Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50129596 (Bis-(4-fluoro-phenyl)-(3-piperazin-1-yl-propyl)-am...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 60.8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NIDA-IRP Curated by ChEMBL | Assay Description Binding affinity against dopamine transporter was determined by the displacement of [3H]WIN-35428 radioligand in rat brain | J Med Chem 46: 2589-98 (2003) Article DOI: 10.1021/jm030008u BindingDB Entry DOI: 10.7270/Q2H70GJN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50129596 (Bis-(4-fluoro-phenyl)-(3-piperazin-1-yl-propyl)-am...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 133 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NIDA-IRP Curated by ChEMBL | Assay Description Binding affinity against serotonin transporter by displacement of [3H]citalopram in rat brain | J Med Chem 46: 2589-98 (2003) Article DOI: 10.1021/jm030008u BindingDB Entry DOI: 10.7270/Q2H70GJN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus) | BDBM50129596 (Bis-(4-fluoro-phenyl)-(3-piperazin-1-yl-propyl)-am...) | PDB Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 396 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NIDA-IRP Curated by ChEMBL | Assay Description Displacement of [3H]nisoxetine from rat brain norepinephrine transporter | J Med Chem 46: 2589-98 (2003) Article DOI: 10.1021/jm030008u BindingDB Entry DOI: 10.7270/Q2H70GJN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50129596 (Bis-(4-fluoro-phenyl)-(3-piperazin-1-yl-propyl)-am...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.39E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NIDA-IRP Curated by ChEMBL | Assay Description Binding affinity against Sigma receptor type 1 was determined by the displacement of [3H]pentazocine radioligand | J Med Chem 46: 2589-98 (2003) Article DOI: 10.1021/jm030008u BindingDB Entry DOI: 10.7270/Q2H70GJN | |||||||||||
More data for this Ligand-Target Pair |