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Compile Data Set for Download or QSAR

Found 4 hits of ki for monomerid = 50385118   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Prostaglandin E2 receptor EP4 subtype


(Mus musculus (Mouse))
BDBM50385118
PNG
(CHEMBL2036308)
Show SMILES O[C@@H](Cc1cccc(c1)-c1ccc2ccccc2c1)\C=C\[C@H]1CCC(=O)N1CCSCCCC(O)=O |r|
Show InChI InChI=1S/C30H33NO4S/c32-28(14-12-27-13-15-29(33)31(27)16-18-36-17-4-9-30(34)35)20-22-5-3-8-24(19-22)26-11-10-23-6-1-2-7-25(23)21-26/h1-3,5-8,10-12,14,19,21,27-28,32H,4,9,13,15-18,20H2,(H,34,35)/b14-12+/t27-,28+/m0/s1
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PubMed
0.600n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by scintillation counting


Bioorg Med Chem 20: 3502-22 (2012)


Article DOI: 10.1016/j.bmc.2012.04.008
BindingDB Entry DOI: 10.7270/Q2D50P0B
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Mus musculus (Mouse))
BDBM50385118
PNG
(CHEMBL2036308)
Show SMILES O[C@@H](Cc1cccc(c1)-c1ccc2ccccc2c1)\C=C\[C@H]1CCC(=O)N1CCSCCCC(O)=O |r|
Show InChI InChI=1S/C30H33NO4S/c32-28(14-12-27-13-15-29(33)31(27)16-18-36-17-4-9-30(34)35)20-22-5-3-8-24(19-22)26-11-10-23-6-1-2-7-25(23)21-26/h1-3,5-8,10-12,14,19,21,27-28,32H,4,9,13,15-18,20H2,(H,34,35)/b14-12+/t27-,28+/m0/s1
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PubMed
2.10E+3n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by scintillation counting


Bioorg Med Chem 20: 3502-22 (2012)


Article DOI: 10.1016/j.bmc.2012.04.008
BindingDB Entry DOI: 10.7270/Q2D50P0B
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype


(Mus musculus (Mouse))
BDBM50385118
PNG
(CHEMBL2036308)
Show SMILES O[C@@H](Cc1cccc(c1)-c1ccc2ccccc2c1)\C=C\[C@H]1CCC(=O)N1CCSCCCC(O)=O |r|
Show InChI InChI=1S/C30H33NO4S/c32-28(14-12-27-13-15-29(33)31(27)16-18-36-17-4-9-30(34)35)20-22-5-3-8-24(19-22)26-11-10-23-6-1-2-7-25(23)21-26/h1-3,5-8,10-12,14,19,21,27-28,32H,4,9,13,15-18,20H2,(H,34,35)/b14-12+/t27-,28+/m0/s1
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>1.00E+4n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from mouse EP1 receptor expressed in CHO cells after 20 mins by scintillation counting


Bioorg Med Chem 20: 3502-22 (2012)


Article DOI: 10.1016/j.bmc.2012.04.008
BindingDB Entry DOI: 10.7270/Q2D50P0B
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype


(Mus musculus (Mouse))
BDBM50385118
PNG
(CHEMBL2036308)
Show SMILES O[C@@H](Cc1cccc(c1)-c1ccc2ccccc2c1)\C=C\[C@H]1CCC(=O)N1CCSCCCC(O)=O |r|
Show InChI InChI=1S/C30H33NO4S/c32-28(14-12-27-13-15-29(33)31(27)16-18-36-17-4-9-30(34)35)20-22-5-3-8-24(19-22)26-11-10-23-6-1-2-7-25(23)21-26/h1-3,5-8,10-12,14,19,21,27-28,32H,4,9,13,15-18,20H2,(H,34,35)/b14-12+/t27-,28+/m0/s1
PDB

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PC cid
PC sid
UniChem

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Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counting


Bioorg Med Chem 20: 3502-22 (2012)


Article DOI: 10.1016/j.bmc.2012.04.008
BindingDB Entry DOI: 10.7270/Q2D50P0B
More data for this
Ligand-Target Pair