Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig)) | BDBM50322246![]() (1-((1H-Pyrrolo[2,3-b]pyridine-3-yl)methyl)-4-(4-br...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 15.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Washington University School of Medicine Curated by ChEMBL | Assay Description Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain homogenates after 1 hr by liquid scintillation counting | Bioorg Med Chem 18: 5291-300 (2010) Article DOI: 10.1016/j.bmc.2010.05.052 BindingDB Entry DOI: 10.7270/Q298880H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50322246![]() (1-((1H-Pyrrolo[2,3-b]pyridine-3-yl)methyl)-4-(4-br...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 212 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Washington University School of Medicine Curated by ChEMBL | Assay Description Displacement of [125I]ABN from human dopamine D2 long receptor expressed in HEK293 cells after 60 mins by gamma counting | Bioorg Med Chem 18: 5291-300 (2010) Article DOI: 10.1016/j.bmc.2010.05.052 BindingDB Entry DOI: 10.7270/Q298880H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(4) dopamine receptor (Homo sapiens (Human)) | BDBM50322246![]() (1-((1H-Pyrrolo[2,3-b]pyridine-3-yl)methyl)-4-(4-br...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 620 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Washington University School of Medicine Curated by ChEMBL | Assay Description Displacement of [125I]ABN from human dopamine D4 receptor expressed in HEK293 cells after 60 mins by gamma counting | Bioorg Med Chem 18: 5291-300 (2010) Article DOI: 10.1016/j.bmc.2010.05.052 BindingDB Entry DOI: 10.7270/Q298880H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(3) dopamine receptor (Homo sapiens (Human)) | BDBM50322246![]() (1-((1H-Pyrrolo[2,3-b]pyridine-3-yl)methyl)-4-(4-br...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.98E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Washington University School of Medicine Curated by ChEMBL | Assay Description Displacement of [125I]ABN from human dopamine D3 receptor expressed in HEK293 cells after 60 mins by gamma counting | Bioorg Med Chem 18: 5291-300 (2010) Article DOI: 10.1016/j.bmc.2010.05.052 BindingDB Entry DOI: 10.7270/Q298880H | |||||||||||
More data for this Ligand-Target Pair |