Found 4 hits of ki for monomerid = 50284296 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50284296
![PNG](/data/jpeg/tenK5028/BindingDB_50284296.png) (CHEMBL4160499)Show SMILES N\C(NNc1nc(Cl)nc(NCc2ccc(cc2)S(N)(=O)=O)n1)=N/S(=O)(=O)c1ccccc1SCc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C25H23ClF3N9O4S3/c26-21-33-23(32-13-15-8-10-18(11-9-15)44(31,39)40)35-24(34-21)37-36-22(30)38-45(41,42)20-7-2-1-6-19(20)43-14-16-4-3-5-17(12-16)25(27,28)29/h1-12H,13-14H2,(H3,30,36,38)(H2,31,39,40)(H2,32,33,34,35,37) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
Similars
| Article PubMed
| 5.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Medical University of Gdansk
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 2 by stopped-flow CO2 hydration assay |
Eur J Med Chem 143: 1931-1941 (2018)
Article DOI: 10.1016/j.ejmech.2017.11.005 BindingDB Entry DOI: 10.7270/Q2HT2RW2 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50284296
![PNG](/data/jpeg/tenK5028/BindingDB_50284296.png) (CHEMBL4160499)Show SMILES N\C(NNc1nc(Cl)nc(NCc2ccc(cc2)S(N)(=O)=O)n1)=N/S(=O)(=O)c1ccccc1SCc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C25H23ClF3N9O4S3/c26-21-33-23(32-13-15-8-10-18(11-9-15)44(31,39)40)35-24(34-21)37-36-22(30)38-45(41,42)20-7-2-1-6-19(20)43-14-16-4-3-5-17(12-16)25(27,28)29/h1-12H,13-14H2,(H3,30,36,38)(H2,31,39,40)(H2,32,33,34,35,37) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
Similars
| Article PubMed
| 44 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Medical University of Gdansk
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 9 by stopped-flow CO2 hydration assay |
Eur J Med Chem 143: 1931-1941 (2018)
Article DOI: 10.1016/j.ejmech.2017.11.005 BindingDB Entry DOI: 10.7270/Q2HT2RW2 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50284296
![PNG](/data/jpeg/tenK5028/BindingDB_50284296.png) (CHEMBL4160499)Show SMILES N\C(NNc1nc(Cl)nc(NCc2ccc(cc2)S(N)(=O)=O)n1)=N/S(=O)(=O)c1ccccc1SCc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C25H23ClF3N9O4S3/c26-21-33-23(32-13-15-8-10-18(11-9-15)44(31,39)40)35-24(34-21)37-36-22(30)38-45(41,42)20-7-2-1-6-19(20)43-14-16-4-3-5-17(12-16)25(27,28)29/h1-12H,13-14H2,(H3,30,36,38)(H2,31,39,40)(H2,32,33,34,35,37) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
Similars
| Article PubMed
| 219 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Medical University of Gdansk
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 1 by stopped-flow CO2 hydration assay |
Eur J Med Chem 143: 1931-1941 (2018)
Article DOI: 10.1016/j.ejmech.2017.11.005 BindingDB Entry DOI: 10.7270/Q2HT2RW2 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50284296
![PNG](/data/jpeg/tenK5028/BindingDB_50284296.png) (CHEMBL4160499)Show SMILES N\C(NNc1nc(Cl)nc(NCc2ccc(cc2)S(N)(=O)=O)n1)=N/S(=O)(=O)c1ccccc1SCc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C25H23ClF3N9O4S3/c26-21-33-23(32-13-15-8-10-18(11-9-15)44(31,39)40)35-24(34-21)37-36-22(30)38-45(41,42)20-7-2-1-6-19(20)43-14-16-4-3-5-17(12-16)25(27,28)29/h1-12H,13-14H2,(H3,30,36,38)(H2,31,39,40)(H2,32,33,34,35,37) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
Similars
| Article PubMed
| 256 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Medical University of Gdansk
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 12 by stopped-flow CO2 hydration assay |
Eur J Med Chem 143: 1931-1941 (2018)
Article DOI: 10.1016/j.ejmech.2017.11.005 BindingDB Entry DOI: 10.7270/Q2HT2RW2 |
More data for this Ligand-Target Pair | |