORPORATION US Patent					Assay Description 10,000 HMC1.2 cells were incubated in 22 ul culture media (phenol-red free IMDM, no serum) in each well of a 384-well plate and serum starved overnig...				US Patent US9688680 (2017) BindingDB Entry DOI: 10.7270/Q2NV9GDQ
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit [V560G,D816V] (Homo sapiens (Human))	BDBM175567 (US9688680, 118) Show SMILES Cc1ccc(CC(=O)NC2CN(C2)c2ncnn3cc(cc23)-c2ccc(cc2)C(C)(C)O)cc1 Show InChI InChI=1S/C27H29N5O2/c1-18-4-6-19(7-5-18)12-25(33)30-23-15-31(16-23)26-24-13-21(14-32(24)29-17-28-26)20-8-10-22(11-9-20)27(2,3)34/h4-11,13-14,17,23,34H,12,15-16H2,1-3H3,(H,30,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	25
BLUEPRINT MEDICINES CORPORATION US Patent					Assay Description 10,000 HMC1.2 cells were incubated in 22 ul culture media (phenol-red free IMDM, no serum) in each well of a 384-well plate and serum starved overnig...				US Patent US9688680 (2017) BindingDB Entry DOI: 10.7270/Q2NV9GDQ
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit [V560G,D816V] (Homo sapiens (Human))	BDBM175568 (US9688680, 119) Show SMILES CC[C@H](NC(=O)C1CN(C1)c1ncnn2cc(cc12)-c1cnn(C)c1)c1ccc(cc1)C1CC1 |r| Show InChI InChI=1S/C26H29N7O/c1-3-23(19-8-6-18(7-9-19)17-4-5-17)30-26(34)22-13-32(14-22)25-24-10-20(15-33(24)29-16-27-25)21-11-28-31(2)12-21/h6-12,15-17,22-23H,3-5,13-14H2,1-2H3,(H,30,34)/t23-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	25
BLUEPRINT MEDICINES CORPORATION US Patent					Assay Description 10,000 HMC1.2 cells were incubated in 22 ul culture media (phenol-red free IMDM, no serum) in each well of a 384-well plate and serum starved overnig...				US Patent US9688680 (2017) BindingDB Entry DOI: 10.7270/Q2NV9GDQ
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit [V560G,D816V] (Homo sapiens (Human))	BDBM175569 (US9688680, 120) Show SMILES Cn1cc(cn1)-c1cc2c(ncnn2c1)N1CC(C1)C(=O)NCc1ccc(Cl)cc1Cl Show InChI InChI=1S/C21H19Cl2N7O/c1-28-8-15(7-26-28)14-4-19-20(25-12-27-30(19)11-14)29-9-16(10-29)21(31)24-6-13-2-3-17(22)5-18(13)23/h2-5,7-8,11-12,16H,6,9-10H2,1H3,(H,24,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	25
BLUEPRINT MEDICINES CORPORATION US Patent					Assay Description 10,000 HMC1.2 cells were incubated in 22 ul culture media (phenol-red free IMDM, no serum) in each well of a 384-well plate and serum starved overnig...				US Patent US9688680 (2017) BindingDB Entry DOI: 10.7270/Q2NV9GDQ
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit [V560G,D816V] (Homo sapiens (Human))	BDBM175570 (US9688680, 121) Show SMILES Cn1cc(cn1)-c1cc2c(ncnn2c1)N1CC(C1)NC(=O)Cc1ccc(Cl)cc1Cl Show InChI InChI=1S/C21H19Cl2N7O/c1-28-8-15(7-25-28)14-4-19-21(24-12-26-30(19)9-14)29-10-17(11-29)27-20(31)5-13-2-3-16(22)6-18(13)23/h2-4,6-9,12,17H,5,10-11H2,1H3,(H,27,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	25
BLUEPRINT MEDICINES CORPORATION US Patent					Assay Description 10,000 HMC1.2 cells were incubated in 22 ul culture media (phenol-red free IMDM, no serum) in each well of a 384-well plate and serum starved overnig...				US Patent US9688680 (2017) BindingDB Entry DOI: 10.7270/Q2NV9GDQ
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit [V560G,D816V] (Homo sapiens (Human))	BDBM175575 (US9688680, 124) Show SMILES COC(=O)N1CCC(=CC1)c1cc2c(ncnn2c1)N1CC(C1)C(=O)Nc1ccc(cc1)C#N |c:7| Show InChI InChI=1S/C24H23N7O3/c1-34-24(33)29-8-6-17(7-9-29)18-10-21-22(26-15-27-31(21)14-18)30-12-19(13-30)23(32)28-20-4-2-16(11-25)3-5-20/h2-6,10,14-15,19H,7-9,12-13H2,1H3,(H,28,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	25
BLUEPRINT MEDICINES CORPORATION US Patent					Assay Description 10,000 HMC1.2 cells were incubated in 22 ul culture media (phenol-red free IMDM, no serum) in each well of a 384-well plate and serum starved overnig...				US Patent US9688680 (2017) BindingDB Entry DOI: 10.7270/Q2NV9GDQ
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit [V560G,D816V] (Homo sapiens (Human))	BDBM175578 (US9688680, 127) Show SMILES CCC(=O)N1CCC=C(C1)c1cc2c(ncnn2c1)N1CC(C1)C(=O)NCc1ccc(C)cc1 |c:7| Show InChI InChI=1S/C26H30N6O2/c1-3-24(33)30-10-4-5-20(13-30)21-11-23-25(28-17-29-32(23)16-21)31-14-22(15-31)26(34)27-12-19-8-6-18(2)7-9-19/h5-9,11,16-17,22H,3-4,10,12-15H2,1-2H3,(H,27,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	25
BLUEPRINT MEDICINES CORPORATION US Patent					Assay Description 10,000 HMC1.2 cells were incubated in 22 ul culture media (phenol-red free IMDM, no serum) in each well of a 384-well plate and serum starved overnig...				US Patent US9688680 (2017) BindingDB Entry DOI: 10.7270/Q2NV9GDQ
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit [V560G,D816V] (Homo sapiens (Human))	BDBM175579 (US9688680, 128) Show SMILES CN(C)CC1(CN(C1)c1ncnn2cc(cc12)-c1cnn(C)c1)C(=O)NCc1ccc(C)cc1 Show InChI InChI=1S/C25H30N8O/c1-18-5-7-19(8-6-18)10-26-24(34)25(14-30(2)3)15-32(16-25)23-22-9-20(13-33(22)29-17-27-23)21-11-28-31(4)12-21/h5-9,11-13,17H,10,14-16H2,1-4H3,(H,26,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	25
BLUEPRINT MEDICINES CORPORATION US Patent					Assay Description 10,000 HMC1.2 cells were incubated in 22 ul culture media (phenol-red free IMDM, no serum) in each well of a 384-well plate and serum starved overnig...				US Patent US9688680 (2017) BindingDB Entry DOI: 10.7270/Q2NV9GDQ
					More data for this Ligand-Target Pair

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