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Compile Data Set for Download or QSAR

Found 2 hits of ki for monomerid = 315934   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Potassium voltage-gated channel subfamily H member 2


(Homo sapiens (Human))
BDBM315934
PNG
(US10172859, Example 358 | US11065253, Example 358 ...)
Show SMILES OC(c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccn2cccc12
Show InChI InChI=1S/C26H21F2N5O2/c27-20-14-21(28)19(26(34)25-23-2-1-6-33(23)7-5-29-25)13-18(20)24-17-4-3-16(12-22(17)30-15-31-24)32-8-10-35-11-9-32/h1-7,12-15,26,34H,8-11H2
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MMDB

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PC cid
PC sid
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US Patent
1.25E+4n/an/an/an/an/an/an/an/a



Merck Patent GmbH

US Patent


Assay Description
The patch-clamp measurement was carried out at room temperature in whole-cell configuration on human embryonic kidney cells (HEK293) which have been ...


US Patent US9732094 (2017)


BindingDB Entry DOI: 10.7270/Q2J67K1S
More data for this
Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2


(Homo sapiens (Human))
BDBM315934
PNG
(US10172859, Example 358 | US11065253, Example 358 ...)
Show SMILES OC(c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccn2cccc12
Show InChI InChI=1S/C26H21F2N5O2/c27-20-14-21(28)19(26(34)25-23-2-1-6-33(23)7-5-29-25)13-18(20)24-17-4-3-16(12-22(17)30-15-31-24)32-8-10-35-11-9-32/h1-7,12-15,26,34H,8-11H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
1.25E+4n/an/an/an/an/an/an/an/a



Merck Patent GmbH

US Patent


Assay Description
Method for the detection and characterisation of test substances which interfere with the Kv11.1 (hERG) channel: Kv11.1 (hERG, human ether a-go-go re...


US Patent US10172859 (2019)


BindingDB Entry DOI: 10.7270/Q23B626S
More data for this
Ligand-Target Pair